How do you break down to 250iu of HCG during a cycle?

[mma man]

I’d like to take HCG during my cycle this time in an attempt to avoid the very obvious nut shrinkage that I have had to deal with in the past. As a single guy that likes to get around as much as I can, it’s embarrassing and difficult to explain. When doing research I’ve found that 250 iu of HCG every 4 days while on a cycle seems to be a fairly consistent practice, but here is my challenge. All I have is vials that contain 5000 iu each and when mixed with all the water that came with it, that only amounts to approximately 1ml. How in the world do you gauge and successfully inject 1 twentieth of a ml much less accurately do that every 4 days throughout the cycle?

I’m doing a rather low dose of sust 250 every 4 days along with 400cc’s of EQ every 5 days and am still having nut shrinkage issues. Am I being stupid or missing something, and does anyone have any other realistic advice to stop or minimize the nut shrinkage?

 

[dmc777]

I’d like to take HCG during my cycle this time in an attempt to avoid the very obvious nut shrinkage that I have had to deal with in the past. As a single guy that likes to get around as much as I can, it’s embarrassing and difficult to explain. When doing research I’ve found that 250 iu of HCG every 4 days while on a cycle seems to be a fairly consistent practice, but here is my challenge. All I have is vials that contain 5000 iu each and when mixed with all the water that came with it, that only amounts to approximately 1ml. How in the world do you gauge and successfully inject 1 twentieth of a ml much less accurately do that every 4 days throughout the cycle?

I’m doing a rather low dose of sust 250 every 4 days along with 400cc’s of EQ every 5 days and am still having nut shrinkage issues. Am I being stupid or missing something, and does anyone have any other realistic advice to stop or minimize the nut shrinkage?

First get you some bacteriostatic water. Mix 1mL in with your 5000iu vial and inject it in to an empty sealed sterile vial. Next draw 4mL of you B water out and inject into the vial. Swirl it around. The 25 mark should be 250ius and the 50 or half a mL should be 500ius. Basically you want a quarter of a Ml.

 

[Thermidor]

Hi. I bought my kit for making up HCG from here I made the 5000iu with 10cc of bac water, and injected it back into the sterile continer, which I store in the fridge in a plastic food tub. I inject .25cc every other day sub-cutaneously in the belly. This gives 125iu every other day - which apparently more accurately mimics the bodys own level. HCG has a half life of 33 hours (see the quote below from the manufacturer).

I'm no expert - but I did a lot of research before choosing this dosage.

Pharmacokinetics
Maximal plasma hCG levels will be reached in males approximately 6 and 16 hours after a single intramuscular or subcutaneous injection of hCG, respectively and in females after approximately 20 hours. HCG is approximately 80 per cent metabolized, predominantly in the kidneys. Intramuscular and subcutaneous administration of hCG were found to be bioequivalent regarding the extent of absorption and the apparent elimination half-lives of approximately 33 hours. On basis of the recommended dose regimens and elimination half-life, cumulation is not expected to occur.



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[gunnz]

If you mixed 5000iu with 10ml bact. water , you will need to inject 1/2 a ml.

 

[miplank]

Take your HCG, Get a vial of bac water.


Crack the amp, and inject 1cc of bac water. Now draw 3 ml of bac water out and transfer it to a sterile vial. Now transfer the 1cc of HCG from the amp to the sterile vial.


Now you have 4cc's of reconsituted HCG.

5000IUs/4ML bac water=1250iu's per ml

1250/10=125ius per 10 on the slin pin.

Draw to the 20 on a slin pin and you have your 250ius.

Store remaining solution in the fridge.

 

[Big_Joe]

I’d like to take HCG during my cycle this time in an attempt to avoid the very obvious nut shrinkage that I have had to deal with in the past. As a single guy that likes to get around as much as I can, it’s embarrassing and difficult to explain. When doing research I’ve found that 250 iu of HCG every 4 days while on a cycle seems to be a fairly consistent practice, but here is my challenge. All I have is vials that contain 5000 iu each and when mixed with all the water that came with it, that only amounts to approximately 1ml. How in the world do you gauge and successfully inject 1 twentieth of a ml much less accurately do that every 4 days throughout the cycle?

I’m doing a rather low dose of sust 250 every 4 days along with 400cc’s of EQ every 5 days and am still having nut shrinkage issues. Am I being stupid or missing something, and does anyone have any other realistic advice to stop or minimize the nut shrinkage?

There is a reason that hCG comes in vials of 5000 iu. That's the correct dosage!!! All the BS on line about doing 250 to 500 iu is crap. It was started by a guy that has a clinic called "All Things Male" He clams to be a leader in the field but has no articles published at all. He made some posts on-line with this bull shit way to use hCG and all it does is keep people coming back to his clinic.

If you put a little time into reading articles on pub med you will find out that nobody in the medical community follows this guys ideas.

Here is an article from pubmed where they studied normal men that had been shutdown from testosterone injection:

Follicle-stimulating hormone and human spermatogenesis.
Bremner WJ, Matsumoto AM, Sussman AM, Paulsen CA.

The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m. weekly to suppress luteinizing hormone (LH) and FSH, until three successive sperm counts revealed azoospermia or severe oligospermia (sperm counts <3 million/ml). Then, while continuing T, human chorionic gonadotropin (hCG) 5,000 IU i. m. three times weekly was administered simultaneously to replace LH activity, leaving FSH activity suppressed. The effect of the selective FSH deficiency produced by hCG plus T administration on sperm production was determined.Sperm counts (performed twice monthly throughout the study) were markedly suppressed during T administration alone (1.0+/-1.0 million/ml mean+/-SE, compared with 106+/-28 million/ml during the control period, P < 0.001). With the addition of hCG to T, sperm counts returned toward normal (46+/-16 million/ml, P < 0.001 compared with T alone). In two subjects, sperm counts during hCG plus T returned into the individual's control range. Sperm motility and morphology were consistently normal in all men during hCG plus T.Serum FSH levels by RIA were normal (110+/-10 ng/ml) in the control period and were suppressed to undetectable levels (<25 ng/ml) in the T alone and hCG plus T periods. Urinary FSH excretion was markedly suppressed in the T alone (60+/-15 mIU/h-2nd IRP, P < 0.01) and hCG plus T (37+/-9 mIU/h, P < 0.01) periods compared with the control period (334+/-78 mIU/h).We conclude that spermatogenesis as assessed by sperm counts, motilities, and morphologies may be reinitiated and maintained at normal levels in men with undetectable blood FSH levels and urinary excretion of FSH less than that of prepubertal children. This conclusion implies that, although FSH may exert effects on human testicular function, maintenance of normal spermatogenesis and reinitiation of sperm production after short-term suppression by exogenous steroids can occur in spite of nearly absent FSH stimulation.

PMID: 6793629 [PubMed - indexed for MEDLINE]



Please notice that these guy where only on 200mg per week of test enanthate. And they got 5000 iu THREE TIMES A WEEK of hCG. Even at this level only two of the subjects returned to normal sperm count levels. The rest only got close. So it takes 15000 iu per week to get most men close to normal. What do you think 250iu will do?? Nothing is the correct answer.

This pubmed ariticle should be made a sticky because it directly relates to guys that are shutdown from testosterone use. You can find this article yourself by going to pubmed:PubMed Home
and inputing this number 6793629.

 

[BigRed66]

slin pins

 

[mma man]

Thanks guys you have been a big help

 

[dmc777]

There is a reason that hCG comes in vials of 5000 iu. That's the correct dosage!!! All the BS on line about doing 250 to 500 iu is crap. It was started by a guy that has a clinic called "All Things Male" He clams to be a leader in the field but has no articles published at all. He made some posts on-line with this bull shit way to use hCG and all it does is keep people coming back to his clinic.

If you put a little time into reading articles on pub med you will find out that nobody in the medical community follows this guys ideas.

Here is an article from pubmed where they studied normal men that had been shutdown from testosterone injection:

Follicle-stimulating hormone and human spermatogenesis.
Bremner WJ, Matsumoto AM, Sussman AM, Paulsen CA.

The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m. weekly to suppress luteinizing hormone (LH) and FSH, until three successive sperm counts revealed azoospermia or severe oligospermia (sperm counts <3 million/ml). Then, while continuing T, human chorionic gonadotropin (hCG) 5,000 IU i. m. three times weekly was administered simultaneously to replace LH activity, leaving FSH activity suppressed. The effect of the selective FSH deficiency produced by hCG plus T administration on sperm production was determined.Sperm counts (performed twice monthly throughout the study) were markedly suppressed during T administration alone (1.0+/-1.0 million/ml mean+/-SE, compared with 106+/-28 million/ml during the control period, P < 0.001). With the addition of hCG to T, sperm counts returned toward normal (46+/-16 million/ml, P < 0.001 compared with T alone). In two subjects, sperm counts during hCG plus T returned into the individual's control range. Sperm motility and morphology were consistently normal in all men during hCG plus T.Serum FSH levels by RIA were normal (110+/-10 ng/ml) in the control period and were suppressed to undetectable levels (<25 ng/ml) in the T alone and hCG plus T periods. Urinary FSH excretion was markedly suppressed in the T alone (60+/-15 mIU/h-2nd IRP, P < 0.01) and hCG plus T (37+/-9 mIU/h, P < 0.01) periods compared with the control period (334+/-78 mIU/h).We conclude that spermatogenesis as assessed by sperm counts, motilities, and morphologies may be reinitiated and maintained at normal levels in men with undetectable blood FSH levels and urinary excretion of FSH less than that of prepubertal children. This conclusion implies that, although FSH may exert effects on human testicular function, maintenance of normal spermatogenesis and reinitiation of sperm production after short-term suppression by exogenous steroids can occur in spite of nearly absent FSH stimulation.

PMID: 6793629 [PubMed - indexed for MEDLINE]



Please notice that these guy where only on 200mg per week of test enanthate. And they got 5000 iu THREE TIMES A WEEK of hCG. Even at this level only two of the subjects returned to normal sperm count levels. The rest only got close. So it takes 15000 iu per week to get most men close to normal. What do you think 250iu will do?? Nothing is the correct answer.

This pubmed ariticle should be made a sticky because it directly relates to guys that are shutdown from testosterone use. You can find this article yourself by going to pubmed:PubMed Home
and inputing this number 6793629.

Does anyone care to debate this? Nelson, Needto, Centeroiler....this is pretty good evidence. Are there any test showing the results of lower dosage hcg during cycle? This is interesting. I know that too much hcg can leave you permantely shut down though....wonder how much is too much and how long it can be run?

 

[swole]

great thread for on how to constitute HCG

http://www.elitefitness.com/forum/anabolic-steroids/help-hcg-584086.html