Fast Twitch Fiber said:
"I have found that my receptors don't stay fresh with the HRT so when I start a cycle I don't get the dramatic growth. However, I keep more of the gains afterward. Maybe I just need to bump the dosages up on my cycle to get good gains."
I have found the same thing to be true about the receptors. I am on HRT and find that I do not gain much "on cycle" either. On the other hand, I pretty much keep everything that I gain as a rule, however little that is. In order to try to counteract this, I did try very high doses on cycle in the past(at least for me) at 1.2 gram/week of test and 1.2 gm/week of deca. The result is that it was a waste of material and didn't work any better than say 400mg/week of test and 200mg/week of deca for a cycle IMO. Since I get my deca and test by legal scrip for known medical conditions, I know that they are real and they are U.S. made pharmaceuticals hence "real." So I also suspect that HRT tends to "deaden" the receptors over time. Incidently, even at high levels, my estrodiol levels are mid normal range and I have never had the slightest propensity towards gyno--don't ask me why since I have no idea. Consequently, I have never used any anti-e's. I also find that even 50 mg/day of Oxandrin stacked on top of deca and test doesn't even phase me. I also notice that above "replacement levels" there is a distinct lessoning of libido so I agree that there is clearly an optimum blood concentration for me as well.
The ONLY thing that seems to overcome the "deadening" of the receptors for me from my experience is Fina. I tried it at 75 mg ED for eight weeks on a recent cycle stacked on top of test and it was almost miraculous. I tried it because it supposedly has three times the binding affinity for receptors as does testosterone so I suspected it might be the "missing piece." For the first time ever, I gained 15 lbs on cycle, cut in at the same time and kept it all. Just as a note, I have lifted weights for 29 years and my pre HRT and pre use of ANY anabolic agents size weight was 227 lbs at 5'11.5" tall. Currently, I am between 245 lbs and 250 lbs with single digits for bodyfat.