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What REALLY Grows Muscle?

Nelson Montana

Chairman of Board
Chairman Member
The process of muscle building can be as complex as the most intricate scientific formulation. It requires a multitude of events and the results are never precise. Our bodies are always in a state of flux and there’s no telling if a specific stimulus is going to have a specific result. It’s a lot of guesswork. The key is to be a good guesser. And the best way to do that is to learn as much as you can, and use whatever is available to tip the odds in your favor.

Still, it all comes down to one very simple equation. Muscles grow when they receive amino acids. That’s really pretty much it. So why not just eat a lot of protein? Well, there are two problems with that. One: The muscle will not absord aminos without a need to do so. That’s where training comes in. And the human body is crafty. Once it gets used to a stress it adapts quickly and very little protein is needed for repair. (That’s where having a big vocabulary of training techniques helps – to keep the muscle “confused.”)

The second reason more protein won’t do much is that the aminos are available for just a short time. They do nothing when they’re in the stomach and large intestines – only in the small intestines will they get to the bloodstream and it has to be at a time when there’s a demand for them. They is a LOT of hit and miss. Just a fraction of the protein you eat actually turns into muscle. This leads some so called experts to suggest that you don’t need to eat a lot of protein. Sure… if all the protein you ate was used exactly where it was needed! But that’s never the case. The only way to assure adequate protein is to eat it all day long. That’s what serious bodybuilders do. And it makes a difference.

Okay, that’s simple. So what can be done to increase nitrogen retention beyond eating more protein? The most obvious is the old protein shake. It’s a good way to get concentrated protein in a quick and easily digestible form. We all use them. But protein sakes, for the most part are just another form of food. And more often than not, the type of protein used is inferior to what you’d get in food such as meat, eggs and even milk. (Though milk is high in carbs too).

Protein pills are another way of getting extra aminos. They can be taken at any time, which is a great advantage, but each pill is barely a gram of protein so it’s hardly worth it. Using BCAA’s – the aminos that work directly on muscle growth makes more sense. And until recently, they were the best option.

What else? Oh yeah…something that will increase nitrogen retention a thousand times over. STEROIDS! That’s basically what they do. Steroids are androgenic – giving male characteristics leading to greater strength and recovery so you can train harder therefore increasing the need for more aminos in order to build muscle tissue. Plus, steroids are ANABOLIC which essentially means it re-circulates protein to do what protein does – build, repair and grow. But steroids essentially force the body to do it NON STOP – not just as a hit or miss process. And the results of that are undeniable. It’s what turns mortal men into gods.

But here’s something else. What if there were a way to make protein MORE available? In this way it would not only increase the effectiveness of steroids, you can actually use LESS steroids and get BETTER results. As a matter of fact, even if you didn’t use any steroids at all you could get muscle growth far beyond what a natural athlete , even on a super high protein diet. Well, there is a way – simply INJECT the amino acids directly into the bloddstream. In this way there’s no digestion, no breakdown, not “hit or miss” as to when the aminos can be used. They’d be available all the time. (Well, at least for 12 hours or so until they’re filtered by the liver).

* Incidentally this is one advantage of oral steroids. The 17 alph alkyating process prevents the liver from filtering out protein so you get a few more passes at it. It’s great for muscle growth but it’s a strain on the liver. This may be why instead of using 50 mgs a day as a “kickstart” (Which really doesn’t do muscle since steroids become active within a day or two) it may be better to simply at 5 or 10 mgs a day throughout the cycle to enhance nitrogen retention).

So why aren’t injectable aminos more popular? Actually, they should be. The results are incredible. But they’re not readily marketed and they’re also VERY expensive and injections would be required 2-3 times a day. That’s going to put a damper of its appeal. There’s also a purity issue. Still, it is a tremendous advantage. But today, it isn’t necessary. You can use GEAR. GEAR is a combination of ingredients that work in the same manner as injectable aminos. It requires no digestion and is released immediately into the bloodstream. There’s also an additional advantage of the amino molecules being “fractioned” which allows for a broader disbursement . And GEAR also enhances the potency of other aminos in your system by increasing thir effectiveness and absorption rate. That’s a HUGE advantage in the science of nitrogen retention.

So there you have it. In the end, it’s pretty simple. Protein builds muscle. And you have a few options to work it to your advantage. We all want more muscle and less fat and it takes a lot of time, effort and money to make it happen. Why not give yourself every advantage? . Word is catching on. It isn’t an exaggeration to say that GEAR is probably the biggest innovation in protein supplementation the bodybuilding world has ever had. If you’re not using it, you’re not growing as much as you can. It’s as simple as that.
 
Another gr8 and informative NM post! Thanks bro.
 
Great post Nelson, my man!! I want to contribute some info to this GEM. :)

Exercise increases muscle protein synthesis and plasma levels of Follistatin, Interleukin-5, IGF-1, MGF, HGH, Testosterone, and androgen receptor sensitivity. Anabolic steroids increase follistatin expression.

EXERCISE itself seems to be the ultimate KEY to regulating plasma levels of growth factors(and their expression) in the body, which lends credence to the notion that more frequent bouts of exercise will induce greater hypertrophy(and hyperplasia) in a the enhanced athlete. OVETRAINING? No, just UNDER-eating and inadequate resting. ;)

You must VARY the type of STIMULUS; heavy weight, light weight, higher rep and lower rep. Remember, every time that you EXERCISE you cause a CASCADE of accute biochemical and hormonal responses that increase hypertrophy. ONLY exercise can induce these changes, and it seems logical that if executed properly, with sufficient feeding and resting, the more you can exercise, the more you can increase muscle protein synthesis, Follistatin levels and expression, IGF-1 levels and expression, interleukin-5 levels and expression, androgen-receptor sensitivity and testosterone-uptake--which equates to signficantly greater hypertrophy.

Biologically speaking, training pretty much CONSTANTLY, throughout the day, in multiple divided increments(bouts of exercise), would produce the maximum hypertrophic response. Therefore, these accute biochemical and hormonal responses that occur after EXERCISE are actually directly proportionate to:

1.) The amount of work performed
2.) The intensity of the work performed
3.) The duration of the work performed

From an evolutionary standpoint, this makes perfect sense. The body must adapt, and it will upregulate, downregulate, increase or decrease functions accordingly, in order to do so. Imagine how muscular a body would become after adapting to such an exercise protocol.

THIS STUDY shows IGF-1 levels increase with INTENSE exercise:

J Clin Endocrinol Metab. 1996 Oct;81(10):3492-7.
Acute effect of brief low- and high-intensity exercise on circulating insulin-like growth factor (IGF) I, II, and IGF-binding protein-3 and its proteolysis in young healthy men.
Schwarz AJ, Brasel JA, Hintz RL, Mohan S, Cooper DM.
SourceDepartment of Pediatrics, UCLA Medical Center, Torrance 90509, USA.

Abstract
We measured circulating levels of the GH insulin-like growth factor (IGF) system in response to brief exercise of different intensities. Ten males (mean age 28 +/- 5 yr) were studied on three separate occasions: once under resting conditions (control) and once each performing 10 min of low- or high-intensity exercise. Blood samples were assayed by RIA for GH, IGF-I and -II, IGF-binding protein-3 (IGFBP-3), and IGFBP-3 proteolytic activity. After 10 min of low-intensity exercise, IGF-I and IGFBP-3 had increased over preexercise baseline by 7.7 +/- 2.7% (P < 0.05) and 12.5 +/- 3.3% (P < 0.004), respectively. After 10 min of high-intensity exercise, all measured components of the IGF system were increased: IGF-I by 13.3 +/- 3.2% (P < 0.002), IGF-II by 15.7 +/- 3.1 (P < 0.01), and IGFBP-3 by 23 +/- 6% (P < 0.001). IGFBP-3 proteolytic activity also was increased (44 +/- 14% above baseline, P < 0.05). GH reached its peak 10 min after the cessation of high-intensity exercise, unlike the earlier peaks of IGF-I and II. In summary: 1) brief exercise leads to small but significant increases in circulating IGF-I, IGF-II, IGFBP-3, and IGFBP-3 proteolysis; and 2) these responses may be influenced by exercise intensity. The IGF responses seem to be unrelated to GH. Acute exercise-induced proteolysis of IGFBP-3 may contribute to anabolic effects of physical activity by increasing the bioavailability of IGF-I.
 
Another very interesting study on how EXERCISE itself is the KEY regulating GROWTH, even on STEROIDS:

[Ergo-Log]

Training makes methandrostenolone – the active ingredient in the classic steroid Dianabol – more active. According to an animal study soon to be published in Archives of Toxicology, intensive training boosts the muscle-growth effect of methandrostenolone… in muscles you haven't even trained.



The researchers, working at the German Sport University Cologne, are doing fundamental research on anabolic steroids and their side effects. For this experiment they gave half of a group of male rats the equivalent of 50 mg methandrostenolone per day, and the other half nothing. The researchers 'dissolved' the steroid with DMSO in groundnut oil, and injected the rats with the oil.


The researchers then trained half of the animals in each group and did not train the other half. Training consisted of getting the rats to run at high speed in a mill for 15 minutes a day. The speed was meant to imitate the exertion of a strength training session. The experiment lasted 21 days.


In the figures below C stands for the rats that did not train and were not given methandrostenolone; T for the rats that trained but were not given methandrostenolone; M for the rats that were given methandrostenolone but did not train and MT for the rats that trained and were given methandrostenolone.


The rats did not train their levator ani muscle. The growth of this muscle is a classic indicator of the anabolic effect of anabolic steroid hormones. Nevertheless the muscle grew more in the rats that had trained and taken methandrostenolone than in the rats that were only given the steroid and didn't train. The combination resulted in an increased production of the androgen receptor [AR] in some muscles and in the prostate.

dboltraining.gif


Nevertheless, the prostate was the same size in the MT and the M group rats after 21 days.


The researchers are not sure why this was the case, but it seems that training activates methandrostenolone [structural formula show above] in such a way that the steroid induces muscles that you are not training to grow as well. At the same time training ensures that the undesirable androgenic side effects of methandrostenolone don't increase. Strange. Very strange
 
Love Gear!! This is why Nate called me up on another note but I ordered a case...24 bottles. Trying to get it all out of food would cost ya exponetially more $$
 
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