Even a .22 cal can stop an intruder. I should have said "more stopping power". I've studied the statistics. Most shootouts end in 4 or 5 rounds. .357 magnum and .45 cal have the highest percentage of one shot stops. The 9mm is usually around 115 grains. A .45 cal is usually around 230 grains. It's has much more impact. If I miss center and put a 9mm round in somebody's leg, they can still move. If I miss center and put a .45 cal in somebody's leg, they are more likely out of action.
I do like the Glock 19 longslide, buy haven't shot it. I like that 9mms hold more and the ammo is much cheaper. The deciding factor is that I feel comfort with the kick of the .45 cal. I shot it more accurately at 30 feet than the 38 special at 20 feet.
I take it you are suggesting the Glock 19. I'll see if they have one to rent at the range.