If you absoulutely have to be on statins, make sure you're supplimenting the crap out of yourself with CoQ10. Eating two whole grapefruits a day is the same as the average statin dose, same active ingredient........my pharmacist admitted that to me accidently. The bad thing statins do is strip the body of CoQ10 which is an important enzyme in the body's mitochondrial energy production. That's where the hand cramps and muscle weakness play in. Not a big deal.......but than you can get issues with your heart and brain. Statins can give you cardiac muscle problems..........not good. They've also been shown to potentially accelerate parkinsons.