I've never understood or used IGF-1 directly. My only experience is watching IGF-1 levels fluctuate with varying doses of HGH.
I was kind of wondering this below, but in simplified terms. Like, I get it on the surface level, but I know there's a ton going on behind the scenes that I just don't understant or know. I really need a first-year text on endocrinology. (Hey, Chris, got one?)

Kidney International - Figure 3 for article: Chronic renal disease: A growing problem
