Test Kills brain cells?

[golferstud84]

When i was taking a poo tonight, i was flipping through the recent Mens Health magazine and read an article on testosterone

T-Level Dangers:
" Elevated levels of testosterone cause brain cells to self-destruct, according to Yale University scientists. Luckily, it only happens if you have 10 times the normal levels, which can be reached only by taking steroids. Researchers found that estrogen protects cell health"


any truth to this?

 

[jokerswild]

oh fuck i'll be brain dead after my next cycle

 

[ole farte']

i'm doing my first cycle of 500mg test-e and i don't feel any stoopider than normal.

 

[BigBlu]

When i was taking a poo tonight, i was flipping through the recent Mens Health magazine and read an article on testosterone

T-Level Dangers:
" Elevated levels of testosterone cause brain cells to self-destruct, according to Yale University scientists. Luckily, it only happens if you have 10 times the normal levels, which can be reached only by taking steroids. Researchers found that estrogen protects cell health"


any truth to this?

Nonsense. I'd be working in MacDonalds if that was the case!

Check who funded the study and you'll see what the intention behind that Men's Health study is.

 

[Svengali]

Hmmmm... That explains the retarded threads by some of the old timers on this board

 

[solidspine]

“Yale University scientists” have never said anything that ever made sense,

I seriously wonder how many Yale University scientists workout, go to the gym or even walk around the block.


Hmmm, wouldn’t be amazing if there own personal biases and prejudices and jealously enter in to their “study”

Leave that paper where you are, it may be of some use, if you run out of toilet paper.



Dumb Fucks

 

[paradox]

well that certainly would explain alot

 

[Svengali]

Hmmm, wouldn’t be amazing if there own personal biases and prejudices and jealously enter in to their “study”

Word.
But, I wouldnt really call Yalies dumb fucks.

 

[redsamurai]

testosterone, GH.....all responsible for regeneration of dendrites. This has been known for decades. General tissue regeneration happens with all AAS........so it's bullshit. And no I'm no doctor.....but I've read studies going back for years about this. If T kills brain cells........why do old men who get an infusion of testosterone all of a sudden regain their mental faculties? I realize this is not taking into account uber doses that some of us take........but it being in mens health is suspect. There's a crusade to demonize roids and GH in this country. Just look at the countries where roids are legal......any stupider than we are? India, China, Iran, Greece......yeah.......it's likely bullshit.......unless they were talkking about 2-3 grams a week, in which case I have no comment.

 

[strength_honor]

I be take Test, and I be not stoopid. I not maybe take enuff.

Getch

 

[solidspine]

But, I wouldnt really call Yalies dumb fucks.

But I would

Stanford class of 72, thank you.

 

[cuthroat]

I actually read the full article I believe this was drawn from about a year ago on

CNN.com, There argument was something along the line of estrogen protecting the

brain cells and your body not being able to do that while on test. However when you

are on test some is going to be converted to estrogen like it or not correct? More

protection for your brain cells from test. Rofl. I am sure the study is a bunch of BS,

society has stereotyped steroids to the point no matter how many times you try and

convince someone there not all bad as they are cracked up to be they won't even

bother to listen. I had Psych professor who on the 2nd day of class gave a don't do

steroids because "theyll shrink your balls and slowly kill you - you won't live to 30" bs

speech. WTF seriously its so messed up you can kill yourself with fucking aspirin and

tons of other over the counter drugs if abused will kill you, yet the freaking

government believes the taboo bullshit they are fed and list it as a controlled

substance...A bunch of crap and I doubt they will ever do anything to correct it: at

least not in my lifetime. This country is headed downhill anyway I doubt it will be

around for another 200 years.

 

[redsamurai]

I This country is headed downhill anyway I doubt it will be

around for another 200 years.

200 years?? that's a generous estimate my friend. If I were a bettin man..........it would be alot less than 200

 

[cuthroat]

200 years?? that's a generous estimate my friend. If I were a bettin man..........it would be alot less than 200

True. I guess I didn't want to sound like a complete pessimist.

 

[solidspine]

I had Psych professor who on the 2nd day of class gave a don't do

steroids because "theyll shrink your balls and slowly kill you - you won't live to 30" bs

You won’t live to be 30? Go ask the governor of California


I’m 57 and still on.


I think the technical term quoted was


Dumb Fucks


I’m simply tired of all the non scientific discussion about the hazards of gear, show me the study, show me the bodies, and show me any real hazards.

Nothing, it is all antidotal, all of it, nothing scientific or proven detrimental, when there have been literally hundreds of thousands of great athletics taking gear totally unsupervised, for decades.
My governor looks just fine and he was on at least 30 years.

 

[Svengali]

But I would

StanfUrd class of 72, thank you.

Impressive. I heard they finally instituted the "F" a couple years ago. There goes their inflated grades
CAL'97

 

[Svengali]

My governor looks just fine and he was on at least 30 years.

UMM... I saw him in a speedo in cabo last year.. it wasnt fine

 

[redguru]

Ugg blunk brog.

 

[Harleymarleybone]

i'm doing my first cycle of 500mg test-e and i don't feel any stoopider than normal.

Hehe. That's funi. (800mg Test)

 

[solidspine]

I was accepted to Yale, have you ever seen there Campus, it is in New Haven an industrial slum, scum in the water, in the air, nothing to do, slums from Boston to NYC

Now Palo Alto, is the Garden of Eden compared to New Haven.

And seriously what is the single most important necessity of a great university,


That’s right Chicks, and California has Chicks, New Haven, well enough said.

 

[Cutt29]

I was accepted to Yale, have you ever seen there Campus, it is in New Haven an industrial slum, scum in the water, in the air, nothing to do, slums from Boston to NYC

Now Palo Alto, is the Garden of Eden compared to New Haven.

And seriously what is the single most important necessity of a great university,


That’s right Chicks, and California has Chicks, New Haven, well enough said.

New Haven is a fucking DUMP, solid didnt know you were so edumakated bro

 

[Svengali]

I was accepted to Yale, have you ever seen there Campus, it is in New Haven an industrial slum, scum in the water, in the air, nothing to do, slums from Boston to NYC

Now Palo Alto, is the Garden of Eden compared to New Haven.

And seriously what is the single most important necessity of a great university,


That’s right Chicks, and California has Chicks, New Haven, well enough said.

Bro. Cali has chicks.. But, there are none at Stanfurd, or CAL, or Yale...etc. Palo Alto is gorgeous. But, their women arent. Things may have changed from the time you were there. But, Let me tell you, in order to find decent poon, you must seek it off campus.. Now, SoCal schools are different. USC, UCLA, SDSU< USD OH MY GOD!

Wow Sorry for Hijacking the thread

 

[wags8]

Hey Stew. Been deleted lately? Just kidding. No need to answer, they're everywhere.LOL.

 

[Harleymarleybone]

I was accepted to Yale, have you ever seen there Campus, it is in New Haven an industrial slum, scum in the water, in the air, nothing to do, slums from Boston to NYC

Now Palo Alto, is the Garden of Eden compared to New Haven.

And seriously what is the single most important necessity of a great university,


That’s right Chicks, and California has Chicks, New Haven, well enough said.

Hehe. Newport has a few chicks, too. (UC Irvine alum here). Met lots of chicks when I lived on Balboa Peninsula.

 

[Svengali]

I was in cali the other day.. at that club sutra.... OMG.. Whats this have to do with being dumb on testosterone...

 

[halfcenturian]

Only some of the younger, naive, cheesedick, members would even ASK about such a retarded statement...... :Gymgurl

 

[golferstud84]

good post halfcenturian... way to contribute

 

[samoth]

LOL @ a college prestige thread in the juicer forum!

Hey, at least no one on this thread goes to the festering TTT in decline Penn State...

... oh, wait... lol.

 

[macrophage69alpha]

And seriously what is the single most important necessity of a great university,


That’s right Chicks, and California has Chicks, New Haven, well enough said.

 

[Svengali]

LOL @ a college prestige thread in the juicer forum!

I am just insecure with my physical development. So, I must brag about something

 

[samoth]

I am just insecure with my physical development. So, I must brag about something

I hear MIT has the hottest chicks in the country.

 

[SgtSlaughter]

I hear MIT has the hottest chicks in the country.

depends on what your type is...

 

[samoth]

Elevated Testosterone Kills Brain Cells

Main Category: Endocrinology News
Article Date: 28 Sep 2006 - 16:00 PST


A Yale School of Medicine study shows for the first time that a high level of testosterone, such as that caused by the use of steroids to increase muscle mass or for replacement therapy, can lead to a catastrophic loss of brain cells.

Taking large doses of androgens, or steroids, is known to cause hyperexcitability, a highly aggressive nature, and suicidal tendencies. These behavioral changes could be evidence of alterations in neuronal function caused by the steroids, said the senior author, Barbara Ehrlich, professor of pharmacology and physiology.

"Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad, just take a deep breath and realize that it might not be his fault," said Ehrlich.

Testosterone is the main male hormone and it plays fundamental roles in development, differentiation, and cellular growth. In neurons, testosterone acts as a neurosteroid and can induce changes at the cellular level, which in turn lead to changes in behavior, mood and memory. Both neuroprotective and neurodegenerative effects of androgens have been reported.

The researchers showed that high levels of testosterone triggered programmed cell death in nerve cells in culture. Cell death, or apoptosis, is critical in many life processes, including development and disease. It is characterized by membrane instability, activation of caspases, which are the executioner proteins in apoptosis, change in membrane potential, and DNA fragmentation.

"In the present study we have demonstrated for the first time that the treatment of neuroblastoma cells with elevated concentrations of testosterone for relatively short periods, six to 12 hours, induces a decrease in cell viability by activation of a cell death program," Ehrlich said. "Low concentrations of testosterone had no effects on cell viability, whereas at high concentrations the cell viability decreased with incremental increases in hormone concentration."

The testosterone-induced apoptosis described in this study occurs through overactivation of intracellular Ca2+ signaling pathways. Overstimulation of the apoptotic program in neurons has been associated with several neurological illnesses, such as Alzheimer disease and Huntington disease.

###

Co-authors include Manuel Estrada, now continuing his work at the University of Chile in Santiago, and Anurag Varshney, now working at Ranbaxy, a drug discovery company in New Delhi, India.

Journal of Biological Chemistry 281: 25492-25501 (September 2006)

Contact: Jacqueline Weaver


Sounds somewhat prejudice... we'd really have to see the full article for details.

 

[redsamurai]

I still call bullshit.........it's just like growing up when I was told how stupid weed makes you. Yet the most profound spiritual and intellectual experiences of my life are a result of marijuana use. Now, I'm not a pot head that smokes every day......in fact, I don't smoke anymore because I want to keep my lungs clean......but I take my weed other ways.

 

[SgtSlaughter]

I still call bullshit.........it's just like growing up when I was told how stupid weed makes you. Yet the most profound spiritual and intellectual experiences of my life are a result of marijuana use. Now, I'm not a pot head that smokes every day......in fact, I don't smoke anymore because I want to keep my lungs clean......but I take my weed other ways.

If you're saying some people of a lesser intelligence that smoke pot, naturally will be of lesser intelligence during and after smoking green I agree.

And that goes for most things. Study's are skewed.

I bet someone could find the antithesis to that study with 5 minutes of goggling.

Do you inject your mary jane now?

 

[macrophage69alpha]

"Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad, just take a deep breath and realize that it might not be his fault," said Ehrlich.

perhaps now we'll be eligible for ADA protection

 

[redsamurai]

hell yeah...I'm free basin that shit now!! and don't even get me started on the "green suppositories"!!!

If you're saying some people of a lesser intelligence that smoke pot, naturally will be of lesser intelligence during and after smoking green I agree.

And that goes for most things. Study's are skewed.

I bet someone could find the antithesis to that study with 5 minutes of goggling.

Do you inject your mary jane now?

 

[ironclaw]

I'm already brain dead, so I"m not worried about a little test, I think that article refers to very large dosages of test, if its the same article i read

 

[marvelous54]

When i was taking a poo tonight, i was flipping through the recent Mens Health magazine and read an article on testosterone

T-Level Dangers:
" Elevated levels of testosterone cause brain cells to self-destruct, according to Yale University scientists. Luckily, it only happens if you have 10 times the normal levels, which can be reached only by taking steroids. Researchers found that estrogen protects cell health"


any truth to this?

Yeah that's why no one lives past the age of 16. Our test levels get to high and we just die. Were all just elecrical pulses now.

How can any fucking responsible person write a fucking article like that? They act like taking test just all of a sudden makes you super natural and your body just can't take it.