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Testosterone 17-chloral hemiacetal

lanky

Well-known member
Add testosterone dissolved in benzene anhydride into chloral solution and incubate for a few minutes by shaking until being clear solution. Further incubation results in formation of solid precipitates. Filter, wash with benzene( please do this under a hood, benzene is very dangerous kids), and dry at room temperature until yielding hemiacetal. M.p.194-196 C. Hemiacetal can be formed as crystal in ethylacetate( run some qualitative data if you have a standard) (m.p. 200-201 C).

Remarkable increase in androgenic activity through conversion of 17-hydroxy group of testosterone to methoxy. Testosterone 17-Chloral Hemiacetal possesses 4-5 times stronger androgenic potency than testosterone propionate in rat. However, the acetate exhibits only half a titer of testosterone propionate. God knows what this will do to your liver. Be safe
 
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