Prostate cancer from test. ALL MUST READ!

[MisterX]

I

 

[Realgains]

Dudes high DHT levels are still considered by most Urologists to be one cause of prostate Cancer and not just something that makes it worse once you've got it!

Ask a Urologist why he gives Finasteride to those with benign prostatic hypertrophy. He gives it so the patients can pee, BUT more importantly he orders it to inhibit DHT and reduce the benign hypertrophy which often converts to CANCER!!!

 

[panerai]

Actually, nandrolone has a stronger binding affinity than even DHT. However, in the prostate, most of the nandrolone will be converted via 5AR into a less harmful metabolite (if finasteride is not used).

No way! Nandrolone's binding affinity to AR in prostate is about the same as Testosteron, that's why after 5-alpha reduction Test is becoming approx 3 times stronger DHT and Nandrolone approx 3 times weaker DHN.
If, to begin with, Nandrolone had as strong binding affinity as DHT, how much of reduction would be needed to reduce it to so much less androgenic metabolite?

BTW, Trenbolone has approx same binding affinity to AR as DHT.
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Different patterns of metabolism determine the relative anabolic activity of 19-norandrogens.

J Steroid Biochem Mol Biol 1995 Jun;53(1-6):253-7 (ISSN: 0960-0760)

Sundaram K; Kumar N; Monder C; Bardin CW [Find other articles with these Authors]
Center for Biomedical Research, Population Council, New York, NY 10021, USA.

Testosterone, the principal androgen secreted by Leydig cells, exerts a wide range of actions including growth of the male reproductive tract (androgenic effects) and growth of non-reproductive tissues such as muscle, kidney, liver, and salivary gland (anabolic effects). As androgenic steroids were discovered some were found to have relatively more anabolic than androgenic activity. The results reviewed in this report suggest that these differences result, in part, from the differential metabolism of the steroids in individual tissues and the varied activities of the individual metabolites. In the accessory sex organs (e.g. the prostate) testosterone is 5 alpha-reduced to dihydrotestosterone (DHT) which, due to its higher affinity for androgen receptors (AR), amplifies the action of testosterone. In contrast, when 19-nortestosterone (NT) is 5 alpha-reduced, its affinity for AR decreases, resulting in a decrease in its androgenic potency. However, their anabolic potency remains unchanged since significant 5 alpha-reduction of the steroids does not occur in the muscle. 7 alpha-methyl-19-nortestosterone (MENT) does not get 5 alpha-reduced due to steric hindrance from the 7 alpha-methyl group. Therefore, the androgenic potency of MENT is not amplified as happens with testosterone. These metabolic differences are responsible for the increased anabolic activity of NT and MENT compared to testosterone. Part of the biological effects of testosterone are mediated by its aromatization to estrogens. The fact that MENT is also aromatized to 7 alpha-methyl estradiol, a potent estrogen, in vitro by human placental and rat ovarian aromatase suggests that some of the anabolic actions of MENT may be mediated by this estrogen.
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[mrt]

So, is it a good idea to use Finasterid 1mg EOD for preventetive reasons in cyccle of Test or should we use ED as it's prescribed?

 

[wilson6]

If you're worried about prostate cancer and juice, then have a PSA and digital exam done every 6-12 months. Don't count on Saw Palmetto or Proscar to save your ass.

Know what's going on and catch it early if it happens. However, if there were a clear link between juicing and early prostate cancer, we'd have seen the numbers by now and thus far, it is still pretty rare.

W6

 

[MuSuLPhReAk]

Great thread!

 

[Maxx Out]

i dont ever get gyno so iam not worried about gyno too much..

Lucky Bastard!!!

Actually, I guess you're ULTRALUCKY!!


Maxx >>>>>

 

[MrLoVeRlOvEr]

ok a simple question..

if using deca do i need finaside

 

[eric88]

why have i never seen finasteride on any price list from any of my dozen sources?does it have a generic name?

 

[NORMA-MAN]

why have i never seen finasteride on any price list from any of my dozen sources?does it have a generic name?

finasteride is the generic name.....
brand name is propecia/proscar