I usually start out at one dose of 25mg/200mg (E/C) for the first few days, then move it up to 2 doses by Thursday and Friday. I do a CKD, therefore, I usually do not take it on the weekends during my carb-up. By the time I am through with my dieting (weeks into the diet), I am taking 50mg Ephedrine, 400mg Caffeine, and a shitload of Yohimbine both topically and orally at about 3-4 times per day. Always work your way up, and if extreme doses are used, then it might be a good idea to get blood pressure check-ups to be on the safe side, at least I do about 2-3 times per month.
BMJ