the sides are the same, im just saying sust usually doesnt develope as severe, example water retention, honestly ive never ever ever had gyno, and never taked nolva during a cycle either, so i couldnt tell you bout that but water rentetion, sust is better than E, that is prob becuase like i said you dont have to USE as much, you could get awesome results from 500mg sust, and it would take maybe 750mg E, sust is a combo of 4 test, that work synergeticly together 1+1+1+1=5 basically thats the example i mean, you dont have to use as much to get the same result... so obviously theres less a chance of side effects... they both willl make you bigger, my friends first cycle though was 10weeks of sust and he gained 40lbs, on sust alone, so that why i would suggest it cus it worked for him, but theyll both work, if you eat!!!!! OH AND JC is right, PCT is a must with this stuff, do your homework before you start pokin..