Bulldog_10 said:Can you, by any chance, explain how deca helps joints? I know you're big on this, that's the only reason I ask. Just doesn't make sense to me, but I guess everyone can't be wrong.
If I could answer that the Nobel Prize may be waiting for me. The studies showing that deca improves spinal injuries and gives pain relief don't offer an explanation. They only note that it works and they give theories. Almost all were done on women with spinal fractures (crushing type) so they have abandoned it because if the sides women get from it. There is no data on men that I know of.
Clin Rheumatol. 1995 Sep;14 Suppl 3:32-9. Related Articles, Links
Nandrolone decanoate: pharmacological properties and therapeutic use in osteoporosis.
Geusens P.
Arthritis and Metabolic Bone Disease Research Unit, Katholieke Universiteit Leuven, Pellenberg, Belgium.
The therapeutic profile on bone of nandrolone decanoate is that of inhibitor of bone resorption with temporary increase in bone formation, followed by an absence of suppression of bone formation, indicating uncoupling of bone resorption and formation. This results is an increase in bone mineral content at the proximal and distal radius, and in some patients at the lumbar spine. Furthermore, nandrolone decanoate increases calcium balance and muscle mass, diminishes vertebral pain and increases the mobility of the spine. Virilization occurred in around 50% of the patients (mainly hoarseness and/or hirsutism), and 9% of the patients dropped out because of this reason. A dose of 50 mg every 3 to 4 weeks is indicated in the treatment of osteoporosis in women, especially when they have low muscle mass, associated debilitating disease, and in patients with corticosteroid induced osteoporosis.
More to look up...
Bone Miner. 1994 Dec;27(3):209-17.
Effect of nandrolone decanoate and 1-alpha-hydroxy-calciferol on patients with vertebral osteoporotic collapse. A double-blind clinical trial.
Lyritis GP, Androulakis C, Magiasis B, Charalambaki Z, Tsakalakos N.
J Bone Miner Res. 1994 Feb;9(2):277-83.
Course of bone mass during and after hormonal replacement therapy with and without addition of nandrolone decanoate.
Erdtsieck RJ, Pols HA, van Kuijk C, Birkenhager-Frenkel DH, Zeelenberg J, Kooy PP, Mulder P, Birkenhager JC.
Maturitas. 1989 Sep;11(3):187-97.
Effects of nandrolone decanoate therapy on bone mass and calcium metabolism in women with established post-menopausal osteoporosis: a double-blind placebo-controlled study.
Gennari C, AgnusDei D, Gonnelli S, Nardi P.
Arch Intern Med. 1989 Jan;149(1):57-60.
Effects of nandrolone decanoate and antiresorptive therapy on vertebral density in osteoporotic postmenopausal women.
Need AG, Horowitz M, Bridges A, Morris HA, Nordin BE.