I got hardly any working seratonin (which regulates the sleep/wake cycle) left from constant x use on weekends. I find that 400mg of 5htp along with 1mg of melatonin taken before bedtime puts me right to sleep and it works very well. I think the less melatonin, the more effective. You can get 240 100mg 5htp pills for $21.00 at the online vitamin stores, other wise your gonna pay $13.00 for only 30 pills at the Walgreens.