I'm gonna be honest I started my epi at weak two then deca drol a little while after. So the transderm did not get a full two weeks to soak before I started. Coulnt wait. Didn't help me any. After about a week of epi the lethargy set in and I wasn't able to lift as heavy either physically or mentally. So I can attest to the lethargy caused by the epi and also the ability for the transderm to make it go away. I would recommend any one to wait the two weeks. There was a couple of days where I didn't care I the world stopped turning. As for results, up until now only a little definition. Now getting some pumps and siZe coming on. I'm only weighing before and after. It is more about how I feel and look.