Clen actually lowers BP, but still it does effect the heart as do stimulants like NKTS. I would be a liar if I told you I have never taken adderllin with clen. I do not take clen often, but when I do it makes me tired so on occasion I have taken adderllin and it has helped me. Now both are two very strong thermogenics and together holy crap. My usual intention is to take adderllin only on my off days, but like I said it can make me too tired to even work out.