there have been some abstracts posted recently here and on AF that say estrogen up-regulates the PR receptor. This would explain why I was able to use anadrol/tren and not get gyno, test by itself and not have many problems, but tren or anadrol + test does give me problems.
i remember that Bill Roberts take on anadrol is that it up-regulates the ER, so that is why it should not be taken with aromatizing steroids...might actually be the reverse though (estro upregulating PR)..whichever it is I do believe their is a cumulative or even synergistic gyno effect when combining estrogenic and progestenic compounds.