from what i understand anavar is not all that toxic as long as cycles are not longer than 8-10 weeks i think people usually cycle it for 10-12 weeks.take some milkthistle and stay away from the liquor and youll be ok ,anavr is one of the mildest anabolics available excellent for a first cycle .i am looking to get some myself i would do a search on the anabolics board about anavar ther are people there who use up to 50mg a day i think the longer cycle would give better results just my 2 cent