macrophage69alpha
New member
Hooker (thats your real name anthony- so that people know who you are)
1. do you actually have a legitimate question?
2. actually the merck manual is pretty useless compared to many other texts and is available in its entirety online-btw- do have a copy it and of the PDR, but since they both say that anabolic steroids do not increase muscle mass, have not looked at them in about 10 years. Have not bought a copy since though do have the current third edition herbal PDR.
3. as noted the merck manual has no information on ATD
4. What the pharmaceutical industry uses and whats available are not the same. The method used by pharma is designed for convenience and patentability. The use of HPMC (patch and gel) decreases bioavailibility but extends release. once daily is what they want because people are lazy. Besides the fact that the Isolated PE's that they use are patentable, the organic PE's which are more effective, like orange oil and variants of tea tree oil are not.
5. With respect to steroids and transdermal delivery, the issue is COST and AVAILABILITY. while the cost of steroids is typically cheap, the end user often has a much higher cost and less availability. Plus ester technology is widely used, so injection is the preferred route- which gives 100% bioavailibility- minus the ester weight.
1. do you actually have a legitimate question?
2. actually the merck manual is pretty useless compared to many other texts and is available in its entirety online-btw- do have a copy it and of the PDR, but since they both say that anabolic steroids do not increase muscle mass, have not looked at them in about 10 years. Have not bought a copy since though do have the current third edition herbal PDR.
3. as noted the merck manual has no information on ATD
4. What the pharmaceutical industry uses and whats available are not the same. The method used by pharma is designed for convenience and patentability. The use of HPMC (patch and gel) decreases bioavailibility but extends release. once daily is what they want because people are lazy. Besides the fact that the Isolated PE's that they use are patentable, the organic PE's which are more effective, like orange oil and variants of tea tree oil are not.
5. With respect to steroids and transdermal delivery, the issue is COST and AVAILABILITY. while the cost of steroids is typically cheap, the end user often has a much higher cost and less availability. Plus ester technology is widely used, so injection is the preferred route- which gives 100% bioavailibility- minus the ester weight.