AS usage does predispose oneself and increase the risks of cardiovascular disease, maybe not directly, but more so indirectly. For example, Triglyceride levels, cholesterol levels are adversely affected as well as the HDL/LDL ratio. This ultimately can lead to atherosclerotic heart disease, and we all know can lead to increased risk of myocardial infarctions, cardiac ischemia and angina and increased risk of stroke. AS usage can stimulate erythropoeisis and increase the viscosity of blood and the potential for vascular problems such as the development of a thrombus or even emboli. Hence, the increased risk of the development of an MI, stroke and angina.
As far as the chances of cardiomyopathy and cardiomegaly, I'm exactly unsure of the pathology behind AS use and these diseases. I would venture to say that blood pressure increases, increases in blood viscosity, the development of athersclerosis and arteriosclerosis over time can lead to left ventricular heart failure from the increased workload the left ventricle must pump against. Over time this can lead to enlargement and inefficiency of the left ventricule and if continued to progress can end up causing both right and left sided CHF.
Like stated, no one is the same. Genetic predisposition to cardiovascular diseases will definitely play a role.
Modifiable risk factors must also be looked at. Of course smoking, drinking, drug usage, AS usage, hypertension, overall health, diet, activity level should be assessed. Other risk factors that are not modifiable, or only treated, include pathological diseases such as diabetes, hypercholesterolemia, preexisted cardiovascular problems, ect..
I've used myself, so I'm not bashing AS, however, there are associated problems with AS and increase ones risk for pathological processes to take place. So, I'd say use your own personal judgement, stay healthy, modify risk factors and use within moderation.