Hell yes. I'm really sensitive to most anti-e's. I get bitchy, cranky and lose my sex drive with 1 tab of Arimidex, Nolvadex, etc. Now, I take 1 drop (yes, onlly 1 drop) of AG-Guys aromasin every night, or every other night on cycle. Anything more than that and I would be a complete train wreck. No gynecomastia, estro or mood issues at this dose.