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Dermacrine Info thread

  • Thread starter Thread starter Anthony Roberts
  • Start date Start date
Primordial Performance said:
Here is a saliva test we did on a 23 yr old subject. He was not using steroids, and started the Dermacrine with a high-normal testosterone level. Still, the Dermacrine boosted his levels up about 80-90%. He was using 40 spray pump ED. We are following up on his post dermacrine levels now and will have results to post within a week.

IMO, its the metabolites of DHEA that really mater. However, DHEA has been shown to up-regulate StAR protein, and therefore enhance the conversion of cholesterol > pregnenolone. This is considered one of the "rate limiting" steps in hormone production... and of course testosterone production.

The primary beneficial metabolites of DHEA are explained here -
http://www.primordialperformance.com/hormone_tree.cfm

-Pp

Have you included any women in your tests and what would be the dosage for a 23 yo female?
 
We don’t recommend Dermacrine for women due to the increase in testosterone that is causes. This could cause facial hair growth, and in the worst case may cause deepening of the voice and clitoral growth. (not necessarily bad I suppose)

However, if these side effects are of no concern for you then Dermacrine would be an excellent performance/strength boosting supplement, eliciting an even more pronounced effect due to women’s more pronounced response to male androgens. (androstenedione, testosterone, ect) Dermacrine would practically be steroids for women.

-Pp
 
Primordial Performance said:
We don’t recommend Dermacrine for women due to the increase in testosterone that is causes. This could cause facial hair growth, and in the worst case may cause deepening of the voice and clitoral growth. (not necessarily bad I suppose)

However, if these side effects are of no concern for you then Dermacrine would be an excellent performance/strength boosting supplement, eliciting an even more pronounced effect due to women’s more pronounced response to male androgens. (androstenedione, testosterone, ect) Dermacrine would practically be steroids for women.

-Pp
so Dermacrine=great for bb women who use aas any way.or maby even a better chose as the sides would be a bit less then aas. :)
 
Primordial Performance said:
We don’t recommend Dermacrine for women due to the increase in testosterone that is causes. This could cause facial hair growth, and in the worst case may cause deepening of the voice and clitoral growth. (not necessarily bad I suppose)

However, if these side effects are of no concern for you then Dermacrine would be an excellent performance/strength boosting supplement, eliciting an even more pronounced effect due to women’s more pronounced response to male androgens. (androstenedione, testosterone, ect) Dermacrine would practically be steroids for women.

-Pp

Thanks for the reply. I asked about the dosing because I assumed you wouldnt endorse women using as many sprays as a man. I think I'm gonna give this a try and just use half as many sprays as reccomended for men and see how it goes.
 
RottenWillow said:
Thanks for the reply. I asked about the dosing because I assumed you wouldnt endorse women using as many sprays as a man. I think I'm gonna give this a try and just use half as many sprays as reccomended for men and see how it goes.
cool.....love to here how it gos...yes using 3 pumps or around 20 spray would seem better for you....men use 4-5 pumps or 35-40 spray.
 
needtogetas said:
cool.....love to here how it gos...yes using 3 pumps or around 20 spray would seem better for you....men use 4-5 pumps or 35-40 spray.

yup ^^^
 
Gosh , I don't see how I can stop this stuff...
I had an awesome day in the gym despite not having such a great work week

I would like to say last week I had troubles with my wireless connections so I did not see previous comments I made about this product on this thread. Now that my connection is fine and I see my comments I still feel as if an "official" dermacrine thread is needed that is created by an unbiased third party. Having a dermacrine thread started by someone who sells a competitive product and who is also a COTB and can delete others posts is simply not a good way of going about this

So a new thread really needs to be created IMHO
 
gjohnson5 said:
Gosh , I don't see how I can stop this stuff...
I had an awesome day in the gym despite not having such a great work week

I would like to say last week I had troubles with my wireless connections so I did not see previous comments I made about this product on this thread. Now that my connection is fine and I see my comments I still feel as if an "official" dermacrine thread is needed that is created by an unbiased third party. Having a dermacrine thread started by someone who sells a competitive product and who is also a COTB and can delete others posts is simply not a good way of going about this

So a new thread really needs to be created IMHO
ya some one should get on that.lol
 
so if i understand all of this it goes

6-8wks dermacrine for pct
10-?wks hgc/clomid and dermacrine afterwards

but use aifm while on because it presents better than dermacrine while on?
some of you guys speak like rocket scientist.lol
 
23CALIBRO said:
so if i understand all of this it goes

6-8wks dermacrine for pct
10-?wks hgc/clomid and dermacrine afterwards

but use aifm while on because it presents better than dermacrine while on?
some of you guys speak like rocket scientist.lol
:)
 
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RottenWillow said:
Thanks for the reply. I asked about the dosing because I assumed you wouldnt endorse women using as many sprays as a man. I think I'm gonna give this a try and just use half as many sprays as reccomended for men and see how it goes.

Yea, keep us posted please... Would be very interesting to see how it effects a female!
 
23CALIBRO said:
so if i understand all of this it goes

6-8wks dermacrine for pct
10-?wks hgc/clomid and dermacrine afterwards

but use aifm while on because it presents better than dermacrine while on?
some of you guys speak like rocket scientist.lol


Bro,

Are you askin if Dermacrine would be the right choice for a longer 10 wk cycle?

If so, yes, Dermacrine would be fine for PCT, but we always recommend the use of HCG during the cycle to keep your balls from shrinking.

AIFM is only needed if you are running lots of Test or Dbol and need to reduce estrogen.

-Pp
 
needtogetas said:
so for women like willow who is going to be using it it will last twice as long because she is going to go with 20-30 bumps.

Yes, but I suggest she keep an eye on herself. She may only want to use the product for several weeks at a time to try and avoid any masculinizing side effects.

-Pp
 
Primordial Performance said:
Yes, but I suggest she keep an eye on herself. She may only want to use the product for several weeks at a time to try and avoid any masculinizing side effects.

-Pp
4 weeks on couple weeks off.then back on again.so a bottle could last here a long time. :)
 
gjohnson5 said:
Gosh , I don't see how I can stop this stuff...
I had an awesome day in the gym despite not having such a great work week

I would like to say last week I had troubles with my wireless connections so I did not see previous comments I made about this product on this thread. Now that my connection is fine and I see my comments I still feel as if an "official" dermacrine thread is needed that is created by an unbiased third party. Having a dermacrine thread started by someone who sells a competitive product and who is also a COTB and can delete others posts is simply not a good way of going about this

So a new thread really needs to be created IMHO
:)
 
This may have been asked, but for someone who isnt ON cycle or in PCT... which would be better, AIFM or Dermacrine. This would be aimed at all those natty lifters.
 
ProtienFiend said:
This may have been asked, but for someone who isnt ON cycle or in PCT... which would be better, AIFM or Dermacrine. This would be aimed at all those natty lifters.
deff derma bro......

THE MAIN BENEFITS

* Muscle - Dermacrine provides the anabolic foundation for increased strength and lean muscle mass though stimulation of testosterone, growth hormone, and IGF-1. The hormones in Dermacrine also have an anti-catabolic effect by antagonizing the catabolic effects of cortisol.

* Fat loss - Dermacrine includes naturally occurring hormones to increase thermogenesis in the liver while also supporting thyroid function. Dermacrine also lowers estrogen, thus inhibiting estrogen-related fat depositing.

* Sexual function - Dermacrine will help rejuvenate the primary male androgens while also creating a healthy testosterone/DHT/estrogen profile to maximize a man's libido and sexual performance.

* Immune support - Dermacrine increases several key hormones which positively modulate the immune system.

* Mental Performance & Stress control - Dermacrine contains neurosteroids that have been positively correlated to support memory and well-being and manage excessive stress


it raises your test up to 140%

Dermacrine is positively correlated to increase lean body mass and reduce fat mass through four main mechanisms: Combating cortisol dominance, increasing GH & IGF-1, increasing androgens, reducing estrogen, and increasing thermogenesis.

Cortisol dominance can be described as having an unbalanced hormonal profile favoring cortisol activity either by having high cortisol levels, low androgen levels, or both. This hormonal shift towards cortisol dominance can be caused by excessive physical or mental stress [↑cortisol], post steroid use [↓androgen], alcohol consumption [↓androgen↑cortisol] and old age [↓androgen↑cortisol]1-4 In all cases, cortisol dominance is a condition associated with decreased muscle mass, increased fat mass, and degradation of general well being.4, 5, 17, 18, 19 Excessive cortisol activity can also decrease production of steroid hormones and androgens creating further cortisol dominance.6In order to neutralize the negative effects of cortisol and avoid cortisol dominance, one must maintain optimum levels of critical androgens.24 [Illustrated on the “Hormones” page]

DHEA is an immediate precursor to the critical androgens known as androstenediol and androstenetriol.20,21 These metabolites of DHEA are known to have powerful anti-catabolic and anti-cortisol activity by counteracting the muscle wasting and immuno-suppressive effects of cortisol.23,24 Both androstenediol and androstenetriol act as anabolic hormones and have been shown to enhance recovery and tissue repair from injury.24,25 Furthermore, DHEA, androstenediol and androstenetriol have been found to be potent enhancers of the immune system, by helping to fight off infection, protect against lethal radiation, and restore immunity during times of stress.26-29

Studies using DHEA with elderly subjects and HIV patients have also shown restoration of immune system activity by increasing the division of immune promoting cells.30-32 Its been proposed that this increased division of immunogenic cells is a result of DHEA increasing the bioavailability of IGF-1 and enhancing cellular mitosis.31

DHEA’s stimulation of IGF-1 activity is supported by other human trials.33,34 These studies have also revealed that DHEA can stimulate GH release. Therefore, the increase in IGF-1 can be explained by the increase in GH, since GH is converted to IGF-1 in the liver. An explanation for the GH release can be explained here by Suarez et al. 2005,

“it can be inferred that DHEA may release GH in vivo by reducing somatotrope responsiveness to somatostatin, as well as by enhancing somatotrope sensitivity to GHRH.”

In general terms, DHEA sensitizes the pituitary to GHRH and boosts the release of GH.34

The increase in GH and IGF-1 with DHEA supplementation has shown to have real world benefits in muscle growth, fat loss and muscle strength in various human studies.35-37 Besides having a direct effect on body composition, IGF-1 plays an important role in steroidogenic hormone production. Most notably, IGF-1 stimulates the conversion of cholesterol to pregnenolone, otherwise known as the rate limiting step in steroid hormone synthesis. Enhancement of steroidal synthesis by IGF-1 is accomplished by IGF-1’s action upon the leydig cell and stimulation of CYP11A, 3b HSD, and StAR. 38-40 Direct stimulation upon the leydig cell from IGF-1 helps initiate the first steps in creating anabolic hormones such as androstenedione, androstenediol, and t estosterone.

Concerning the process of steroidogenesis, it is known by most steroid users that anabolic androgenic steroids (AAS) inhibit natural testosterone production. However, most do not realize that AAS also inhibit DHEA production along with all other beneficial androgens.9-12 Most assume that simply using an “anti-estrogen” and inhibiting estrogen will prevent testicular shutdown and restore testosterone production, however this is not the case for the heavy steroid users. High levels of testosterone (AAS) can actually inhibit and degrade the enzymes responsible for its own creation, such as the 17a-hydroxylase enzyme.13 It can be theorized then, that all testosterone derivatives and AAS's such as stanozolol, methandrostenolone, nandrolone and even oxandrolone can directly inhibit the enzymes responsible for steroid production and cause long term suppression of steroidogenesis, aside from causing direct hypothalamus and pituitary suppression via the androgen receptor.

On the contrary, DHEA and pregnenolone appear to encourage there own production by stimulating the enzymes and hypothalamus to increase androgen production. Pregnenolone has been found to increase the release of gonadotropin releasing hormone (GnRH) from the pituitary, and thereby increase luteinizing hormone (LH) and follicle stimulating hormone (FSH) release.7 DHEA has been shown to stimulate StAR at a cellular level, therefore enhancing uptake of cholesterol into the mitochondria and up-regulating the rate limiting step in hormone synthesis.8 These properties of DHEA and pregnenolone seem to make them an excellent choice for post cycle therapy (PCT) or hypogonadal men, but there remains a problem.

Plain ol DHEA and pregnenolone are limited in there supplemental usefulness due to there eventual conversion to estrogen through interaction with the aromatase enzyme (CYP 19). Excessive estrogen can inhibit the hypothalamus pituitary testicular axis (HTPA), and increase fat deposits and water retention41. Fortunately, Dermacrine limits estrogen synthesis by including the Phyto Aromatase Inhibitor complex, consisting of three potent plant based aromatase inhibitors, namely 7,8 benzoflavone, chrysin and resveratrol.42,43 These flavonoids directly compete with aromatizing androgens for interaction with the aromatase enzyme as well and inhibit the production of the aromatase enzyme itself.44,45 As a result, estrogen is kept down, and the steroidogenic enzymes are kept up, therefore making Dermcrine one powerful hormone rejuvenator.

As another benefit to controlling estrogen levels, fat burning is made much easier. The fat loss is further catalyzed by the ingredients DHEA and 7-keto DHEA. Both of these thermogenic hormones increase calorie burning and fat loss by directly activating the mitochondrial and cytosolic thermogenic enzymes in liver.46,47.

Numerous studies with animals and humans have shown dramatic increases in fat and weight loss with the use of DHEA and 7-keto DHEA.48-51 Since DHEA is not a stimulant, the fat loss is accomplished without the jitters, anxiety or heart palpitations associated with drugs like caffeine and ephedra.

In summery, Dermacrine may help improve body composition by antagonizing cortisol, stimulating GH & IGF-1 release, raising anabolic/androgenic hormones, reducing estrogens and eliciting a thermogenic response from liver enzymes.


Dermacrine is positively correlated to support libido, erectile function and fertility through three main mechanisms: Increasing androgens, reducing estrogens and promoting healthy blood flow.

As its been discussed before, low levels of DHEA can be caused by steroid use, alcohol abuse, poor diet, lack of sleep, old age and excessive physical or mental stress. Its well established that low levels of DHEA (and testosterone) is associated with reduced sexual interest and ability.60,61 Therefore, it can be inferred that supplementing with DHEA can help support sexual function. Other androgens such as androstenedione, testosterone and their 5a-reduced metabolites; androstanedione, dihydrotestosterone, and androsterone share a strong influence on sexual function. All of these androgens have important neurobiological effects and act directly on the central nervous system to initiate sexual interest and stimulus.52 Dermacrine can incre ase these critical androgens by providing the main precursor, DHEA.

Another mechanism by which Dermacrine increases androgen production is by reducing estrogens and preventing negative feedback upon the hypothalamus pituitary testicular axis (HPTA). Our proprietary Phyto Aromatase Inhibitor complex (Phyto AI) effectively inhibits the aromatase enzyme (CYP 19) and reduces estrogen.42-45 In fact, chrysin, 7,8 benzoflavone, and resveratrol have been successfully used in animal studies to increase sperm count and fertility by inhibiting estrogen, and increasing testosterone.53,54 These animal studies also noted an “aphrodisiac” like property from these flavones, which makes sense since chrysin and 7,8 benzoflavone are the main active constituents from passion flower (passiflora incarnate) which has long been known to posses aphrodisiac like properties and has been prescribed for sexual disorders in other countries.15,16

Most importantly, the above animal studies also noted increases in both LH & FSH. As you may be aware, LH is a hormone sent from the pituitary which stimulates the testis to produce androgens, such as testosterone. Less known by most, is the importance of FSH. Without adequate FSH, LH would quickly desensitize the testis and androgen production would come to a halt, since FSH sensitizes the testis to the effects of LH by increasing the number of LH receptors in the testis. Many steroid users and/or hypogonadal men will attempt to restore their testosterone production by administering hCG (LH mimicker). However, HCG can quickly desensitize the testis and lead to further suppression of testosterone production. A better protocol would be to administer hCG with FSH (if one could obtain it), or simply buy our product.

As a final benefit, the ingredients in Phyto AI have shown to be “vasorelaxants”, which may help promote blood flow to genitalia and support erectile function.55-57

Note: Several steroidal aromatase inhibitors such as formestane (4-OHA), 1,4,6-androstatriene-3,17-dione (ATD) and androstenetrione (6-OXO) can directly inhibit the HPTA by interacting with the androgen receptor leading to a sequential reduction in LH.58,59 We DO NOT recommend the use of these steroidal based aromatase inhibitors’s.


Dermacrine is positively correlated to support memory, well being, and cognitive function by providing the neursteroids DHEA and pregnenolone.

As pregnenolone and DHEA enter circulation they pass through the liver and become sulfated.62 Once sulfated, these hormones become neurosteroids and interact with the brains neurotransmitters to influence excitability, sleep quality, memory, concentration and other physiological functions.63,64 In fact, these neurosteroids are so important, low levels are associated with depression,74,75 insomnia69 and Alzheimer’s disease73. DHEA supplementation in humans has been successful in helping with sleep quality, well being and reducing depressive symptoms69-71,14, while DHEA and pregnenolone supplementation in animals have been successful in enhancing memory, mental performance, and stress control.63-65, 72 Whether or not higher than normal levels of DHEA or pregnenolone in humans enhances memory or functions as a “smart drug”, remains to be seen.
 
ProtienFiend said:
This may have been asked, but for someone who isnt ON cycle or in PCT... which would be better, AIFM or Dermacrine. This would be aimed at all those natty lifters.

Yes, derma has the perfect AI’s for someone not on cycle.

Hipsacjack,

You certainly can, but may I ask what the finesteride is for? It has got to be one of my least favorite drugs…. erectile problems, no libido, gyno, semi-depression, infertility, ect.

-Pp
 
Hipsacjack,

You certainly can, but may I ask what the finesteride is for? It has got to be one of my least favorite drugs…. erectile problems, no libido, gyno, semi-depression, infertility, ect.

-Pp[/QUOTE]

I started taking Finasteride about eight years ago for hair loss (age 21). It doesn't seem to be giving me any problems. If I stop taking it, my hair will slowly start to thin, and that's without AS. Starting about six months ago, I got a case of prostatitis and my doc said it's cool to keep with the 1.25mg Proscar along with prostate vitamins.
I'm was going to start a Test/Dbol with Aromasin and then Dermacrine PCT. What do you think?
 
hipsacjack said:
Hipsacjack,

You certainly can, but may I ask what the finesteride is for? It has got to be one of my least favorite drugs…. erectile problems, no libido, gyno, semi-depression, infertility, ect.

-Pp

I started taking Finasteride about eight years ago for hair loss (age 21). It doesn't seem to be giving me any problems. If I stop taking it, my hair will slowly start to thin, and that's without AS. Starting about six months ago, I got a case of prostatitis and my doc said it's cool to keep with the 1.25mg Proscar along with prostate vitamins.
I'm was going to start a Test/Dbol with Aromasin and then Dermacrine PCT. What do you think?[/QUOTE]


Sounds good to me.

From what I understand, you may be DHT deficient, and that can be the cause of your prostatiitis. So either you keep a full head of hair, with a iritated prostate, or visa vera.

-Pp
 
gjohnson5 said:
Gosh , I don't see how I can stop this stuff...
I had an awesome day in the gym despite not having such a great work week

I would like to say last week I had troubles with my wireless connections so I did not see previous comments I made about this product on this thread. Now that my connection is fine and I see my comments I still feel as if an "official" dermacrine thread is needed that is created by an unbiased third party. Having a dermacrine thread started by someone who sells a competitive product and who is also a COTB and can delete others posts is simply not a good way of going about this

So a new thread really needs to be created IMHO
this is the only problem derma has lol not that its a bad problem at all but most people love derma so much they want to stay on it for ever..dont forget you have to cycle derma 4 weeks on with some time off....derma is great for pct raising test helping with sex drive it dos every thing it says it dos and because it delivers what is says it dos people want to just keep taking it.

this derma was intended to be used for 4 weeks as a pct to bring back your test or just to bring your up your test levels even after use your test levels are higher but it was not intended for long term use.
 
needtogetas said:
this is the only problem derma has lol not that its a bad problem at all but most people love derma so much they want to stay on it for ever..dont forget you have to cycle derma 4 weeks on with some time off....derma is great for pct raising test helping with sex drive it dos every thing it says it dos and because it delivers what is says it dos people want to just keep taking it.

this derma was intended to be used for 4 weeks as a pct to bring back your test or just to bring your up your test levels even after use your test levels are higher but it was not intended for long term use.

That actually answers my question that I was getting ready to post.... So you are saying what.. 2 - 4 weeks off after use? This Friday will be my third full week and I'm loving it. So I just wanted to know how long to stay off of this before I begin back up..??? Thanks!!!!
 
Nice breakdown Needtogetgas.... If this was my first time on the threads... I would be at the site right now placing an order based on the breakdown that you gave for Dermacrine's effects.... I don't see why you would buy something else for PCT after that explanation.
 
ricanx99 said:
That actually answers my question that I was getting ready to post.... So you are saying what.. 2 - 4 weeks off after use? This Friday will be my third full week and I'm loving it. So I just wanted to know how long to stay off of this before I begin back up..??? Thanks!!!!


Yep, Dermacrine will raise test above normal-high levels, and this elevated test can eventually have an inhibitory effect of its own, so we recommend taking 3-4 weeks off between each 4 week use of dermacrine.

The body likes to stay in hormonal limbo, with daily spikes in testosterone. Its is best to occasionally allow the body to do this in order to avoid any suppressive effects…



-Pp
 
ricanx99 said:
Nice breakdown Needtogetgas.... If this was my first time on the threads... I would be at the site right now placing an order based on the breakdown that you gave for Dermacrine's effects.... I don't see why you would buy something else for PCT after that explanation.
:)
 
Primordial Performance said:
Yep, Dermacrine will raise test above normal-high levels, and this elevated test can eventually have an inhibitory effect of its own, so we recommend taking 3-4 weeks off between each 4 week use of dermacrine.

The body likes to stay in hormonal limbo, with daily spikes in testosterone. Its is best to occasionally allow the body to do this in order to avoid any suppressive effects…



-Pp

Thanks bro man! You guys are awesome. Thanks for all of the info and help!
 
Primordial Performance said:
Yep, Dermacrine will raise test above normal-high levels, and this elevated test can eventually have an inhibitory effect of its own, so we recommend taking 3-4 weeks off between each 4 week use of dermacrine.

The body likes to stay in hormonal limbo, with daily spikes in testosterone. Its is best to occasionally allow the body to do this in order to avoid any suppressive effects…



-Pp

What do you feel is the better time periods to avoid and suppressive effects, 2 weeks on 2 weeks off, or 4 weeks on 4 weeks off, or are they very similar?
 
Primordial Performance said:
To all home-brewers, here is a link to info on the empty topical solution -

http://www.elitefitness.com/forum/showthread.php?t=532587

-Pp

I received my order today and even though it said to use in the morning I had to start right away.

I will keep everyone posted as to my results and I will call it as i see it no BS'ing.

I am really excited about this products potential.

I'll be 47 this year and think this might be the ideal product for someone my age. Espeically since my GF is only 35!

Oh and I forget to ask two important questions.

1.) Why does it say avoid contact with genitals? Irritant issues or effects on the testis?

2.) You talk about transfer; if I put it on and 3 or 4 hours later my girl friend and I have hot, steamy, sweaty, Olympic style sex will it transfer on to her???
 
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How many days have you been on Dermacrine?

How long after you started did you start noticing all the great side effects??

gjohnson5 said:
Gosh , I don't see how I can stop this stuff...
I had an awesome day in the gym despite not having such a great work week

I would like to say last week I had troubles with my wireless connections so I did not see previous comments I made about this product on this thread. Now that my connection is fine and I see my comments I still feel as if an "official" dermacrine thread is needed that is created by an unbiased third party. Having a dermacrine thread started by someone who sells a competitive product and who is also a COTB and can delete others posts is simply not a good way of going about this

So a new thread really needs to be created IMHO
 
BigRupe said:
I received my order today and even though it said to use in the morning I had to start right away.

I will keep everyone posted as to my results and I will call it as i see it no BS'ing.

I am really excited about this products potential.

I'll be 47 this year and think this might be the ideal product for someone my age. Espeically since my GF is only 35!

Oh and I forget to ask two important questions.

1.) Why does it say avoid contact with genitals? Irritant issues or effects on the testis?

2.) You talk about transfer; if I put it on and 3 or 4 hours later my girl friend and I have hot, steamy, sweaty, Olympic style sex will it transfer on to her???

bump for some answers...
 
BigRupe said:
I received my order today and even though it said to use in the morning I had to start right away.

I will keep everyone posted as to my results and I will call it as i see it no BS'ing.

I am really excited about this products potential.

I'll be 47 this year and think this might be the ideal product for someone my age. Espeically since my GF is only 35!

Oh and I forget to ask two important questions.

1.) Why does it say avoid contact with genitals? Irritant issues or effects on the testis?

2.) You talk about transfer; if I put it on and 3 or 4 hours later my girl friend and I have hot, steamy, sweaty, Olympic style sex will it transfer on to her???
1.2 people that I know of on this board did in fact apply it directly to there balls and nothing happened to them.no pain and no sting or burning.I even sprayed it in my eyes on acsadent and nothing happend so I am pretty shore that is just a precautionary measure they put in place just to be safe........

2.transfer from you to your girl at that small of a dose will do nothing to her at all.they are more worried about you transferring it to small children bro....
 
needtogetas said:
1.2 people that I know of on this board did in fact apply it directly to there balls and nothing happened to them.no pain and no sting or burning.I even sprayed it in my eyes on acsadent and nothing happend so I am pretty shore that is just a precautionary measure they put in place just to be safe........

2.transfer from you to your girl at that small of a dose will do nothing to her at all.they are more worried about you transferring it to small children bro.....

Also, stay away from small canines such as daschunds, papillions, welsch corgis, and toy poodles.
 
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ZGzaZ said:
needtogetas said:
1.2 people that I know of on this board did in fact apply it directly to there balls and nothing happened to them.no pain and no sting or burning.I even sprayed it in my eyes on acsadent and nothing happend so I am pretty shore that is just a precautionary measure they put in place just to be safe........

2.transfer from you to your girl at that small of a dose will do nothing to her at all.they are more worried about you transferring it to small children bro....[/QUOTE]

Also, stay away from small canines such as daschunds, papillions, welsch corgis, and toy poodles.
ya
 
needtogetas said:
2.transfer from you to your girl at that small of a dose will do nothing to her at all.they are more worried about you transferring it to small children bro....


Damn and I was hoping it would make her want more sex. LOL
 
i have a 18 mos. old son. i'm thinking of running this for pct for upcoming cycle. how worried do i need to be about this transfer deal?? i mean, once it dries your good to go?? or you need to have no contact in the applied areas for how long??
 
gettinripped said:
i have a 18 mos. old son. i'm thinking of running this for pct for upcoming cycle. how worried do i need to be about this transfer deal?? i mean, once it dries your good to go?? or you need to have no contact in the applied areas for how long??
well look at it like this.if you rub it on your upper back,chest,shoulders then let it dry and put a shirt on.your kids not going to get any on him..... :)

I have 3 kids of my own bro 8,3,and 2 two boys and a girl.my kids clime all over me all day and a feel they are safe as long as I do it this way.if you go to the gym with it on just change your shirt when you get back.
 
What's the reasoning behind only administering it to your upper body and not your lower body and back also actually?
 
I am not a weight lifter..I am 39 years old and have just found out I have low Test. My doctor put me on Androderm. I have been on it for 6 weeks and my Test has not improved. I do drink a lot of soymilk and I have read this can put your body at a high Estrogen level. I think with this + Androderm has just shut down my Test even more.
I have thought of using E-Form while on Androderm to see if this would help? I have just discovered Dermcraine and wonder what would happen if I use it while on Androderm. My doctor says I may never be able to get off Androderm if my body won’t produce Test anymore so it will be like I am on a constant Test cycle. Any suggestions on how to keep estrogen down and help Androderm work. I have thought of a little Arimidex might help but I want To try to stay away from anything illegal for now.
 
dosteov said:
What's the reasoning behind only administering it to your upper body and not your lower body and back also actually?

Skin is the optimum site for delivery of the hormones and flavonoids contained in Dermacrine and is far superior to any oral pill or liquid.

Here's why:

Studies with un-methylated hormones such as DHEA and pregnenolone show poor oral bioavailability of about 3% compared to 30-40% when administered topically (3,4). Even if the oral dose is high, the digestive system still lacks the enzymatic activity to convert DHEA to its more active metabolites (e.g. 7alpha DHEA, 7keto DHEA, androstenediol, androstenetriol, androstenedione, testosterone, ect.) It is these metabolites that are responsible for the muscle building, immune stimulating, cortisol blocking, and fat burning effects of DHEA (5-8). In order for DHEA to convert to its active metabolites it must reach its "target organs" such as the adrenals and testis to interact with the appropriate enzymes. Fortunately, the skin contains a high concentration of these steroidogenic enzymes necessary for the conversion of DHEA to its active metabolites (9-15).

Aromatase inhibitors such as chrysin, 7,8 benzoflavone and resveratrol have been shown to have very poor oral bioavailability due to low intestinal absorption, extensive hepatic metabolism, and rapid elimination (1,2). This can explain the lack of "real world" results seen from oral chrysin supplements intended to reduce estrogen(16). Fortunately, these flavonoids have a very low molecular weight, allowing them to easily pass through the skin and reach the blood stream.


Enhancing the bioavailability of the active ingredients through our exclusive topical delivery system dramatically increases their physiological value and opens a new era for "dietary supplement" efficacy. We achieved this by designing the most cutting edge topical formula on the market; the OHV topical delivery system.




The skin can be described by three main layers: The epidermis (top layer), dermis and hypodermis (lower layer). The upper most layer of the epidermis is called the stratum corneum. The stratum corneum is a layer of dead compacted skin cells with a "waxy" texture which poses as the main barrier-to-entry for the skin. Therefore a dynamic transdermal carrier must be used for aggressive delivery of active ingredients. Our transdermal formula offers maximum delivery of active ingredients by utilizing the OHV system - Occlusion, Hydration, and Vasodilation.

* Occlusion - We create this occlusive layer with an invisible acrylic acid polymer. An occlusive barrier causes the skin temperature to slightly increase. This enhances the kinetic energy and "movement" of nutrients across the skin. Increased skin temperature can also help open sweat glands and hair follicles. Opened sweat glands and hair follicles give way to entry deep within the skin for delivery of the active ingredients.
* Hydration - High quality moisturizers and emollients are used to enhance skin hydration. Enhancing hydration helps "swell" and "soften" the skin for increased permeation of active ingredients. Penetration is further increased by including a light weight cosmetic oil derived from shark livers called squalane. Squalane oil mimics and merges with the skins natural sebum, and penetrates the skin incredibly well. This deep penetrating action of squalane carries the fat soluble active ingredients further into the skin.
* Vasodilation - Vasodilators are used to increase blood flow to the skin's surface by opening the local blood capillaries. The increased blood flow helps carry active ingredients away from the skin and into systemic circulation. Caution: Vasodilation is created by ingredients also known to increase photosensitivity, and may temporarily enhance the skins sensitivity to sunlight.

Our proprietary OHV blend safely optimizes delivery of the active ingredients through the skin. This is accomplished without any uncomfortable skin irritation, unpleasant odor, or residue. Rest assured that you are using the most scientifically advanced transdermal formula with the safest and highest quality ingredients.

For those interested in adding there own ingredients to our topical, we sell an "empty" OHV solution as stand alone product. See product page for more information.




Only apply the product to clean, dry skin. Apply product in the morning at least 8hr before bedtime to avoid insomnia. Wash hands after applying the product and avoid product contact with eyes, mouth and genitals.

Use Dermacrine everyday for 2-4 weeks. We recommend taking equal time off between each cycle. For example: Use product 4 weeks, take 4 weeks off, and then repeat.

If using the trigger sprayer - Spray 30-50 spray pumps in hand and apply to the illustrated application area. We recommend this pump during travel to avoid leakage.

If using the lotion pump - Pump 4-6 pumps in hand and apply to the illustrated application area. We recommend this pump for fastest application, however pump may leak during travel.

For best results: Shower and exfoliate skin with body-scrubber to remove dead skin cells. When applying product, spread across skin quickly to cover as much surface area as possible before product dries. Shaving the skin is recommended, but not required.

Remember: Dermacrine's topical formula contains ingredients that temporarily increase photosensitivity (3-4hr) and increase chance of sunburn. Therefore, caution is advised for those applying the product immediately before direct sun exposure.








the skin on the upper chest,shoulders and upper back are optimal because
Opened sweat glands and hair follicles give way to entry deep within the skin for delivery of the active ingredients.
were you sweat is were your skin is the most open.


also because these areas of the body are easy to cover up then say the forearms were putting it on areas like this will cause contact with others.
 
dosteov said:
What's the reasoning behind only administering it to your upper body and not your lower body and back also actually?

The upper shoulders and back have highest concentration of 3b HSD and 17b HSD. These are the enzymes required to convert the DHEA to testosterone and other androgens. The DHEA is actually converting to testosterone as it passes the skin and interacts with these enzymes…

The stomach is simply a good place to apply any TDS because of its thinner epidermis.

-Pp
 
Primordial Performance said:
The upper shoulders and back have highest concentration of 3b HSD and 17b HSD. These are the enzymes required to convert the DHEA to testosterone and other androgens. The DHEA is actually converting to testosterone as it passes the skin and interacts with these enzymes…

The stomach is simply a good place to apply any TDS because of its thinner epidermis.

-Pp
:)
 
artificialaspirations said:
which 3 hormones are weight lifters supposed to check?

It depends on what your interested in diagnosing, or learning more about.

Most guys test DHEA, testosterone and E1 (or E2)

FYI, If you think your under a lot of stress and want to see if you cortisol is high, then you can test for that instead of the DHEA.

-Pp
 
I have used it for 3 days, but I am also battling a cold so not able to report much as the cold makes my perception a bit off as you can imagine.

I have noticed a slight increase in mood elevation though.

I will report back.
 
Primordial Performance said:
It depends on what your interested in diagnosing, or learning more about.

Most guys test DHEA, testosterone and E1 (or E2)

FYI, If you think your under a lot of stress and want to see if you cortisol is high, then you can test for that instead of the DHEA.

-Pp
before and after derma

2dm5lde.jpg
 
RottenWillow said:
Damn! How long after the cycle end was the second sample taken?
second sample was taken 2 weeks into the cycle of derma so I still had another 2 weeks to go and at the end my test would have bin even higher.we are working on after use testing as well. :)
 
needtogetas said:
second sample was taken 2 weeks into the cycle of derma so I still had another 2 weeks to go and at the end my test would have bin even higher.we are working on after use testing as well. :)

yeah definitely get an aftercycle check as well. I'd like to see how long your T takes to return to baseline.

I just did my third day and it seems my energy is better. Not sure it that's from the Dermacrine or not though.
 
RottenWillow said:
yeah definitely get an aftercycle check as well. I'd like to see how long your T takes to return to baseline.

I just did my third day and it seems my energy is better. Not sure it that's from the Dermacrine or not though.
thats cool.....but watch out people will just say your taking out your ass when this stuff really kicks in and you start feeling it.week 1 and you will know what I mean.
 
Like I've said before, saliva testing is completely and utterly useless for testing hormone levels (save cortisol). Why are you people getting your panties in a bunch over this?

Ah... EF... where I come for laughs.
 
JimmyPineapple said:
Like I've said before, saliva testing is completely and utterly useless for testing hormone levels (save cortisol). Why are you people getting your panties in a bunch over this?

Ah... EF... where I come for laughs.

REAAALLLLY. I'm assuming you're referring to a reasonably recent article along the lines of this one:http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1579286 that stipulates that the accuracy of male testosterone monitoring (saliva) is VERY SIMILAR to plasma monitoring.

I wouldn't call that "completely and utterly useless".

Although it's probable that a blood test is more accurate, it's also significantly more annoying. The purpose of this test was (amongst other things) to see if Test went up with Dermacrine. It doubled.

We are here to help each other not make fun of people! (except for C&C :D)

edit: I was a bit harsh in my initial response
 
trez said:
REAAALLLLY. I'm assuming you're referring to a reasonably recent article along the lines of this one:http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1579286 that stipulates that the accuracy of male testosterone monitoring (saliva) is VERY SIMILAR to plasma monitoring.

I wouldn't call that "completely and utterly useless".

Although it's probable that a blood test is more accurate, it's also significantly more annoying. The purpose of this test was (amongst other things) to see if Test went up with Dermacrine. It doubled.

We are here to help each other not make fun of people! (except for C&C :D)

edit: I was a bit harsh in my initial response


interesting read
 
trez said:
REAAALLLLY. I'm assuming you're referring to a reasonably recent article along the lines of this one:http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1579286 that stipulates that the accuracy of male testosterone monitoring (saliva) is VERY SIMILAR to plasma monitoring.

I wouldn't call that "completely and utterly useless".

Although it's probable that a blood test is more accurate, it's also significantly more annoying. The purpose of this test was (amongst other things) to see if Test went up with Dermacrine. It doubled.

We are here to help each other not make fun of people! (except for C&C :D)

edit: I was a bit harsh in my initial response
nice read
 
I don't know what there is to question. If you take DHEA your test will go up. That's pretty basic. People have been using DHEA for years with similar results.
 
worldclass said:
I don't know what there is to question. If you take DHEA your test will go up. That's pretty basic. People have been using DHEA for years with similar results.
and with a trans dermal its even better.plus all the other ingredients in derma= :) people
 
solidspine said:
Anthony Roberts,

Do you take gear?

Do you go to the gym?



The guy has posted pics... Lets see some of yours bro.




-)#
 
Some of my pics?

Why?

I have posted pics here dozens of times,


Got a problem with my question?


I have seen pics of Anthony Roberts and he does not look like a guy that goes to the gym, or takes gear.

Not calling him a fake or a fraud, did not ask for his credentials, I asked a serious, a no drama question,


It’s a simple yes or no.

He does or does not,


I have heard he does not, I have heard he does not go to the gym, the pics I have seen confirm it, In stead of making an acquisition, I asked a question,

It’s for him to answer not you or anyone else.

I recently read a non flattering bio of Anthony Roberts and I could have just as easily posted that here. But thought I would ask him an honest question and hope for a serious response.



So if you read my question it is directed to Anthony Roberts, and if that is not your name, give him an opportunity to answer it.
 
solidspine said:
Some of my pics?

Why?

I have posted pics here dozens of times,

Got a problem with my question?

I have seen pics of Anthony Roberts and he does not look like a guy that goes to the gym, or takes gear.

Not calling him a fake or a fraud, did not ask for his credentials, I asked a serious, a no drama question,

It’s a simple yes or no.

He does or does not,

I have heard he does not, I have heard he does not go to the gym, the pics I have seen confirm it, In stead of making an acquisition, I asked a question,

It’s for him to answer not you or anyone else.

I recently read a non flattering bio of Anthony Roberts and I could have just as easily posted that here. But thought I would ask him an honest question and hope for a serious response.

So if you read my question it is directed to Anthony Roberts, and if that is not your name, give him an opportunity to answer it.



So testy! Dayum!


Bro, all I'm getting at is that nobody should call anybody out about their physique unless they have Pics of their own... AR has pics of himself in his gallery, most people who call him out or have bad shit to say about the guy do not... I see that same pattern here day in and day out...

Also, just because your goals are to get ad big as possible, don't expect others to share the same goals... Some of us are more concerned with performance/lifestyle than just sheer mass... Maybe AR might not meet your standard of a pro Bodybuilder, but the guy is a rugby player. As far as Rugby players go, he might be just fine or maybe even ripped...

Personally, I'm all about the fight game... Honestly, I have had some personal difficulties that have keep me from the dojo in months... But I still maintain a physique that can easily be considered above average...

And even if I didn't, I'm a fighter... The very best fighter in all of the world, the best fighter to have ever put on a pair of fingerless gloves, looks like this:

fedor_20winner.3.jpg


I don't have much to live up to physique wise...





&%^%
 
Big Rick Rock said:
And even if I didn't, I'm a fighter... The very best fighter in all of the world, the best fighter to have ever put on a pair of fingerless gloves, looks like this:

fedor_20winner.3.jpg


I don't have much to live up to physique wise...

Laff, dont compare yourself to Fedor just because you fight, if you even enter competitions ( sparring doesent count ).

Fedor would kick your ass silly in 30 seconds flat. Dont insult him by comparing yourself to him, physique wise or anyway else.
 
KD1 said:
Laff, dont compare yourself to Fedor just because you fight, if you even enter competitions ( sparring doesent count ).

Fedor would kick your ass silly in 30 seconds flat. Dont insult him by comparing yourself to him, physique wise or anyway else.

Did you even read the thread before posting on it?

He was saying Fedor was the best fighter in the world, and his point was you can be the best in MMA without having a great physique. He did not compare his abilities to Fedor's. You can find plenty of ppl on this board with much better physiques, but Fedor is still the best fighter, that was his point. Read posts before you post on them, you are like a child wandering into the middle of a movie, you have no frame of reference here.
 
D_Mac said:
Did you even read the thread before posting on it?

He was saying Fedor was the best fighter in the world, and his point was you can be the best in MMA without having a great physique. He did not compare his abilities to Fedor's. You can find plenty of ppl on this board with much better physiques, but Fedor is still the best fighter, that was his point. Read posts before you post on them, you are like a child wandering into the middle of a movie, you have no frame of reference here.
na bro the just blurt out random piles of shit most of the time.its funny how many jail house lawyers we have around here.
 
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