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**Opinions needed does proviron hinder gains**

BIGEDD

New member
Lately I've been doing a lot of reading up on this stuff. I have used it throughout all three of my cycles as an anti e and to also keep my prince Albert working. But i hear so many different IMO's on this some say it blocks the receptors where gear attaches and I've even heard it will potentate your gear by making them bind more through smgb or something like that. Does anyone know for a fact if it does hinder gains?Because I've never not used !
 
Proviron is an androgen and thus binds to androgen receptors. It could be theorized that proviron could occupy a receptor that would be better used by an anabolic steroid, but it could also be said that high doses of testosterone increase AR population thus making availible enough AR's for everybody...proviron and AAS. It can also be speculated that proviron will bund to SHBG and free up more of the AAS for AR usage. So much debate, so few studies.
 
panerai said:
Does DHT hinder gains?
:)

Same as DHT, Proviron ezymatically gets converted to diol in muscles, which has very poor binding affinity to androgen receptor. It present no competition to other androgens.
 
I wish someone would cite some medical or scientific references that show proviron has antiestrogenic activity. One reads this all the time in the "underground literature'", but I have yet to see this claim documented by research.
 
I did a study on myself. It showed that I looked harder and bigger on proviron and felt better as well. Therefore, I conclude that proviron enhances gains by binding tightly to the SHBG and thus freeing up more exongenous test to be in the "free" state, causing better gains. I also concluded that I liked being horny as hell.
 
Dan Duchaine was an advocate of using Proviron with your cycles. Here's a quote:

...Proviron is rapidly reduced to inactive metabolites in muscle tissue, a trait characteristic of dihydrotestosterone, the belief that the weak anabolic nature of this compound indicated a tendacy to block the androgen receptor in muscle tissue, thereby reducing the gains of other more potent muscle building steroids, should likewise NOT BE TAKEN SERIOUSLY. In fact due to its extremely high afinity for plasma binding proteins such as SHBG, PROVIRON MAY ACTUALLY WORK TO POTENATE the activity of other steroids by displacing a higher percentage into a free unbound state." Anabolics 2000 p.157
 
I agree that Proviron increases muscle hardness by reducing estrogen-related water retension. Some users may have interpreted the anti-bloat action as reducing muscle size, and decided Prov works against AS. But no -- it only works against water bloat from Dbol and stuff like that.
 
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