Spartacus said:
passing this theory off as science
just one of you go through med school
and come back here
It is pretty clear what the long term use of steroids in women are:
From the March 2008 British National Formulary (this is the book of drugs that can be prescribed in the UK)
HRT increases the risk of thromboembolism, of stroke, and after some years, the risk of endometrial cancer (reduced by a progestogen) and of breast cancer. It is advised that the minimum effective dose should be used for the shortest duration.
Risk of breast cancer - ALL types of HRT increases the risk of breast cancer within 1-2 years of initiating treatment. The increased risk is related to the duration of HRT use (but not the age at which HRT is started) and this excess risk disappears within about 5 years of stopping.
10 in every 1000 women aged 50-59 not using HRT have breast cancer diagnosed over 5 years. In those using oestrogen only HRT for 5 years, breast cancer is diagnosed in about 2 extra cases in 1000 (about 6 extra cases over 10 years).
In those using combined HRT for 5 years, breast cancer is diagnosed in about 6 extra cases (about an extra 24 cases over 10 years).
Risk of endometrial cancer - increased risk of endmetrial cancer depends on the dose and duration of oestrogen-only HRT.
2 in every 1000 women aged 50-59 not using HRT have endometrial cancer diagnosed over 5 years. In those using oestrogen only HRT about 4 extra cases are diagnosed.
Risk of ovarian cancer - 2 in every 1000 women aged 50-59 years not using HRT have ovarian cancer diagnosed over 5 years. This figure rises by less than 1 extra case in 1000 in those using oestrogen only HRT.
Risk of venous thromboembolism - women on combined or oestrogen-only HRT are at an increased risk of deep vein thrombosis and of pulmonary embolism especially in the first year. This is about 2 extra cases in 1000 women over 5 years.
These women are typically taking 0.5-1 mg of oestrogen/day.
I could list more of the stats for slightly older women and combined therapy, but it is a lot of typing.
This is what is listed as the side effects for men on HRT
Prostate abnormalities and prostate cancer, headache, depression, gastro-intestinal bleeding, nausea, vomiting, cholestatic jandice, changes in libido, gynaemcomastia, polychythaeamia, anxiety, irritability, nervousness, astehrnia, paraesthesia, hypertension, electrolyte imbalance including sodium retention with oedema and hypercalcaemia, weight gain, increased bone growth, muscle cramps, arthralgia, androgenic effects such as hirsuitism, male-pattern baldness, seborrhoea, acne, pruritis, excessive frequency and duration of penile erection, precosious sexual development and premature closure of the epiphysis in pre-pubertal males, suppression of spermatogenesis in men and virulisation in women; rarely
liver tumours, sleep apnoea also reported; with patches, buccal tablets and gel local irritation and allergic reactions (including burn-like lesions with patches) and taste disturbances.
Doses
Oral
120-160 mg daily for 2-3 weeks, maintainance 40-120 mg daily
Intramuscular
250 mg every 2-3 weeks, maintainance 250 mg every 3-6 weeks
This is the medical use of sex steroids for clinical conditions.
Know the risks, and what you are willing to live, risk or not risk.
It's your body, you only get one, take care of it.