Interesting, from
http://www.ultimatefatburner.com/relacore-review.html:
Cortisol is the body's main stress hormone, and is required for many vital purposes -- proper glucose metabolism, blood pressure, immune function and inflammatory response are a few. In times of stress, either mental or physical, the body can produce an excessive amount of cortisol. At these high levels, cortisol is a nasty little number indeed. It can negatively affect cognitive performance, suppress thyroid function, foster blood sugar imbalances and the subsequent deposition of body fat, decrease bone density, as well as other things. Athletes don't like cortisol, as it is catabolic -- i.e., muscle-wasting, rather than anabolic -- i.e., muscle building.
Bottom line?
Excess cortisol levels may indeed be *somewhat* responsible for excess fat deposition and weight gain, no doubt about it (you'll see why I say "somewhat" a little later on).
OK, now back to Relacore. The main ingredient, as it pertains to cortisol control, is Magnolia bark. Here's what SupplementWatch.com has to say about Magnolia bark...
"... a small dose of honokiol, or a magnolia bark extract standardized for honokiol content, can help to "de-stress" you without making you sleepy, while a larger dose might have the effect of knocking you out.
When compared to pharmaceutical agents such as Valium (diazepam), honokiol appears to be as effective in its anti-anxiety activity, yet not nearly as powerful in its sedative ability."
This "anti-anxiety" effect appears to be backed up by numerous animal studies (that, of course, doesn't mean it will work in an identical fashion in humans, but it does look promising). However, while the honokiol element of Magnolia bark may be an effective anxiolytic agent (J Pharm Pharmacol 2000;52:1425-9) there is no scientific data that validates its ability to lower cortisol levels.