IGF-1 insulin like.

[KA-BAR]

Just wanted to get opinions of this stuff. Ive been reading what el cubano said about this stuff and i thought I would give it a try but im not sure on dosage. IGF-1 is measured in mgs not ius, each 1mg equates to 1000mcg. So im thinking one would need to take 50 - 100mg a day right? Is this stuff as good as slin? Also what is the difference between media grade and receptor grade?

1mg media grade
10mgs media grade
5mgs receptor grade
10mgs receptor grade

 

[KA-BAR]

bump

 

[embolicintent]

I can't answer your question but...

I was intrigued by this post because the use of IGF-1 in bodybuilding is new to me. I can tell you what I know about IGF-1 from med school which is dated a few years though.

Growth hormone effects are primarily mediated through Insulin Like Growth Factors. I know a very little amount about IGF-1 and IGF-2 and little else. The insulin like growth factors got their name because their struture is very similar to the structure of the pro-insulin molecule before its enzymatic splitting. The molecules were discovered by Salmon and Daughaday some 40 years ago when they discovered that Growth hormone alone could not cause cartilage growth in a laboratory, but that in animals GH produced proteins that could cause cartilage growth in a laboratory by themselves i.e. IGF's. IGF-1 was originally called somatomedin. The cell receptor for IGF-1 is a tyrosine kinase receptor that is remarkably similar to the insulin receptor. IGF-1 is produced in most tissues of the body where it effects cells locally, but the major blood concentration comes from the liver which is a major production site.

As far as effects, IGF-1 has been shown to not only enhance cartilage growth, but also to increase hematopoiesis and cell differentiation. It also has effects on eye lens differentiation. In adult human testing, IGF-1 was shown to increase nitrogen retention and decrease blood urea nitrogen (BUN) levels. It is also proven to stimulate growth without the presence of GH. In fact increased levels of IGF-1 have a negative feedback onto GH decreasing blood levels. However, GH stimulates production of IGF-1. Thus in summary IGF-1 is the workhorse of GH. It is resonsible for many of the effects that GH takes credit for. In reality GH's effect i to increase IGF-1 which really does the work.

As for dosing etc.. I wouldn't have a clue. I can tell you that the normal adult levels are between around 100-500 micrograms/liter whereas in puberty at which time IGF-1 levels are at their lifetime peak, levels range around 200-960 micrograms/liter.

I know that this is long and not what you really wanted to know, but I hope it is useful info.

 

[KA-BAR]

so basically my ears and nose will grow along with everything else right? lol

 

[ripper2]

all the dosing schemes i've seen have shown from 20mcg/day up to 100mcg/day taken after working out.

 

[pajaro loco]

HOW MUCH DOES THIS COST?

 

[KA-BAR]

10mgs media grade $800 - 30% if you get bulk price $560 and that is alot of stuff.

 

[40butpumpin]

Interesting post, embolicintent. This sounds interesting to me.

 

[Lift Chief]

The information and studies i've read on IGF-1 was similar to what i've read on hGH. It should work in theory, but in practice you don't get very good results.

Unless you're hell-bent on becoming a pro i don't see why you couldnt just stick with test/fina/dbol...IMO.

Bump though for any first hand accounts.

 

[the nature boy]

ask fonz, he'll be able to tell you.