Personal opinion and experience is 400mgs is not needed bro..
I Was using 70mg tren ace (0.1ml daily) and even with this I experience mild side affects.
Now using 140mg (0.2ml daily) and the gains are great. I can tolerate the side effects quite well but I also take all my supplements to help with sleep and anxiety levels..
@BodyMonster34 is built different bro !! He can run 500mgs no worries.. it's not wise for others
But short answer to your question is yes you can go straight into Anavar.. Its a little concerning though when users have extremely low knowledge of peds.