Diagnosed with Nephrotic Syndrome (Kidney infection)

[ap282]

Okay so i noticed massive bloating about 1.5 months ago and went to the doctor after a couple of weeks i ended up getting my bloodwork done and my cholesterol came back at 500, my triglycirides came back at 550, I did a 24 hour urine sample and it came back with me urinating 10 grams of the protien Albumin, the normal amount that is to be secreted is 150mg/day. This protien helps keep fluids inside your body, without it or if you are diffecient then fluid tends to leak out into your soft tissues as it did to me. My BP was also up at around 150/80. The doctor told me that all of these things are causing my damage to the glomeri in my kidneys, that is the filter that usually holds back the protien albumin. The doctor prescribed me an ACE inhibitor for my blood pressure and to reduce the protien coming out of my urine. He prescribed me a corticosteroid to help bring down the inflamation, and suppress my immune system response to the infection, he also gave me some cholestrol medicine, and a medication to help bring down my tryglycerides. I have been on that medication for about 2 weeks. He also prescribed me a strong dieuretic with a potassium pill 2 days ago and i lost 10lbs of water in that time, i was way bloated from the low albumin. The doctor also told me that my white blood cell count is double what it should be and that its possible that the white blood cells are attacking my kidneys and putting them under stress. The doctor has seen this before and doesnt think its a huge cause for alarm, but he does want me to see a nephrologist as soon as possible, because he is worried that this can lead become worse and thinks the nephrologist can attack the problem with more potent medication.

I want to know if anyone has ever experienced this before and what the length of recovery was, or if anyone knows anyone with this condition. I had stopped my cycle back when i noticed the bloating about 1 month ago. The doctor thinks i will bounce back because i am only 23 but i have concerns about future kidney problems. I guess the toxicity of the steroids cause this to happen according to the doctor. Maybe a bad batch, i have taken AAS before with absolutly no problems. Anyway just want to hear what you guys have to say if your familiar with this problem. Thanks and god bless

I was on
600mgs EQ/ week
75mgs Tren Ace/EOD
100mgs Test Prop/EOD
I was on this cycle for 5 weeks when i noticed the problem of swelling. I continued 2 more weeks and then cut the cycle.

 

[KUSSEIN]

Sorry to hear about that bro!

 

[bigrand]

Doubt it was the AAS
Have you had a strep infection lately?

In cases of acute glomerular nephritis, antigen-antibody complexes get logged in the glomerulus and WBC release enzymes that breakdown the complex, but also damage the glom so it cant filter properly.
Its baiscally an auto immune disorder.
Only reason i ask is the very high level of WBCs seen in your case, in cases of Nephrotic syndrome, patients have decreased immune system competence.

All other symptoms are consistant with NS.


And yes, it can be serious serious (if underlying disease leads to renal failure), but in many cases you have spontaneous recovery. There are several causes for NS, you need to see the nephrologist to determine the course of action, typically corticos or cyclophosphamide (only if chronic relapses) are used and corticos work well. Diuretics are used sparingly and edema is usually treated conservativly.

 

[GOLUAN]

hope u feel better bro!

 

[ap282]

Doubt it was the AAS
Have you had a strep infection lately?

In cases of acute glomerular nephritis, antigen-antibody complexes get logged in the glomerulus and WBC release enzymes that breakdown the complex, but also damage the glom so it cant filter properly.
Its baiscally an auto immune disorder.
Only reason i ask is the very high level of WBCs seen in your case, in cases of Nephrotic syndrome, patients have decreased immune system competence.

All other symptoms are consistant with NS.


And yes, it can be serious serious (if underlying disease leads to renal failure), but in many cases you have spontaneous recovery. There are several causes for NS, you need to see the nephrologist to determine the course of action, typically corticos or cyclophosphamide (only if chronic relapses) are used and corticos work well. Diuretics are used sparingly and edema is usually treated conservativly.

Naw i have not had any sickness at all. I actually feel real good right now. Since the diuretics kicked in i feel normal again besides the fact that my calfs muscles dissapeared. That actually makes sence about the enzymes coming from the white blood cells that get logged into the glomeri the doctor told me that it is what is causing my inflammation and the damage to the kidney its basically over reacting to the infection. I went in for another blood test on Friday i will get the results back this Monday 7-17-06, if my levels have not fallen as far as cholesterol, tri's, or anything else since i have been on this medication for the past 2 weeks then i will have to see a nephrologist, asap.

The reason i thought it was the AAS is because i have never been sick to my kidneys before and high levels of cholesterol and tri's and infection all happend when i was on my cycle. I am pretty sure that the AAS triggered the high tri's and cholesterol and high BP, that in return put my kidneys under a whole lot of stress, and caused an infection from the toxicity of the AAS.

 

[LiquidPhire]

OMFG They hurt like a bitch, I had a kidney infection and ended up in the ER for a day, fucken pissed some blood out and it hurt like a mother fucken bitch.. good luck it will pass

 

[Triple J]

Your body will raise its blood lipid levels in an innate effort to try to make up for the lost albumin. The kidneys will release renin, which activates ACE, leading to a rise in aldosterone, to raise blood pressure. This is selfish effort by the kidneys to increase glomerular filtration rate. But since the glomerularis are rendered dysfunctional by the attack it doesn't do any good. The most frequent cause of acute glomerular nephritis is strep, which results in an allergic response to the antibody complex in the glomeularis. However other things are also known to trigger this sensitivity response besides strep, and it can also be idiopathic (unknown cause). Which seems to be the case here. If there was no other illness or infecton I would probably be thinking about the tren or something about the quality of the gear, too I suppose.

 

[macrophage69alpha]

trenbolone has been linked with kidney issues, though this has not been established and it still highly debated.

it is probably more likely that trenbolone exacerbates underlying kidney issues in some individuals, likely because of its progestenic binding and activity profile. though that is again, debatable

 

[bigrand]

Your body will raise its blood lipid levels in an innate effort to try to make up for the lost albumin. The kidneys will release renin, which activates ACE, leading to a rise in aldosterone, to raise blood pressure. This is selfish effort by the kidneys to increase glomerular filtration rate. But since the glomerularis are rendered dysfunctional by the attack it doesn't do any good. The most frequent cause of acute glomerular nephritis is strep, which results in an allergic response to the antibody complex in the glomeularis. However other things are also known to trigger this sensitivity response besides strep, and it can also be idiopathic (unknown cause). Which seems to be the case here. If there was no other illness or infecton I would probably be thinking about the tren or something about the quality of the gear, too I suppose.

His WBC count is why i though hemolytic strep infection, but he didnt have any S/S indicating such an prior infection.
COULD be something in the gear, doubt it though.......NS happens for several reasons, your nephrologist should be able to sort it out once he runs the proper tests.