Another DNP related death

[bwood]

i have seen no evidence that humans
are more susceptable to anaphalactic
shock from dnp than from any other drug...

it is dangerous as the LD50 is not far removed
from the effective dose and it is purported to
have an acumulative effect in the body that can
bite the uninformed who insist on pushing the envelope...

it is not mutagenic according to the ames test, but
i have read articles citing increased cell senescene...

what worries me, aside from the free radical shitstorm(which may be mitigated), is the possibility of permanent mitochondrial damage/loss...

are you as ever as "ATP fit" as you were pre-dnp?

does cellular metabolism return to baseline or
is it permanently, albeit tiny, altered for the worse???

 

[Antti]

Hah, ok antti:

http://www.pslgroup.com/dg/214fe2.htm

"Acetaminophen poisoning is one of the most common types of poisoning and is placing an enormous financial burden on hospitals, particularly as these patients are traditionally managed in intensive care units.

Acetaminophen is an effective and safe painkiller. However, if taken in excess it can be fatal. Taking an acetaminophen overdose overwhelms the liver's ability to process the drug. The excess acetaminophen is then processed into toxic chemicals, which can kill liver cells. If enough cells are killed the patient can die from liver failure. "

Oh wow! It's legal aswell! I bet your parents have a years supply of the shit in their medicine cabinet too. Ok well this is the last time I'm argueing anything about DNP, i'm a humble person, you guys can believe what you want, just be smart.

-J

Ok. My point is that we know what is excess use in Acetaminophen, but do you claim to know what is excessive in the use of DNP? Do you have any scientific proof of that? That's my point.

 

[HULKSTER]

i have seen no evidence that humans
are more susceptable to anaphalactic
shock from dnp than from any other drug...

it is dangerous as the LD50 is not far removed
from the effective dose and it is purported to
have an acumulative effect in the body that can
bite the uninformed who insist on pushing the envelope...

it is not mutagenic according to the ames test, but
i have read articles citing increased cell senescene...

what worries me, aside from the free radical shitstorm(which may be mitigated), is the possibility of permanent mitochondrial damage/loss...

are you as ever as "ATP fit" as you were pre-dnp?

does cellular metabolism return to baseline or
is it permanently, albeit tiny, altered for the worse???

You should try to post on the Anabolic Board more often. Your knowledge is quite profound.

 

[halfaclue]

Ok. My point is that we know what is excess use in Acetaminophen, but do you claim to know what is excessive in the use of DNP? Do you have any scientific proof of that? That's my point.

Well I have never heard or read of anyone dying from 250mgs a day so lets say that is a safe doasge. From here on out I decree DNP is safe at 250MGS a day and this is not to be exceeded without the risk of severe cell mutation or death! Now people can use it safely and if anyone goes over that amount they are abusing it and are responsible for the consequences. I'll stick with my 500Mgs but I am a renegade!!!!!

 

[bigAragorn]

i have seen no evidence that humans
are more susceptable to anaphalactic
shock from dnp than from any other drug...

it is dangerous as the LD50 is not far removed
from the effective dose and it is purported to
have an acumulative effect in the body that can
bite the uninformed who insist on pushing the envelope...

it is not mutagenic according to the ames test, but
i have read articles citing increased cell senescene...

what worries me, aside from the free radical shitstorm(which may be mitigated), is the possibility of permanent mitochondrial damage/loss...

are you as ever as "ATP fit" as you were pre-dnp?

does cellular metabolism return to baseline or
is it permanently, albeit tiny, altered for the worse???

tell us what YOU think

 

[HULKSTER]

Bottom line is, people need to stop focusing on the name of the drug, and focus on the potency and quantity of the drug ingested by a user. There are people who have used coke for decades, and have not died yet, because the quantity wasn't enough to kill them. However, there are people who have died from using Tylenol, because they overdosed on it. Thus, it's not so much a matter of the drug itself, but the quantity of that drug that is ingested. To say DNP in itself is deadly is not accurate, to say that you can die from overdosing on DNP IS VERY ACCURATE! Just like you can die from overdosing on Tylenol, coke, inhaling glue, acid, etc.

 

[bigAragorn]

id say a drug is deadly when its critical dose and effective dose are so close together in scale.

 

[I2ancid]

Bottom line is, people need to stop focusing on the name of the drug, and focus on the potency and quantity of the drug ingested by a user. There are people who have used coke for decades, and have not died yet, because the quantity wasn't enough to kill them. However, there are people who have died from using Tylenol, because they overdosed on it. Thus, it's not so much a matter of the drug itself, but the quantity of that drug that is ingested. To say DNP in itself is deadly is not accurate, to say that you can die from overdosing on DNP IS VERY ACCURATE! Just like you can die from overdosing on Tylenol, coke, inhaling glue, acid, etc.

Exactly hulkster!

 

[bwood]

tell us what YOU think

that is the problem...

uninformed deductions are excessively subject to
bias...

three possibilities exist both long and short term...

no long term change:likely? based on the body's tendancy to
maintain homeostasis, possible...purely guesswork...

perm damage/loss:likely? based on cell senescene
theory, possible, but were mitochondria affected as well? they are basically an alien organism incorporated into our cells as a symbiote, what does dnp actually do to them, is cell senescene related to some other unknown factor???

positive change: likely? anabolic rebound effect, is this a result
of mitrochondrial rebound or other metabolic/endocrine processes??? short term only??? how do we know???

dnp is dangerous, so is vancomyacin(sp?), that does not
mean it is unusable...

for the morbidly obese, is it more dangerous than gastric
bypass??? i dont THINK so, if administered by doc knowing
what he is doing...

for the bodybuilder??? this is dependant on individual philosophies as to whether it is proper...dont delude yourself, nothing is safe, steroids are not safe per se, you take a chance everytime you inject of introducing a foreign organism into your body that could kill or sicken you...

 

[bigAragorn]

so in other words the more you look into it (as with anything) the less ( as in you are asking more questions than providing answers ) we know about it.

Agreed.

So it comes down to how bad do you wanna lose the weight and in what period of time.