Did someone say Karma???
about the slin....
Bro...please for your own good. Do some research on slin. This stuff can have you DEAD within 15 minutes of your shot. Its really serious shit.
anyway....having said that.....
You should start out taking 2iu after your workout.
Everyday that you workout, you should take slin. DO NOT take on days where you dont workout.
Each day...up your dosage 1 iu....until you get to 10iu
Every 1 iu you inject.....should be immediatly followed by 10 grams of high glycogen carbs.....(CARBO-FORCE drink)
Here is some info that i've collected from this message board. Also, if you do a search for threads stared by me, you'll find alot of posts on GH & Slin. Hope this helps!
Humulog
Insulin safety
Do not use slin alone. Have someone there 2.5 / 4 hrs after.
Symptoms of hypoglycemia include disorientation, headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea.
pancake syrup, coke, sugary stuff. I bought glucose tablets at walmart
Take the carbs and protein together immediately after injecting the slin. Take the protein with the carbs because the protein is pushed into the muscles with the slin also (creatine too).
Before an hour passes you should eat a normal balanced meal (high protein low fat with carbs).
Consume another small high protein medium carb low fat meal at 2.5 hours after the injection. Congrats you lived.(keep some gatoraid on hand just to make sure because your not gonna have a lifeline)
Where do I keep it? (STORAGE)
Cold place and to avoid freezing. The refrigerator is a good spot. Unrefrigerated insulin can be kept of 28 days as long as it stays in a cool and dark place.
Where/how do I inject insulin?
The best sites for insulin injection are in the subcutaneous tissue of the abdomen(avoid the area close to bellybutton) .Usually, you should not inject within 1 inch of the same site within 1 month.
How much insulin should I take?
I recommend never using over 10IU.
In general Dosages used are usually 1 IU per 20 pounds of lean bodyweight.
So a 220lb bodybuilder with 9% body-fat would use 10iu of insulin(aprox200lb lean mass/20 = 10iu
First-time users should start at a low dosage and gradually work up.
For example, first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout until you reach your calculated dose or determine a maximum personal dose(some people are more sensitive to insulin sides like hypoglycemia).
When do I take insulin?
It is my opinion that you should only take insulin after a work out, never before or when not working
When do i eat after using insulin?
Immediately!!! You should immediately take a carbohydrate AND protein drink after taking you're insulin.
Eat a meal at about an hour after using insulin.
Consume another small high protein medium carb low fat meal at 2.5 hours after the injection.
keep some gatoraid on hand just to make sure.
What do I eat after using insulin?
zero fat intake for 4 hours after taking insulin.
Before an hour passes you should eat a normal balanced meal(high protein low fat with carbs).
At 2.5 hours after the injection you should Consume a small meal.
keep some gatoraid on hand just to make sure.
***Some insulin users recommend far less carbs than I have stated above. This is a personal decision you will have to make since it could be very dangerous...Even deadly! My opinion is to take the carbs and learn to diet after bulking if you gain too much fat.***
How long should/can I take insulin?
Short cycles please because you could have side effects. It is suspected that you could become an insulin dependant diabetic but I have never seen proof, but is it worth the risk? I would only use it a few times a week(maximum 4 on 3 off) for no more than 3/4 weeks.
What should I avoid while using insulin?
Do not change your workout in the middle of a cycle of insulin. Changes in how much you exercise can change the amount of insulin you can tolerate and maintain blood sugar levels.
Do not change the brand of insulin or syringe that you are using without first talking to a doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not.
Do not use insulin if you are sick with a cold, flu, or fever. These illnesses may change your insulin requirements..
Do not use any insulin that is discolored, looks thick, has particles in it, or looks different from the way it looked when you bought it.
Do not use OTC drugs that will cause drowsiness within 6 hours of using insulin.
Do not go to sleep within 4/6 hours of using insulin since you can develop hypoglycemia while asleep and not have warning signs.
What are the possible side effects of insulin besides hypoglycemia?
Rarely, people have allergic reactions to insulin. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
THE SKINNY ON INSULIN
There has been increasing popularity, and curiosity, concerning exogenous use of "the most anabolic hormone in the body". This makes it necessary to inform people how to maximise muscle mass acquisition and minimise horrid body fat accumulation when using it. The following is a detailed description of the effects of exogenous insulin use, combined with several other common bodybuilding drugs, from a muscle anabolism and fat catabolism point of view.
*WARNING*
Morons and bodybuilding novices should not consider insulin use, because it has one of the highest potentials for danger of all bodybuilding drugs. Its' use requires complete discipline and control over ones' environment. Insulin misuse should not be taken lightly because death's from it occur almost weekly. If that doesn't scare you, consider this: it can make you very, VERY, fat.
Before we delve in to the insulin alchemy, we should understand why insulin does such a good job of muscle and fat accumulation. Of course insulin is known as "the storage hormone", which means that it stores various macronutrients in different body tissues. Protein storage comes directly from amino acid uptake and protein synthesis in skeletal muscle. This is what we want. Fat storage comes from: directly reducing fat release from fat cells (adipocytes), increasing the rate at which the other macronutrients are converted in to fat, and inducing fat storage. This is what we don't want. Carbohydrate storage also occurs, but only significantly in special circumstances (discussed later). Now the fun part.
INSULIN AND ANABOLIC STEROIDS
Of course when everyone thinks of bodybuilding drugs anabolic steroids (AS) are the first things to come to mind, but how do they work with insulin? VERY WELL! AS decrease insulin induced fat accumulation through a number of ways. One is through creatine synthetase, which is an enzyme that goes crazy after workouts trying to store carbohydrates in the muscles (as glycogen, creatine phosphate etc.). For every gram of carbohydrate stored in muscle, roughly four grams of water go along with it (this is how creatine monohydrate achieves such dramatic results). How does this relate to insulin and AS? Well, the "harder" AS (exemplified by oxymethelone) increase creatine synthetase levels dramatically, giving insulin a place to do its' job and store carbohydrates. Okay, this also counts for a combined anabolic effect, but it prevents insulin from converting any "excess" carbohydrate in to fat (which would subsequently be stored)! AS also decrease levels of the main fat storage enzyme that insulin increases (called lipoprotein lipase). A big effect is through glucocorticoid antagonism, which means that AS indirectly increase insulin sensitivity (as well as act anti-catabolically). This allows insulin to bind to its' receptors more easily and accomplish its' job rather, than converting more macronutrients in to fat. Finally, the demand for nutrients by muscles is so high, in an AS enhanced state, that there is rarely any excess of nutrients to actually be stored as fat! A mere 400 mgs of enanthate didn't allow me to accumulate fat whether I was using insulin or not.
From a muscular anabolic perspective, there is a synergistic effect between AS and insulin. This is because they both directly stimulate protein synthesis as well as other mechanisms. One such mechanism involves AS hepatic mediated somatomedin release. Simply put: IGF-1 production in the liver. Again, the more powerful the AS, the more IGF-1 release, with orals having a much greater effect than injectables. Insulin increases the duration of time that IGF-1 is active in the bloodstream, and enhances receptor mediated IGF-1 activity (all through enhancing specific IGF-1 binding proteins). Another great combined effect is that insulin reduces the amount of Sex Hormone Binding Proteins (SHBP) in the blood stream. This allows more AS to be active and do their job of making you grow! Great effects were seen while using 10 units of insulin only three times a week, with AS. For the first few weeks of my next cycle I'm not going off the stuff, and I expect the effects to be scary!
INSULIN AND THE C/A/E STACK
In case you've been living on Mars for the past few years, CAE stands for Caffeine, Aspirin, and Ephedrine. This stack has been shown to synergistically strip off fat, while preserving muscle mass. It is considered here because it is the minimum requirement, while using insulin, to prevent you from looking like the StayPuft marshmallow man. Also of benefit is that it is cheap and easily accessible. Using three times a day helps slow the fat accumulation, but strict dietary control is also necessary. The ephedrine: suppresses appetite, stimulates thermogenesis, and promotes and fat release from cells (beta receptor, and catecholamine, mediated), while the other two components of the stack increase thermogenesis by inhibiting certain enzymes and transmitters that try to slow down the thermic effect. Ultimately the appetite suppression effectiveness of ephedrine wears off, but this is replaced by a greater thermogenic effect (5-deiodinase, or Beta-3, mediated). The CAE stack does nothing for muscle anabolism in a hyper caloric situation, but that's what the insulin is for.
INSULIN AND CLENBUTEROL
This "soon to be classic" post-cycle stack not only increases muscle mass, but keeps fat off at the same time. Fat loss from clen is legendary for the first two weeks. After that time, the beta-2 receptors that it activates, attenuate (because of the extremely high binding specificity), dropping the fat burning effects to minimal levels. There should still be beta-1 receptor activation (which stimulates fat release from adipocytes) and beta-3 stimulation (the big thermogenic wonders), because they attenuate slower or not at all (respectively) compared to beta-2 receptors. Clen is a much better fat burner than ephedrine, due not only to its' higher receptor specificity, but also due to it's extremely long half life (the exact reason it's not approved for use in humans). This means that the drug is constantly burning fat, especially at night when serum glucose, and insulin, are low. Using aspirin and caffeine might slow the receptor attenuation, or at least increase the thermogenesis while its there (I can certainly attest to this!). Why hasn't anyone done this sooner? Clen, like AS, directly combats the fat storing enzyme that insulin promotes (lipoprotein lipase again) in white fat. However it actually increases this enzymatic activity in brown fat (hence the thermogenesis) and muscle. The latter event could promote muscle anabolism through a similar mechanism to HMB, or at least increases muscular fat storage (merely increasing muscle size). This may not seem significant, but the way that people are going nuts over synthol, you never know! The mechanism of action of clens' muscle building effect is not known, but it appears to be anti-catabolic rather than directly anabolic. It should be noted that this anticatabolism is not beta receptor mediated , and therefore does not attenuate. At any rate, the combined effect of the two drugs can be noticeable muscle gain while keeping fat off for the first two weeks. Can fat accumulation be slowed with this stack continue past this time? I'll let you know!
THE SKINNY ON INSULIN: PART II
There has been increasing popularity, and curiosity, concerning exogenous use of "the most anabolic hormone in the body". This makes it necessary to inform people how to maximize muscle mass acquisition and minimize nasty body fat accumulation when using it. The following is the second article dealing with the effects of exogenous insulin use, combined with several other bodybuilding drugs and supplements, from a muscle anabolism and fat catabolism point of view. Part I outlined insulin use combined with: anabolic steroids, the C/A/E stack, and clenbuterol.
*WARNING*
Insulin has one of the highest potentials for danger of all bodybuilding drugs. It shouldn't be screwed around with.
INSULIN AND GROWTH HORMONE
Growth hormone (GH) is one of the most sought after bodybuilding drugs due to its' legendary abilities to strip off body fat and increase muscle mass. The former is accomplished through direct lipolysis (fat release from adipocytes), which GH does to an incredible degree. Muscle mass acquisition is accomplished through: the direct stimulation of protein synthesis, increasing amino acid uptake by muscle cells, and by greatly stimulating IGF-1 synthesis in the liver. It is this last point that is of interest to us because it is the main anabolic mechanism for GH, and it is also where insulin comes in to play. More than half of GHs' anabolic effect is due to IGF-1 production, but unfortunately this is quite often wasted. This is because IGF-1 has an extremely short half life in the bloodstream, so it usually doesn't reach many target tissues (muscles for our interest) to exert maximum anabolic effect. To rectify this situation, insulin can be used to increase the amount of an IGF-1 binding protein (specifically IGF1-BP3) that actually helps IGF-1 to reach the muscles and exert its' extreme anabolism. Insulin also reduces the amount of "bad" IGF1 BP's, (BP's 2 and 4) that would normally interfere with IGF-1 uptake and use by muscle. To say that there is a synergistic effect between insulin and GH doesn't do the combination justice. It makes me shudder to think of the hundreds of thousands of dollars spent on GH, without using it to the maximum anabolic potential. From a fat loss perspective, GH is incredible. It should directly negate the lipogenic effect of insulin, leaving you with one KICK ASS combination.
INSULIN AND THYROID HORMONES
With the huge increases in fat mass often accompanying insulin use, it seems like a simple solution to use thyroid hormone. Unfortunately, this doesn't work out very well. The reason is that thyroid hormone (specifically T3 and possibly T4) increases the amount of the "bad" IGF1-BP's mentioned earlier;IGFBP2 and IGFBP4. This may not seem like a big deal if one is not using drugs to stimulate IGF-1 synthesis, but IGF-1 levels are naturally stimulated through acts like stretching, and even natural testosterone/GH increases. All of these things normally accompany workouts (if you know what you're doing), which is the best time to take insulin. So by having all of the free IGF-1 bound by IGFBP3s' evil siblings, much of the anabolic effect of insulin is lost! Since T3 (triiodothyronine) is the main culprit, does that mean that T4 (tetraiodothyronine) can be used with no detrimental effect? NO, because T4 is mostly effective by converting to T3, which leaves you with the same problem. In fact, T4 could very well do the same thing. So if you want to maximize the anabolic effectiveness of insulin while minimizing bodyfat accumulation, use another fat burner and leave the thyroid alone.
INSULIN AND CREATINE
These compounds may have an anti-synergistic effect on each other, meaning that the combined effect is less than the sum of the individual effects. This possibility exists due to both components' ability to store water in muscle cells. If only a certain amount of water can be stored in the cells through each mechanism of action, then the anti-synergistic condition would exist. Although this condition is unlikely, it is worth mentioning for future experimentation purposes (lab rats know where to contact me). One definite advantage of this combination is that creatine is best absorbed by the muscles when insulin serum levels are high, insuring maximum effectiveness. BTW-if one is not doing something as fundamental as using creatine, there is no way they should be using insulin (so basically insulin use requires creatine use).
INSULIN AND HCA
Getting straight to the point, unless you are a moron and are eating fat during insulin use, or you have crappy insulin sensitivity, HCA is the second most effective fat gain inhibitor next to clenbuterol (which is only more effective due to its' ridiculously long half life). Hydroxy Citric Acid (HCA) is the main ingredient in Citrimax, and is a bargain in terms of its': relative effectiveness (when using insulin), cost (cheap, cheap, cheap), and availability. It works by inhibiting an enzyme called ATP citrate ly(s)ase (ACL), which basically converts ingested carbs to fat (which insulin promptly stores). This is normally NOT a big deal since ACL levels are normally low in most humans. However, insulin drastically increases ACL levels (which should make sense based on what you now know about insulin) accounting for most of the, responsible use, fat gain associated with insulin use. This is the most exciting find since the discovery of insulin as an anabolic! Using insulin and not gaining fat while gaining muscle? What a concept! Although I don't like to go into the details of use directly, I believe it is warranted here. 500-750mgs HCA should be taken with or within half an hour after the insulin shot. The usually recommended 250mgs is ineffective in dealing with the drastic increase in ACL levels. The HCA is taken with the shot because both start to work on about one half hour, so the HCA can begin to be effective at the same time that insulin is trying to increase ACL levels. This regimen (only 3X500mgs HCA) prevented fat gain during a day when I used 3 separate insulin shots! To make things even better there is a mild glycogen storage property associated with HCA use. Since ingested carbs cannot be converted to, or stored as, fat, they are generally stored (due to insulin) as glycogen in muscle giving the user a mild but noticeable pump (similar to the first day of creatine use). To end this portion of the list, I give HCA my highest recommendation as the number 1 supplement to use with insulin!
INSULIN AND FLAX SEED OIL
Short and sweet. Don't use flax seed oil with insulin, because it is fat and *will* be stored. The fat storage rules totally change when insulin is involved (I even avoid vitamin E capsules because mine are oil based).
INSULIN AND CLENBUTEROL UPDATE
This may look like an ideal combination at first, but research has shown why my muscle gains with this combo were minimal. Clen reduces insulin sensitivity, which means that insulin will have a much harder time doing its' anabolic job on muscle tissue. In addition to storing amino acids as muscle, insulin also stores carbs in muscle (which gives a very "full" look to the muscles), which reduced insulin sensitivity also hinders. This is also combined with the fact that clen reduces Glut-4 transporters (which allow glucose passage, and subsequent storage, into muscle) in skeletal muscle which probably accounts for clens' ability to reduce muscle glycogen concentration. On a lighter note, the fat burning effects of clen are potentiated by aspirin and caffeine (through personal experience) but still die off after a few weeks. Overall the only time I would recommend this combination occurs when coming off a cycle and every bit of anabolism is needed, otherwise the two drugs have a bad effect (from an anabolic standpoint) on each other.
SIMPLE TIPS TO MAXIMIZE ANABOLISM AND MINIMIZE FAT GAIN WITH INSULIN USE
-USE HCA
- use testosterone enhancing compounds to increase hepatic IGF-1 production
- only use insulin first thing in the morning or during/after workouts
- don't consume *any* fat 2 hours before (due to digestion time) or one hour after (due to induced enzyme activity) insulin use
- stretch to locally increase IGF-1 levels
- continually eat protein spread over the 4-5 hour duration of insulin activity
Finally, my favourite tip from Docroid: (I) use one shot of insulin just before a one hour workout and another shot two hours after the first. This creates synergism between the activity of the two shots by the later shot increasing in activity at the same time as the first shot decreases in activity, giving one a steady high insulin level at the most important time for anabolism! The only time I can say that I have seen dramatic results from insulin use (in terms of muscle anabolism) occurs when I do this "technique". HOWEVER, this is *very* tricky, in terms of serum glucose levels, even for seasoned insulin users. After using for a while, one can get used to the "feel" of insulin, blood sugar crashes, feeding times etc. but things change when one has a high level of insulin for 3-4 hours straight. I've had to eat every hour for three hours during one of my first attempts at this technique, but every two hours some other attempts. This is the only time I don't feel secure with my own insulin use. It's actually a good thing I can now recognize what a blood sugar crash feels like or I'd probably be dead due to this technique. I don't recommend this technique to anyone (and if that's not a big deal to you, just remember who is writing this) but if you feel like using it, make sure that you have had a couple of, (horrible) insulin induced, serum glucose crashes so you can recognize the early warning signs for when you have them (and you *will* have them).
THE SKINNY ON INSULIN: PART III
*WARNING*: Insulin is not a drug to be taken lightly. It's use can harm or even kill an ignorant user. If you plan on using, educate yourself and at least read the last part of this article.
INSULIN AND ANDROSTENDIONE
This combo has potential due to the interesting ability of insulin to increase levels of 17B hydroxysteroid dehydrogenase(17B), which is the enzyme that converts andro. into testosterone. If the increase is anything near the 17B levels that women have, this could become the stack for "natural" Ïbodybuilders. Another possible benefit of this stack is the idea that insulin probably exhibits mild anti-aromatase properties. If this occurs to any significant level it could be great in increasing the 17B levels even more! Although I hate to rain on this theory parade, I have to say that I can't notice ANY anti-aromatase activity from insulin(see first update section). Other possible benefits of this stack are shown in the first part of this series under:
"INSULIN AND ANABOLIC STEROIDS". Of course any potential similarities with AS would be drastically minimized with andro. It should be noted that the term "natural" is used quite loosely.
INSULIN AND CAPTOPRIL
Captopril is an angiotensin converting enzyme(ACE)inhibitor. Its' medical function is to reduce blood pressure. The reason it is included here is because it can have great effects with insulin and AS. I wouldn't reccomend captopril to anyone unless you are hypertensive or are using AS, because it can drop blood pressure to a sub-normal level. A reason captopril is so great is because it increases endogenous growth hormone levels, which you know can be amazing, assuming you've read last month's article. Another benefit to captopril is its' decrease in protein urea(protein loss in urine). No other drug I'm aware of, including AS, GH, or insulin, does this. This means that there will be more protein for those other anabolic drugs to assimilate! Another great use of captopril is the fat loss effect it has. For me it removes the necessity of HCA while using insulin (with AS). Although I still use one 250mgs of HCA/day just for good measure, I could probably get away witho!ut it despite the extreme carb intake after a workout. On a more esoteric note, long term captopril use actually prevents the formation of new Alpha2 adregenic receptors, which would further potentiate fat loss. Also, water retention is minimized through captopril use, which ties into the blood pressure effects. A potential risk while using captopril with insulin is that both drugs do a good job of making one tired/sleepy. Add in a late night, high intensity workout and you'rer ready for bedtime.
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