Prohormones: The Real Deal

[Bill Llewellyn]

didthey ever methylate nordiol or 1-test?

19-nor-5-androstenediol was methylated, and came out 7 times more anabolic than MT, and 1-Test was methylated to be 16 times more anabolic, by the best oral assay, than MT.

- Bill

 

[pa1ad]

I have never crossed that particular steroid, but that doesn't mean it hasn't been done. Its existence however is academic anyway. I don't expect you will ever see such a compound sold as a nutritional supplement.

Dimethyl? What does he mean by Dimethyl?

 

[pa1ad]

Well i would like to hear PA'S take, but using logic methyl-4ad was obviously crappy and not potent or it would have been a pharmaceutical, because they loved to release orals.

Also obviously the reason they never methylated any other PH because after methyl4ad was so bad there was no reason to methylate others

and lastly according to animal in a old post he wrote 2 years ago any PH has to be dimethylated because it can't physically be single methylated and even if somehow it could be it would be incredibly hard and costly to manufacture

methyl 4-AD actually assayed out very well. BTW, many very effective potential drugs never made it to market. thousands and thousands

the animal comment is the biggest piece of idiocy i have read on the net in a long time. He has absolutely no idea what he is talking about.

You want to make methyl 4-AD? Hydride reduction of methyltestosterone.

 

[pa1ad]

Oh boy, here we go again. I am looking at a book right now with literally hundreds of orally active steroids that were never sold.

[/B]

Firstly they were not looked at as methylated prohormones, but other methylated steroids. In the case of Methyl-4-AD it is no doubt significantly more potent than 4-AD because it has a much longer half-life. It is not the most potent steroid in the world, but probably far from terrible. I've never used it so I can't say, but you are certainly not making valid arguments.

[/B]

He was probably talking about di-esterified or di-etherified prohormones, as I would think it very difficult to attach esters or ethers to only one of the two hydroxyl groups on a diol hormone. 4-AD-EC is actually 4-AD-DI-EC. But that looks a little to funny for marketing purposes...

- Bil [/B]

It is not that difficult. If you want to make 4-AD monoEC for instance you just make testosterone EC and then reduce the 3-OH group using a technique which won't attack the ester.

 

[pa1ad]

But you even said they never lab assayed it ,the reason probably because it was garbage

And someone asked animal specifically about METHYLATED ph he said it has to be dimethylated no other way it would work, and methylatylating anythign is very hard and expensive

didthey ever methylate nordiol or 1-test?

MikeRaz you really have no idea what you are talking about. No offense. There is data on 17alpha methyl 4-AD and it is relatively potent. It did not have a good anabolic androgenic index however.

Methylating an androgen is not expensive and is basic chemistry. No, animal cannot do it in his kitchen (I guess this is why he considered it difficult), but most chemistry is done with specialized equipment, not pots and pans.

They did methylate 1-test. See last edition of muscle monthly print magazine where i mentioned it. It is very potent.

I am sure someone made a methyl nor-4-diol, but I don't recall seeing any assay information

 

[pa1ad]

i love it when mikeraz throws ouit shit and then gets beaten by bill and pa its more entertaining then Survivor

but on a serious note bill on top yo mentioned that methyl4ad assayed out significantly less androgenic then mt isnt that similar to how dbol assayed out?

No. this compound assays out more androgenic and more anabolic than methyltest

 

[pa1ad]

wonder why they never lab assayed it , any chance maybe they did but didnt publish

Kem. Ind., 1975, 24(7), 392-4

Its in Serbo-Croatian

 

[MIKERAZ]

First off thankyou for your response PA i do Respect your work and deem you very knowledgable and innovative but

What animal meant by dimethyl when asked about methy-ph he said the only way to methylate a Ph is by dimethylation same way you can only di-esterfy it (such as di-proprienate) and it was not worth it because he never read anyhting about dimethyl steroids being potent

Juust because something assays out ok doesnt mean it will work for muscle growth in humans

And you even said the reason it never went anywhere because it had a horrible androgenic/anabolic index meaning it sucks for muscle growth and isnt potent ,also you stated it was relativly potent, relativly means not very, the steroids released to market were not relativly potent they were very very potent.

Where can i find your write up on methyl1-test?

 

[notpuff]

whats the diffrence between a assay and index?

 

[Bill Llewellyn]

No. this compound assays out more androgenic and more anabolic than methyltest

Different references I'm sure. I'm looking it up in Vida, since I've had my face in it so much lately.

- Bill