and you base this on what? your personal view or actual hard science? provide actual evidence to back up your statement please. I'll go first in regards to nolva and can keep going and going if needed.
For newer guys,
tamoxifen = nolvadex:
Nolvadex-Tamoxifen Citrate - iSteroids.com
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Exp Clin Endocrinol. 1988 Dec;92(2):211-6.
Hormonal changes in tamoxifen treated men with idiopathic oligozoospermia.
Hampl R,
Heresová J,
Lachman M,
Sulcová J,
Stárka L.
Research Institute of Endocrinology, Prague/Czechoslovakia.
Three months of
tamoxifen treatment of 43 men with idiopathic oligozoospermia, out of which 20 completed the study, resulted in a significant enhancement of sperm motility, but the improvement of sperm parameters was in no relation to the FSH response to short time tamoxifen treatment.
There was a significant increase of testosterone, estradiol, LH, FSH,
SHBG, 17 alpha-hydroxy-progesterone and also of 11 beta-hydroxyandrostenedione, an androgen of exclusively adrenal origin, during the treatment and (with the exception of the latter), on the first week after discontinuation of the therapy.
Significantly elevated testosterone and SHBG concentrations were retained still 9 weeks after finishing of the therapy.
The results confirm that tamoxifen treatment provides conditions more favourable for conception and demonstrate that also adrenal steroidogenesis is positively influenced by this antiestrogen.
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Int J Androl. 1987 Dec;10(6):747-51.
Stimulation of calcitonin secretory capacity by increased serum levels of testosterone in men treated with tamoxifen.
Schopman W,
Slager E,
Hackeng WH,
Mulder H.
Department of Internal Medicine, Eudokia Hospital, Bergsingel, Rotterdam, The Netherlands.
Abstract
Previous studies have suggested that sex steroids, including both oestrogen and
testosterone, influence calcitonin secretion. However, a negative effect of gonadotrophins on calcitonin has not been excluded.
Twelve men with infertility and low-normal serum levels of testosterone were studied before and during tamoxifen therapy.
Increases in the serum levels of LH, FSH, testosterone and calcitonin were observed after treatment. Our findings suggest that
testosterone has a direct influence on calcitonin secretion.
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Fertil Steril. 1978 Mar;29(3):320-7.
Hormonal effects of an antiestrogen, tamoxifen, in normal and oligospermic men.
Vermeulen A,
Comhaire F.
Abstract
The
administration of tamoxifen,
20 mg/day for 10 days, to normal males produced a moderate
increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of
Clomiphene citrate (Clomid). However, whereas Clomid produced a decrease in the LH response to LH-releasing hormone (LHRH), no such effect was seen after the administration of tamoxifen. In fact,
prolonged treatment (6 weeks) with tamoxifen significantly increased the LH response to LHRL. Treatment of patients with "idiopathic" oligospermia for 6 to 9 months resulted in a significant increase in gonadotropin,
testosterone, and estradiol levels. A significant increase in sperm density was observed only in subjects with oligospermia below 20 X 10(6)/ml and normal basal FSH levels. When basal FSH levels were increased or oligospermia was moderate (greater than 20 X 10(6)/ml); no effect on sperm density was seen. As sperm density increased, FSH levels decreased, suggesting an inhibin effect. Sperm motility was not improved by tamoxifen treatment. In five boys with delayed puberty, tamoxifen treatment appeared to activate the pituitary-gonadal axis and pubertal development.
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