I haven't used creatine in a long time, but there have been at least a couple recent studies showing increased benefit by cycling it. I can't recall what the optimal on and off periods were found to be off the top of my head though.
I have heard that if you don't come off it or cycle, then your body will lose the ability to use it efficiently or transport it. It seems like there is a little bit of uncertainty in some of the findings done by different researchers.
I haven't used creatine in a long time, but there have been at least a couple recent studies showing increased benefit by cycling it. I can't recall what the optimal on and off periods were found to be off the top of my head though.