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lostinfitness
New member
bad times bro, hopefully he will be ok. the problem lies in the fact that there are not facilities like public hospitals that are mandated to provide care to dental patients.
Friend in critical care
- Thread starter makaveli25
- Start date
Big_Joe
New member
If he had an infection, read abscess, in his tooth that was bad enough to cause puss to drip into his mouth then his whole body is infected. He probably does have Rhabdomyolysis but it's from systemic infection. It wasn't that long ago that if you got an abscess in your tooth you would probably die if it didn't get pulled right away. I know it's a hard ass thing to say but he if doesn't change his life he's dead. And I mean a complete and total change. Something like finding Jesus and entering a monastery or becoming a pastor.
lostinfitness
New member
no foreign substances need enter his body.
Rhabdomyolysis can be a serious thing. No need for Dr. House. Muscle soreness + tea colored or black urine = rhabdo until proven otherwise.
Hopefully that have checked his liver enzymes and billirubon count, etc. I would think it is surely a liver issue...
There are a few reasons for black urine –
found this link, hope it helps...Good luck bro', if your buddy is not getting anywhere, make sure he gets a few opinions, dont just take a rehab doctors opinion...go to a hard core specialist.
1) A build-up of haemoglobin ( Hb for short ) products in the urine
2) Colourings such as food dyes or drugs in the urine.
Haemoglobin products have 2 sources - in the first the components of Hb
are not put together properly because of an enzyme deficiency, this
condition is called porphyria and it is a genetic disease. There are 8
enzymes in the chemical pathway that builds Hb and so there are 8
different kinds of porphyria. There are a wide range of clinical symptoms
associated with porphyria one of which is dark coloured urine. Other
symptoms include mental illness if the Hb products collect in the brain
and interfere with normal brain activity - a famous sufferer of this
condition was King George III who ruled England in the late 1700s and
early 1800s. If the Hb products collect in the skin they can be broken
down in sunlight to form reactive chemicals which attack the skin and
leave the skin very sensitive to some chemicals such as the oils in
garlic - this condition is thought to be the source of some vampire
legends as the sufferers would avoid the sun and garlic. A good website
explaining some forms of porphyria can be found at http://www.uct.ac.za/depts/liver/porphpts.htm
If you get onto any web search engine and enter porphyria as the keyword
you will find a large selection of sites dealing with the subject, some
will be of a technical nature such as the one above and others will be
personal sites by sufferers sharing their experiences.
The other source of Hb products is the destruction of red blood cells
(RBCs for short) which is called haemolysis. Once the Hb is released from
the RBCs it starts to form breakdown products, one of which is bilirubin -
this causes the yellow discolouration of skin, eyes, plasma and urine in
jaundice. The more breakdown products present in the urine the darker the
discolouration from bright yellow through orange to dark brown / black. If
the kidneys are damaged by the disease process causing the haemolysis or
if there is surgery affecting the kidneys, bladder or connected organs
then intact RBCs can pass into the urine adding to the discolouration of
the urine.
There are many causes of haemolysis -
Bacterial infections such as meningitis may release toxins that destroy
RBCs.
Viral infections such as dengue fever or yellow fever.
Parasite infections such as Plasmodium falciparum ( a species of malaria )
causes black water fever.
Information on these diseases can be found at http://www.astdhpphe.org/
Mechanical damage to RBCs caused by long periods of marching or running
called 'march haematuria' or prolonged bare hand playing of bongo drums.
RBC antibodies may attack RBCs in circumstances such as an incompatible
transfusion. A person is transfused with RBCs that carry a cell marker (
antigen ) that the immune system recognises as foreign to that person and
so the immune response destroys the transfused RBCs.
Some drugs cause haemolysis by causing a build up of toxic by-products
that the body cannot remove because of an enzyme deficiency such as
Glucose -6- Phosphate Dehydrogenase deficiency during treatment with
Quinine - an antimalarial drug.
Genetic disorders such as sickle cell anaemia and thalassaemia cause
haemolysis.
There are many other causes of haemolysis and a search of the internet
using the keywords of haemolysis +drugs / antibodies / infections etc
should yield a lot of information, but remember to use a second keyword as
searching for haemolysis alone will turn up several thousand sites.
As for the second cause of urine discolouration - food dyes etc, these are
usually harmless reactions which go once the source of the dye is removed
from the diet.
A website covering all kinds of causes of urine discolouration can be
found at Urine - abnormal color
Hope this helps.
There are a few reasons for black urine –
found this link, hope it helps...Good luck bro', if your buddy is not getting anywhere, make sure he gets a few opinions, dont just take a rehab doctors opinion...go to a hard core specialist.
1) A build-up of haemoglobin ( Hb for short ) products in the urine
2) Colourings such as food dyes or drugs in the urine.
Haemoglobin products have 2 sources - in the first the components of Hb
are not put together properly because of an enzyme deficiency, this
condition is called porphyria and it is a genetic disease. There are 8
enzymes in the chemical pathway that builds Hb and so there are 8
different kinds of porphyria. There are a wide range of clinical symptoms
associated with porphyria one of which is dark coloured urine. Other
symptoms include mental illness if the Hb products collect in the brain
and interfere with normal brain activity - a famous sufferer of this
condition was King George III who ruled England in the late 1700s and
early 1800s. If the Hb products collect in the skin they can be broken
down in sunlight to form reactive chemicals which attack the skin and
leave the skin very sensitive to some chemicals such as the oils in
garlic - this condition is thought to be the source of some vampire
legends as the sufferers would avoid the sun and garlic. A good website
explaining some forms of porphyria can be found at http://www.uct.ac.za/depts/liver/porphpts.htm
If you get onto any web search engine and enter porphyria as the keyword
you will find a large selection of sites dealing with the subject, some
will be of a technical nature such as the one above and others will be
personal sites by sufferers sharing their experiences.
The other source of Hb products is the destruction of red blood cells
(RBCs for short) which is called haemolysis. Once the Hb is released from
the RBCs it starts to form breakdown products, one of which is bilirubin -
this causes the yellow discolouration of skin, eyes, plasma and urine in
jaundice. The more breakdown products present in the urine the darker the
discolouration from bright yellow through orange to dark brown / black. If
the kidneys are damaged by the disease process causing the haemolysis or
if there is surgery affecting the kidneys, bladder or connected organs
then intact RBCs can pass into the urine adding to the discolouration of
the urine.
There are many causes of haemolysis -
Bacterial infections such as meningitis may release toxins that destroy
RBCs.
Viral infections such as dengue fever or yellow fever.
Parasite infections such as Plasmodium falciparum ( a species of malaria )
causes black water fever.
Information on these diseases can be found at http://www.astdhpphe.org/
Mechanical damage to RBCs caused by long periods of marching or running
called 'march haematuria' or prolonged bare hand playing of bongo drums.
RBC antibodies may attack RBCs in circumstances such as an incompatible
transfusion. A person is transfused with RBCs that carry a cell marker (
antigen ) that the immune system recognises as foreign to that person and
so the immune response destroys the transfused RBCs.
Some drugs cause haemolysis by causing a build up of toxic by-products
that the body cannot remove because of an enzyme deficiency such as
Glucose -6- Phosphate Dehydrogenase deficiency during treatment with
Quinine - an antimalarial drug.
Genetic disorders such as sickle cell anaemia and thalassaemia cause
haemolysis.
There are many other causes of haemolysis and a search of the internet
using the keywords of haemolysis +drugs / antibodies / infections etc
should yield a lot of information, but remember to use a second keyword as
searching for haemolysis alone will turn up several thousand sites.
As for the second cause of urine discolouration - food dyes etc, these are
usually harmless reactions which go once the source of the dye is removed
from the diet.
A website covering all kinds of causes of urine discolouration can be
found at Urine - abnormal color
Hope this helps.
Ugh, you're hearing hoofbeats and thinking zebras, not horses.
Degradation of hemoglobin causes bilirubinuria (bilirubin in the urine), which usually causes a dark orange/yellow color.
Rhabdomyolysis is the breakdown of muscle tissue, which releases myoglobin in the urine. This damages the kidney cells (by clogging the tubules) and causes acute renal failure. The urine is characteristically described as tea or coffee colored. A dipstick urinalysis will show strongly positive blood (because of reaction to myoglobin) but no RBC's on a microscopy exam.
The problem doesn't seem to be your friend's liver. It appears that it's a simple case of rhabdo with unfortunate consequences.
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