I've always used protection combos that include milk thistle, ALA, and picroliv, most of which have all been proven to cleanse, detoxify, and even regenerate the liver. And yes they help immensely because 17AA orals are very toxic, as are many other oral prescription drugs, and shouldn't be taken lightly. It's also good to drink TONS of water when using any oral with protectants, it will help a great deal