crystals which are "in" the skin..an amount which will vary by skin type and hydration level can be eliminated (also whether skin is wet or dy when applied) by wetting hands/fingertips and rubbing the area(s).. this can be done immeadiately after application of 15min to 2hrs after application.. if done immeadiately it may slightly increase systemic uptake.. (be more stimulatory.. whish some people may prefer..) in most people crystals slowly penetrate/dissolve over time.. though in dry climates or if you have dry skin.. wetting the hands and lightly rubbing sites will take care of it..