Sister has MS Question

[wilson6]

Has she tried any of the HMG-CoA reductase inhibitors yet? That would be one suggestion as they seem to be very helpful with MS (turns down gamma-interferon).

Use fish oil, not omega-3 (alpha-linolenic), the conversion in humans isn't good at all.

W6

 

[THeMaCHinE]

Has she tried any of the HMG-CoA reductase inhibitors yet? That would be one suggestion as they seem to be very helpful with MS (turns down gamma-interferon).

Use fish oil, not omega-3 (linolenic), the conversion in humans isn't good at all.

W6

Fish oil does contain omega-3s. It's the omega-3 content of the fish oil (DHA/EPA) that works the magic. Fish oil omega-3s (DHA/EPA and just a little ALA) are long chain which is what the body utilizes well; omega-3s from plant sources (i.e. linolenic) are short chain, which have a conversion rate of about 1 to 5 percent.

 

[CrystalChick]

What is HMG-CoA reductase?
And Thank's sooooo much for the responces

 

[wilson6]

I meant to say alpha-linolenic (edited), I was thinking omega-3 and writing omega-6.

When I write on the boards, I define fish oil as fish oil even though it is omega-3. Many think of omega-3 as flax oil or alpha-linolenic vs fish oil 20:5n-3 or 22:6n-3 and think that omega-3 is omega-3.

As stated, the conversion of ALA via delta-6 desaturase is not good, thus fish oil has to be taken directly vs flax for example.

HMG-CoA reductase inhibitors are common cholesterol lowering agents such as Lipitor. The neurologist should be aware of this treatment.

W6

 

[THeMaCHinE]

I thought you probably had a reason for it. I like people to know that fish oil has a large omega-3 component to it (and that there are indeed different omega-3 fats), so they can talk about the subject in an informed manner. Especially since all of the successful omega-3 studies have been performed with fish oil, not flax, etc.

 

[CrystalChick]

MS she was on the Drip for three day's and started 80mg ED of Prednisone yesterday for 14 days.

 

[CrystalChick]

Bump

 

[fawnmarie]

Totally dumb, but anecdotal -

I ALWAYS get a salty taste in my mouth when receiving injections or getting blood drawn. Don't know why - always happens, always has happened. It is during the actual shots and for a little while afterwards.

Maybe it's a symptom or sideline of that subset of autoimmune diseases - I have fibromyalgia.

Fawn

 

[thebabydoc]

Oh BigEasy she was on methylprednisolone but the Dr. could not locate it anywhere Dexamethasone is supposed to be the substitute for it.

The dex(amethasone) is an acute treatment, like solu-medrol. And yes, there has been a shortage of methyprednisolone lately; it IS better but there are standard conversions between different types of steroids.