Should probably clear a few things up and this goes for anyone contemplating " Lifelong " TRT. First and foremost no and I mean no one should consider this without having it fully endorsed and administered by a qualified Doc( endo pref. ). Assuming you have had every battery of blood work done, full physical etc and of course your T levels are low to the point where your Doc recommends it then yeah it can be a positive life changing event. Low T levels particularly in older men have all sorts of neg. effects on the body. Libido, mental focus, depression and osteporosis. For every study that says TRT for long periods of time are harmful I can show you just as many from the most credible Universities in the world that will state the opposite. I have gone to a dozen Doctors, many of whom believe that low t-levels are one of the most underdiagnosed problems facing aging men today. If your truely experiencing the effects of low T I dont know why anyone wouldnt want to go on TRT for a better quality of life. Are there risks? sure but ask yourself if it outweighs the risks of having low T. Dont use Arnold as an example, I can tell you that at his age he does NOT look good at all. Now sly, Lou F and others look amazing for their ages. Bottom line is that at the moment TRT, HGH used correctly are about the best " Fountain of youth " chems at our disposal. Of course the medical community will NEVER tell you that for a thousand reasons I wont go into right now. Good Luck!