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HGH Injection timing - Plunkey get in here

ok so I completely understand your point about hgh levels being a moving target, I've known that and that's why it's hard to test for GH use in sports cause you basically have to catch it within 20-30 minutes of secretion because it's pulsatile and random.

So first let me explain the math I did earlier, I may be wrong I acknowledge this. But when I researched average GH levels in normal humans I found that "generally" they say 20 year olds make about 500 micrograms a day and by 40 we're making 200-250. So I put myself at 400 micrograms because I've been lifting at 90%+ intensity since I was 20 and that's where they say lifters make the most GH..when they're operating as close to their 1 rep max as possible. I also read that 1mg of GH equals about 2-3 Iu's. This is where I may be off I don't know, it's kind of nebulous from what I've read on the internet. So again, I may be introducing a lot of errors.

Now, the fasting study. The researchers made the statement that detecting accurate GH levels in people is very difficult because of what we talked about before. But detecting GH levels in fasting people is "easy"...because at about the 12 hour mark the body goes into continuous production. So their top end of the study was 2000% more GH production over average baseline. So I took 400 micrograms and multiplied it by 2000%. That's a lot of fucking GH, more than any sane person would want to inject synthetically. But this is also biological compatible GH, obviously, so it isn't going to make one of your organs randomly grow an extra wing because that GH is being metabolized for specific purpose's. The reason I'm fairly confident that I'm "at least" at that 2000% mark is because I'm also weightlifting in the fasted state. That took some getting used to no question, I'm still adapting to it. So if they saw 2000% increases at the top level in their subjects who weren't doing "any" strenuous physical activity....I've got to be "at least" at 2000%.

This is where I"d like to compare notes with you. Prior to starting this diet I had "ridiculous" joint problems with my shoulders and my back. You remember me talking about my back, you've trolled me on more than one occasion about it. But honest to god swear on the Spellwin himself my back hasn't even tweaked since I started this, it's been at least 6 months now, maybe more. There wasn't a single upperbody wkt during the week where I wouldn't walk out of the gym with an ice bag on one of my shoulders. It was just ritual. Went on for easily 2 years. The back would also tweak with regularity, sometimes really badly where I could barely move for a day or two. All of this was just systemic inflammation. It got "slightly" better when I went to the vegetarian diet but it didn't go away. I've known for awhile now that when I fasted shit healed quicker. But I never contemplated working out in the fasted state. So you've been doing this synthetically for 9 years, what is the difference in recovery and joint issues?

Even though I'm done with roids, GH supplementation is still something I'd consider in the future even though I appear to be fine on that front. It may be beneficial to do a couple months out of the year to give your pituitary a break, I don't know. I think that because I read a study that said low dose testosterone therapy actually makes your natural levels come back hard afterward. They did a study on some older men...lot older than you actually. For one night only I'll admit you're in your mid 40's. These guys were all in their 50's if I remember correctly and their natural T levels came back virtually to that of 20 year olds because the supplementation allowed their hpt axis to take a breather.

I hope you read this and don't dismiss it outright just cause it came from me. There's some significant studies on caloric restriction and/or timing that are fascinating to me and this isn't some hippy bullshit that you like to paint me with. The body does some fascinating shit when fasting like completely shutting testosterone down and making growth hormone, norpenipherine, insulin, adrenaline..stuff like that. The reason is because it's priming us for war, or hunting whatever. Basically physical combat. Than after we have that meal, those chemicals get shut down and we make massive amounts of testosterone. I don't care what anybody say's that's fascinating as fuck to me. All those hormones that keep us young and strong are made when we're not eating. Testosterone is basically just the fuck hormone, nothing more....there to give us the urge to procreate.

I don't know much about HGH production and fasting. For me personally, I haven't associated much of a change in GH production with diet and/or weight.

As far as making 500 micrograms a day at 20 years old, that would be 3.5 mg (10.6 IU) per week which sounds low. There may be some efficiencies associated with natural versus exogenous HGH and I don't know how much of the dose gets broken upon delivery (I suspect it's more than they admit).

For the 40 year old example, 200 micrograms/day = 1.4 mg/week. Then assume you need somewhere between 0.8 to 1.6 mg per day on five out of seven days to get back to high-normal levels. That puts you at 4.0 to 8.0 mg/week of exogenous HGH.

Here's another datapoint to check. For children with HGH deficiency, dosing guidelines are 0.025 to 0.043 mg/kg/day. So for 80 lb kid, we're talking about 0.91mg to 1.56mg per day. But those are done seven days a week (I believe), so you'd be at ~11 mg per week maximum. So far, the studies show that these kids have no adverse long-term effects.

Here's why I'd question the 2000% (20x) impact. At 400 micrograms/day, you'd be making 2.8mg per week. But even if you were at the 20x level for only 25% of the time (8 hours/day) on average, you'd be at 2.8 + 25%*2.8*20 = 16.8mg per week. That's high -- comfortably above the maximum guidelines for dosing children (but you do also weigh considerably more than they do). I suspect (no citationing here) that you'd down-regulate your own production before your body would make that much.

And I would keep an eye on the weightlifting and HGH linkage. There's no doubt the lifting increases HGH when compared to sedentary people -- but the lifting/HGH curve flattens-out and starts to drop again past a certain point. I would bet a lot of people who workout at higher intensities are past (sometimes far past) that optimum point.

And when it comes to the impact of HGH, its really best to periodically get some IGF-1 bloodwork at regular intervals and just test it for yourself. Then you'll get a feel for how the number is just all over the board.
 
knot so easily

I'm all butt hurt now

I'll make it up to you.

We'll coordinate costumes for the Cutter's "Anything Goes" dress-up night.

I'll dress up as a rocket and you can go as Uranus.
 
Plunked - do you work out in the morning after your injection?

I've moved my workouts from the mornings to noon (at work).

My mornings are now tied-up chasing twins between 7:00 and 7:30 because they're typically asleep before I get home.
 
I've moved my workouts from the mornings to noon (at work).

My mornings are now tied-up chasing twins between 7:00 and 7:30 because they're typically asleep before I get home.

ok.. my problem is with carbs and hgh. I usually do HGH, have a small energy drink, then do about 1 hr cardio / light weight workout.

Now I am thinking I must skip the energy drink or wait 45 minutes between pin and drink. Thoughts??

It is more or less a green tea/ ephedra drink with some cane sugar in it. About 60 calories in total.
 
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ok.. my problem is with carbs and hgh. I usually do HGH, have a small energy drink, then do about 1 hr cardio / light weight workout.

Now I am thinking I must skip the energy drink or wait 45 minutes between pin and drink. Thoughts??

It is more or less a green tea/ ephedra drink with some cane sugar in it. About 60 calories in total.

I run into the same problem with my preworkout drinks -- and the post workout ones can be even worse.

So for me, injecting in the morning and holding-off on breakfast for an hour works. And based on what I've heard and read, a pre-workout drink would be a bad combination with an HGH shot.
 
if you work out at noon wouldn't you want that GH shot right after? Years ago I did IGF and the protocols were usually as PWO as possible.
 
ok ... last comment here.

My first bloods looked like this
IGF 1 = 121 ng/ml
Test = 686 ng/dL
Free Test = 15 pg/mL
Estradiol = 32.7 pg/mL

6 week follow up

IGF 1 = 199 ng/mL
Test = 911 ng/dL
Free Test = 21.2 pg/mL
Estradiol = 26.5 pg/mL


Now out of that they only thing they increased was adding another day of HGH injection. If IGF1 is at the top of the range, does that make sense?
 
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