Transdermal Application

[solidspine]

You're going to waste 90% of your gear. If you delivered 10% you'd be doing well. You have to have a delivery solution that is made for steroids.

That is all there is to say, no big deal.


It is like taking 1000mg of test a week and only benefiting from 100mg a week.

 

[needtogetaas]

The ester is cleaved from the hormone before it even reaches the blood stream. Using a hormone with an ester (in a topical) is only going to hurt absorption. Even with a base hormone, there is still a 12-18 hr timed release effect depending on your topical carrier.

Besides, the max flux seen an hour after application mimics a more natural release of hormones. Ie, a burst of testosterone in the morning similar to the bodies natural rhythm. Plus, transdermaly applied base hormones clear the system within days, making for a very quick rebound.

The only pitfall with transdermal testosterone base is excessive aromatization & 5-alpha reduction as it passes the skin. This is why I would opt for nandrolone base in a topical.

Eitherway, topical test base is cheap, powerful, and painless… not to mention very fast acting.

-Pp

sounds good to me.

 

[blut wump]

So, if we assume raw hormone dissolved at 20mg/ml with a 35% absorption, that's 7mg per ml applied. Four 1ml squirts night and morning would make for a very acceptable cycle, comparable with shooting 50-60mg of suspension per day. One squirt per day is a decent HRT run.

There's the usual possibility of skin damage, as with any topical, but if you're in a situation where needles aren't available or acceptable then it seems a reasonable avenue to consider.

 

[Ulter]

I know how esters are cleaved. But thanks.

Like I said, twice, blood levels of test will swing wildly up and down using test base in a delivery solution transdermally. In Androgel the test levels swing up and down by over 50% in just few hours. That's for 5mg. Now if you do that with 100mg your side effects from spiking will be much worse than if the test in a ester in a depot.

So, d_mac, I'm glad to hear you found a way to get over your fear of needles. But the fact is that cycling transdermally is a bad idea.

 

[Primordial Performance]

I know how esters are cleaved. But thanks.

Like I said, twice, blood levels of test will swing wildly up and down using test base in a delivery solution transdermally. In Androgel the test levels swing up and down by over 50% in just few hours. That's for 5mg. Now if you do that with 100mg your side effects from spiking will be much worse than if the test in a ester in a depot.

So, d_mac, I'm glad to hear you found a way to get over your fear of needles. But the fact is that cycling transdermally is a bad idea.

Ulter,

A 50% swing in test levels can happen after a work out, or even jacking off. If your concerned about a 50% swing in hormone levels, you should be concerned about the 1-2 gram wk/ testosterone cycles that are happening on this board, causing upwards of a 5000% "swing" in testosterone levels. Im wondering now, what horrible side effects will be seen with this spike in testosterone?

Transdermally applied steroids can work very well. There really is no argument here.

FYI, after several days of topical steroid administration to the same spot, the dermis does become saturated with hormone, creating a depot for steady hormone release.

Blut wup,

What sort of skin damage are you referring to?

DMSO does have the capability to change skin integrity and structure, so I could consider this to be skin damage. However our topical formula DOES NOT contain DMSO and does not cause any kind of irritation even in the most sensitive individuals.

-Pp

 

[blut wump]

All interesting stuff.

It's good to hear that you have a skin-friendly formula. Ulter's formulation has never given me any problems over occasional months of use either.

I had read specifically about DMSO causing the damage you mention. I was about to write that I'd be loathe to consider very long-term application of any solvents onto the skin but then I realised that I dose myself with soap and deodorant daily. The soap is an emulsifier but the water washing it off is definitely a solvent. Alcohols do still concern me, though.

Thanks to you and Ulter for the info you've each provided here.

 

[needtogetaas]

wonder if any one here has ever had a really bad irritation from a topical.

 

[Ulter]

Ulter,

A 50% swing in test levels can happen after a work out, or even jacking off. If your concerned about a 50% swing in hormone levels, you should be concerned about the 1-2 gram wk/ testosterone cycles that are happening on this board, causing upwards of a 5000% "swing" in testosterone levels. Im wondering now, what horrible side effects will be seen with this spike in testosterone?

-Pp

Actually those are closer to 200%. But you are comparing apple and oranges. You can't compare 3-5mg per day test swings with the swings caused by adding a 1000mg of test per week. The whole reason you use an ester in a depot is to get even blood levels while using 1000mg/wk. The side effects don't come from the test. They come from the estrogens, prolactin, progestins, etc. Taking 1000mg/wk of test is no problem for those using an AI like AIFM. There are hundreds of men using over a gram a week with AIFM and have NO side effects. The success rate of AIFM for those using over a gram is nearly 100%. Now if they were spiking their test levels up and down 200% who knows how bad the sides would be. Mainly because they wouldn't be dosing the AI to match up with the test spiking.

Put aside your love of transdermal for a minute. If you use suspension and inject it daily your side effects are much greater then if you use an esterfied test in a depot. If you don't think so, try it. Esters in a depot are a better choice.

I said the swings from Androgel are 50%. I'm sorry that was off the top of my head. It's closer 300%.

 

[rykertest]

http://www.jarpharma.com/ultrais.html

 

[Ulter]

Hey!!! That's Carl's stuff!!! I don't see that posted much.