My HRT doc seems to think that HGH "mini cycles" will lessen the risk/extent of shutdown (I don't personally know).
For me, I sort of enjoy the 2 days off because it lets any residual edema and/or joint pain lessen by the end of day two (but that may all be in my head too).
For those of you inquiring about winny with tren and masteron. Ive done winny, tren....winny,masteron...and winny,tren,masteron. They all work freaking awesome. I use winny at 100ed. Bam