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How to Measure Liquidex

Well I had bought some of this to try out but to be honest I hadn't even opened mine because I had no idea how I was going to measure it out... thanks bro...
 
OK, for the tech-heads out there, here goes, off the top of my head .......

There are a few variables as people have mentioned.

Given a certain liquid, and a certain surrounding pressure (air pressure) and a certain physical configuration (like the end of the needle) then you have still several variables which come into play:


Temperature

This is important because variations in temperature will change viscosity, which will effect the droplet size. However, at normal room temp (68-74F) this should remain fairly stable with that range.


Pressure

This could be an issue. At one extreme, if you jammed the plunger down - this would obviously effect drop size! It would probably be a stream!

OK, maybe not, thats some fairly thick stuff.

The key is that you want to apply enough pressure so that the "drop" forms by having the liquid pool up on the tip, and to continue to do so .... to form into a drop ..... and because of surface tension of the liquid against the needle, the drop will get larger, but still hold on .... then at some point, the gravitational pull on the liquid is such that it overcomes the surface tension which tends to make the liquid "cling" to the end of the needle.

When gravity pulls down more than the surface tension can hold, a drop ..... drops.

So its imprtant to push the plunger slowly enough so that the drop formaulation is almost entirely consisting of this effect of gravity-vs-surface-tension, and NOT due to the mechanical effect of liquid "pushing" itself off the needle tip.

And you though the OTHER post was technical. LOL

In any event, push slowly and consistently. I was dropping at about 1 per second. That seemed fine.
 
good post, now all i need is to find an 18 gauge needle, anyone know where i can get one w/out having to purchase 100 of them? thanks
 
well, many guys use 18g pins for withdrawing. I am sure that if you know anyone at all locally who is into this ...... they should have a spare or two around.
 
why dont you just buy a empty vial draw the 20cc or liquidex out and add 20 more cc of glyerol one guy has them both that would bring down the mg to 2mg per cc to me that sounds easier than doing a bunch of drops
 
Riker29 said:
I just did a small experiment that may help some other guys.

Liquidex, the liquid sort of "generic" version of Arimidex, is a very concentrated substance, with 4 mg/ml being its rated concentration.

Arimidex is very potent (and not cheap either) and in many cases a person only needs to do like 1/4 mg of it for it to be effective.

But at that concentration,

1/4 mg of Arimidex.

in Liquidex at 4 mg/ml, means that ,

you would need to adminster 1/16 of a ml (cc)!

How the hell do you measure that?

Well, here is what I did.

The formulation of a "drop" of a liquid is actually a fairly controlled and repeatable process. Meaning, if all factors (liquid viscosity, temperature, etc.) are the same, the amount of liquid in each drop is fairly constant (if the drop is formed around a constant source .... lilke .... the heads of a hollow needle .....).

So, I took a syringe, and sucked up like 3 CCs+ into it.

Wiwth an 18 gauge needle on the syringe, I carefully, slowly, pushed down the plnger, ....... and counted each drop ....

And after several trials, with very low amount of "drift" or changes in data, it turns out that ...


Liquidex, through an 18 gauge needle, at room temp, with the needle held stright down, will create 50 drops per ml.


So, extraploating from that (with a slight amount of "rounding" error),

When using Liquidex, take an 18 gauge needle and with the liquid at room temp, and with the needle held straight down,

for 1 mg Arimidex, measure 12 drops.

for 1/2 mg of Arimidex, measure 6 drops.

for 1/4 mg of Arimidex, measure 3 drops.


Hope this helps some people out there.

And for those that were thinking "did this guy WASTE all of that Liquidex?" - not a chance. I "dropped" it into the back end of another syringe, and then placed it back into the vial.
How about a tuberculin syringe?. Its 1 cc and in 1/10cc increments. You can add whatever gauge needle that you like
 
apbt549 said:
why dont you just buy a empty vial draw the 20cc or liquidex out and add 20 more cc of glyerol one guy has them both that would bring down the mg to 2mg per cc to me that sounds easier than doing a bunch of drops

Well, how would you mix it? The liquid is quite thick, simply having them in the same syringe wont really get it mixed properly, you would have to stir it somehow - think about it - how do you stir the contents of a loaded syringe? Not impossible, but a pain none the less.
 
Re: Re: How to Measure Liquidex

Shrebly said:
How about a tuberculin syringe?. Its 1 cc and in 1/10cc increments. You can add whatever gauge needle that you like

That would work GREAT. However I for one have never seen one of these, and I dont think its the type of syringe which is sittest around in the typical AS usres bag of goodies.

Fromn what I have been told (not personal experience) most of the small-capacity syringes do not have removeable needles. So, finding a small-capacity syringe (like 1 cc) which also has a needle large enough (like 18g) for Liquidex may be difficult.

If you DIDS have a 1 cc syringe that you could pop an 18 Gauge removeable needle onto, that would work great.

But, I for one dont have one. So I am drop-counting.
 
I like the methods here for measuring, but IMHO if your not using Anastrazole at 1mg/day you are missing out on what its all about. Diluting I think is one of the best methods but the droppers are consistent.
 
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