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Will steroids slow down my bones from healing?
- Thread starter E-Rawk
- Start date
Testosterone, androstenedione, DHEA, and estrogen all play roles in bone development and maintenance.
The only synthetic androgen (that I have read) used in studies that showed positive proliferation of osteoblast cells (the cells that build bone) was halo.
Estrogen too plays a pivital role.. In fact, there are two documented cases of males with mutant ER's.. Both died before the age of 20. I'm not 100% sure how much of a role estrogen plays in maintenance of bone, but it is very important in development.
Corticosteroids and thyroid hormones have a negative effect on bone development.. So stay away from t3.
I would say as long as you have some test, you will be fine and probably even heal faster.
But like i said (other than halo) I don't know if other AAS have the same bone building properties of test.
Andy
The only synthetic androgen (that I have read) used in studies that showed positive proliferation of osteoblast cells (the cells that build bone) was halo.
Estrogen too plays a pivital role.. In fact, there are two documented cases of males with mutant ER's.. Both died before the age of 20. I'm not 100% sure how much of a role estrogen plays in maintenance of bone, but it is very important in development.
Corticosteroids and thyroid hormones have a negative effect on bone development.. So stay away from t3.
I would say as long as you have some test, you will be fine and probably even heal faster.
But like i said (other than halo) I don't know if other AAS have the same bone building properties of test.
Andy
After a quick search on medline, the only studies i could find were based on rats and guinea pigs. But the theory holds true.....here is a quick cut and paste...
The conclusion of this study is that an agent with a low androgenic activity does not increase calcium callus concentrations early in the course of fracture healing compared to an agent with higher androgenic activity. As healing progresses, both agents increase the concentration of calcium in osteotomy healing. The clinical significance of this study is that agents with low androgenic activities favorably influence osteotomy healing and may be clinically useful because they lack unwanted virilizing activity.
But the fact remains that if you stress the bone before it is completely healed, you run the risk of injuriing yourself again. If you are only doing legs, then go for it. It takes bone about 8-12 weeks to heal, so if you can hold out that long go for it. If not, then save your gear for later. Your surgeon may want to check an X-ray of your hand in about 6-8 weeks to see how the bone callous is forming and/or then another after 10 weeks to see if the callous has resorbed and healing is almost complete. You will feel pain if it isnt healed and you start to lift again.
btw.....thanks for the props
T
The conclusion of this study is that an agent with a low androgenic activity does not increase calcium callus concentrations early in the course of fracture healing compared to an agent with higher androgenic activity. As healing progresses, both agents increase the concentration of calcium in osteotomy healing. The clinical significance of this study is that agents with low androgenic activities favorably influence osteotomy healing and may be clinically useful because they lack unwanted virilizing activity.
But the fact remains that if you stress the bone before it is completely healed, you run the risk of injuriing yourself again. If you are only doing legs, then go for it. It takes bone about 8-12 weeks to heal, so if you can hold out that long go for it. If not, then save your gear for later. Your surgeon may want to check an X-ray of your hand in about 6-8 weeks to see how the bone callous is forming and/or then another after 10 weeks to see if the callous has resorbed and healing is almost complete. You will feel pain if it isnt healed and you start to lift again.
btw.....thanks for the props
T
more.....
Several investigations have documented that the use of anabolic agents could promote osteogenesis and enhance bone ingrowth in traumatized bone. Previously, anabolic steroids have been shown to increase the mineralization of bone. However, their clinical use has been limited because of the unwanted virilizing activity. The previous studies used systemic administration of anabolic steroids, which subjects other tissues within the body to high concentrations of hormones. In addition, different anabolic/androgenic steroids have varying affinities to different cell types within tissues. The specific objectives of this study were (i) to histopathologically evaluate the structural changes associated with sustained delivery of testosterone (T), dihydrotestosterone (DHT), and androstendione (AED) using adult male rats as a model, and (ii) to morphometrically evaluate the cortical areas and length upon the exposure of the aforementioned hormones for 90 days. A total of 23 adult rats were randomly divided into five groups (group I = control, group II = sham, group III = AED, Group IV = T and group V = DHT treated). At the end of the treatments the animals were euthanized and the x-rays, blood, and bones were analyzed using standard laboratory protocols. Data obtained from this investigation revealed the following: (A) all treated femurs appeared healthy with no traumatic responses observed in comparison to control animals, (B) measurements of the inner perimeter of the bone on the endosteal side showed significant reduction in the androgen treated animals. This suggesting that the androgens caused increases in the cortical bone. The differences seen in the amount of reduction was in the following ease: T > DHT > AED. C) quantitative measurements of the cortical length showed slight increases in the cortical lengths in the androgen treated rats in comparison to the control.
So these guys are right in that it will help your healing most likely. Dont get overconfident though. The hand is the biggest pain in the ass cuz you are always using it. My own hand injury has taken more than 2 months to heal so that i cant torque it at all or swing a baseball bat without it starting to hurt again. My injury is purely ligamentous/tendon injury, not a fracture. Soft tissue injuries sometimes take longer to heal than bone. I just started lifting again with very little or no pain this month.
The biggest difference between our injuries is that my soft tissue will "tear" or stretch little by little if i overstress it. Your bone will most likely break suddenly without too much warning.
T
Several investigations have documented that the use of anabolic agents could promote osteogenesis and enhance bone ingrowth in traumatized bone. Previously, anabolic steroids have been shown to increase the mineralization of bone. However, their clinical use has been limited because of the unwanted virilizing activity. The previous studies used systemic administration of anabolic steroids, which subjects other tissues within the body to high concentrations of hormones. In addition, different anabolic/androgenic steroids have varying affinities to different cell types within tissues. The specific objectives of this study were (i) to histopathologically evaluate the structural changes associated with sustained delivery of testosterone (T), dihydrotestosterone (DHT), and androstendione (AED) using adult male rats as a model, and (ii) to morphometrically evaluate the cortical areas and length upon the exposure of the aforementioned hormones for 90 days. A total of 23 adult rats were randomly divided into five groups (group I = control, group II = sham, group III = AED, Group IV = T and group V = DHT treated). At the end of the treatments the animals were euthanized and the x-rays, blood, and bones were analyzed using standard laboratory protocols. Data obtained from this investigation revealed the following: (A) all treated femurs appeared healthy with no traumatic responses observed in comparison to control animals, (B) measurements of the inner perimeter of the bone on the endosteal side showed significant reduction in the androgen treated animals. This suggesting that the androgens caused increases in the cortical bone. The differences seen in the amount of reduction was in the following ease: T > DHT > AED. C) quantitative measurements of the cortical length showed slight increases in the cortical lengths in the androgen treated rats in comparison to the control.
So these guys are right in that it will help your healing most likely. Dont get overconfident though. The hand is the biggest pain in the ass cuz you are always using it. My own hand injury has taken more than 2 months to heal so that i cant torque it at all or swing a baseball bat without it starting to hurt again. My injury is purely ligamentous/tendon injury, not a fracture. Soft tissue injuries sometimes take longer to heal than bone. I just started lifting again with very little or no pain this month.
The biggest difference between our injuries is that my soft tissue will "tear" or stretch little by little if i overstress it. Your bone will most likely break suddenly without too much warning.
T
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thanks bro, great info. I dont plan on stressing it till its fully healed. I injured it very seriously. The cycle really isnt to speed up healing but just to keep mass on upper as much as possible and build a little down low. As long as i'm not hindering the healing process then i am happy.
Steroids will slow bone growth just as it will lower your immune system. However they will help you post surgery for recovery as in tissue, strength, keeping weight. I broke my arm and had to have a plate put in it. I was given this big speech from my specialist about steroids and he gave me stuff to read that explains it. don't remember but it will slow actual bone growth.
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