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Input on PCT

alphatest said:
I mean no disrespect but there is a good reason medical studies don't rely on anecdotal evidence. Don't you think it is just a little silly to claim that user feed back on message boards trumps everything else. Especially when the studies in question on are done on real live users.

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AND THE PEOPLE MENTIONED AREN'T REAL AND LIVING? LOTS OF THINGS WRONG WITH THAT STUDY .




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I never claimed it was the greatest. This board seems to hold PP's products in high regard and I am in no way insinuating that clomid is superior. Nelson completely misrepresented the study (HIV status, Duration of treatment) and I just wanted to set the record straight.

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GRANTED, I SKIMMED SOME DETAILS AND THAT'S MY ERROR, BUT THE CONCLUSION IS THE SAME. THE TESTS WERE FLAWED FOR THE REASONS MENTIONED. YOU DON'T SEEM TO WANT TO ACKNOWLEDGE THAT.


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Let me ask you this. Why do you think there is such a difference in the experiences of users on this message board, vs those who take clomid in a clinical setting. Remember a drug company is banking 100's of millions of dollars on the idea that clomid can both effectively raise test with minimal negative sides.

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YOU JUST ANSWERED YOUR OWN QUESTION. THIS IS A DRUG THAT ISN'T EVEN DESIGNED FOR THIS PURPOSE BUT IF THEY CAN SELL IT AS SUCH, THEY'LL FIND A STUDY THAT SAYS RHOADE ISLAND IS BIGGER THAN ALASKA TO PROVE IT. THERE IS ZERO INVESTMENT IN CLOMID FOR THE PURPOSE OF RESTORING HPTA AND THIS STUDY IS HARDLY A BIG EXPENSE.



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I would not be so quick to discount it, when TAKEN at the proper DOSAGE.

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THERE IS NONE. ODDLY ENOUGH, AT A LOW DOSAGE CLOMID CAN WORK WORSE, SINCE IT'LL ADD ESTROGEN BUT NOT ENOUGH TO COMPETE FOR RECEPTOR ACCEPTANCE. THE POINT IS, THERE ARE BETTER WAYS. AND CLOMID IS SOMETHING THAT IS VERY MISUNDERSTOOD. IF YOU WANT TO GO WITH THE ACCEPTED THINKING YOU SHOULDN'T USE STEROIDS BECAUSE PEOPLE IN THE THE MEDICAL PROFESSION SAY THEY'LL KILL YOU.

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sugashane said:
Damn. So do you think people should have several different oprions for their first few cycles so they know how each affects them? Or just run one so you know exactly how that one will affect you?
People always want to take the cheap way out. They do it with there cycles,there pct and even there diets.

Pct is not the time to be cheap. Its the most importent part of the cycle. After all it matters nothing what you gained if you can't keep it and stay in the gym after it.

Yes I think people should have options on hand. They should have everything covered.
 
For someone that has been in the game for so long I feel you are totally ignoring the positive evidence. I have never said the original study post at the beginning of this thread was the end all be all. In 2003 Columbia University published an article summarizing their study on the use of Clomid at 25mg/day to increase test levels. Pasted below is the pertinent information.

The Columbia study evaluated the use of clomiphene citrate tablets in 36 Caucasian men with hypogonadism, which was defined as a serum testosterone level < 300 ng/dl. Each patient received a daily dose of 25 mg of clomiphene citrate. The average patient age was 39 years, with 12 over age 40. The average pretreatment testosterone level was 247.6 ng/dl. All patients received the drug for at least three months; the entire group was followed for 1 year.

By the first follow-up visit, which occurred between four and six weeks of the start of therapy, the average testosterone level rose to 610 ng/dl, an increase of 146 percent compared with baseline. This response was seen in all patients regardless of age.
No patients reported any of the known side effects of clomiphene citrate, such as hot flashes, visual disturbances, or headaches. “In fact, most patients reported improvements in overall well-being, sex drive, physical strength, and mood on follow-up visit interviews. Some experienced these changes in as little as three months of therapy,” points out Dr. Fisch.


Perhaps you can clarify why the findings by doctors at Columbia university directly conflict with your claim that a dose of 25mg/day will actually make the situation worse.


YOU JUST ANSWERED YOUR OWN QUESTION. THIS IS A DRUG THAT ISN'T EVEN DESIGNED FOR THIS PURPOSE BUT IF THEY CAN SELL IT AS SUCH, THEY'LL FIND A STUDY THAT SAYS RHOADE ISLAND IS BIGGER THAN ALASKA TO PROVE IT. THERE IS ZERO INVESTMENT IN CLOMID FOR THE PURPOSE OF RESTORING HPTA AND THIS STUDY IS HARDLY A BIG EXPENSE.


Again you are incorrect. A drug cannot be sold unless it has received FDA approval. This means the drug company has to show that
A. The drug is effective at treating medical issue in question (raising test in this case)
B. The side effects inccured by the usage of the drug are minimal

The average cost to bring a drug through the FDA for approval is around a billion dollars. The trans isomer of clomid, (normal clomid is both cis and trans) is currently in phase III trials. If you read the preliminary data from the phase I and II trials you will see that the response to this method has been overwhelmingly positive. So in reality there is an incredible amount of money invested in the idea that clomid can effectively restore test levels.
 
alphatest said:
For someone that has been in the game for so long I feel you are totally ignoring the positive evidence. I have never said the original study post at the beginning of this thread was the end all be all. In 2003 Columbia University published an article summarizing their study on the use of Clomid at 25mg/day to increase test levels. Pasted below is the pertinent information.

The Columbia study evaluated the use of clomiphene citrate tablets in 36 Caucasian men with hypogonadism, which was defined as a serum testosterone level < 300 ng/dl. Each patient received a daily dose of 25 mg of clomiphene citrate. The average patient age was 39 years, with 12 over age 40. The average pretreatment testosterone level was 247.6 ng/dl. All patients received the drug for at least three months; the entire group was followed for 1 year.

By the first follow-up visit, which occurred between four and six weeks of the start of therapy, the average testosterone level rose to 610 ng/dl, an increase of 146 percent compared with baseline. This response was seen in all patients regardless of age.
No patients reported any of the known side effects of clomiphene citrate, such as hot flashes, visual disturbances, or headaches. “In fact, most patients reported improvements in overall well-being, sex drive, physical strength, and mood on follow-up visit interviews. Some experienced these changes in as little as three months of therapy,” points out Dr. Fisch.


Perhaps you can clarify why the findings by doctors at Columbia university directly conflict with your claim that a dose of 25mg/day will actually make the situation worse.





Again you are incorrect. A drug cannot be sold unless it has received FDA approval. This means the drug company has to show that
A. The drug is effective at treating medical issue in question (raising test in this case)
B. The side effects inccured by the usage of the drug are minimal

The average cost to bring a drug through the FDA for approval is around a billion dollars. The trans isomer of clomid, (normal clomid is both cis and trans) is currently in phase III trials. If you read the preliminary data from the phase I and II trials you will see that the response to this method has been overwhelmingly positive. So in reality there is an incredible amount of money invested in the idea that clomid can effectively restore test levels.
And every med site and University across the world has also listed is shitty sides. They are 100% real and they happen more often then they don't.

So even if clomid works which I myself never said it didn'. It still sucks big balls in my book.
 
Again you are incorrect. A drug cannot be sold unless it has received FDA approval. This means the drug company has to show that
A. The drug is effective at treating medical issue in question (raising test in this case)
B. The side effects inccured by the usage of the drug are minimal

The average cost to bring a drug through the FDA for approval is around a billion dollars. The trans isomer of clomid, (normal clomid is both cis and trans) is currently in phase III trials. If you read the preliminary data from the phase I and II trials you will see that the response to this method has been overwhelmingly positive. So in reality there is an incredible amount of money invested in the idea that clomid can effectively restore test levels.[/QUOTE]









so what did the fda aprove the use of clomid for??????????????????
 
needtogetaas said:
And every med site and University across the world has also listed is shitty sides.

At 25mg/day? Every study I have read reports no sides in the test subjects. But if you post one up I'll quickly change my opinion.
 
so what did the fda aprove the use of clomid for??????????????????

The trans isomer of clomid is currently in phase III clinical trials for the treatment of hypogonadal men. If approved it could be used in the place of androgel/test injections to help raise test levels.
 
alphatest said:
The trans isomer of clomid is currently in phase III clinical trials for the treatment of hypogonadal men. If approved it could be used in the place of androgel/test injections to help raise test levels.
Lets keep in mind you tried to use that clomid was fda approved for pct in your argument. Thats you in blue.

Just because its in a faze or what ever dos not make it ok to out right say thats what its been approved for. Seems small to you, but its not to me. It was approved for women right now. Let us not forget this. It may never be approved for anything else. Lets not jump the gun my little buddy.


Again you are incorrect. A drug cannot be sold unless it has received FDA approval. This means the drug company has to show that
A. The drug is effective at treating medical issue in question (raising test in this case)
B. The side effects inccured by the usage of the drug are minimal
 
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