Drugs of any kind do not make you tougher but probably more aggressive. Size intimidates individuals who do not have the heart and the balls. I'm 160lb and have stood up to guys over 220lb on drugs. IMO, its how you carry yourself and the size of your heart (balls) based on my own experience. People who put on size and go about picking fight with others are the most insecure individuals that could be intimidated easily. 
