Something I Admit I Don't KNow

[Nelson Montana]

Then again, I've never seen it addressed.

Since orals stop the liver from breaking down the chemicals in the drug, and consequently, causing stress and prohibiting the liver to do its job and filter out impurities, it stands to reason it would also allow other androgens to pass through unfiltered, ergo, if you use an injectable with an oral, it would not break down as quickly. So in a sense, orals make any cycle more productive beyond the actual addition of more drugs.

Any scientists care to elaborate?

Also, Bioperine increases absorption of many compounds. Can this be why such low doses of adex are needed when using POST CYCLE -- which contains bioperine?

Just another factor on the synergy of compounds. There's a lot that has yet to be explored.

 

[chazk]

you know what nelson a old time bodybuilder told me drank a few beers a day ,
the liver would be impaired by breaking down the beer that the steroids would last longer in the system
I thought he was nuts , but now I am not to sure about it. kinda makes some sense that if you can keep the liver doing other things maybe the steroids will last longer

 

[needtoworkout]

Interesting theory, but I'm not sure I want my liver functioning too poorly. With all of the other pills my doctors prescribe, I need at least 50% liver functioning, LOL!

 

[Mavafanculo]

I think the bioperine would have general benefit for all ingested oral compounds, with the proviso that the studies were only done with a few vitamins and at 5mg per dose.

but I'm thinking the 17aa alteration affects only the molecule to which its attached - without carryover benefit. iow, I believe the enzyme activity that would otherwise occur is blocked rather than the enzyme being inhibited

 

[OMEGA]

Bioperine and Narigen are proven uptake compounds

 

[needtogetaas]

I think the bioperine would have general benefit for all ingested oral compounds, with the proviso that the studies were only done with a few vitamins and at 5mg per dose.

but I'm thinking the 17aa alteration affects only the molecule to which its attached - without carryover benefit. iow, I believe the enzyme activity that would otherwise occur is blocked rather than the enzyme being inhibited

The usage of 17alpha-alkylated steroids is strongly linked to elevated total cholesterol, and decreased HDL. So we can at least speculate that the alkylation is allow more then just the aas to pass threw the liver. Fats? if fats what else?

We already know its not the steroid its self because not all steroids have this effect on cholesterol/hdl/ldl.

 

[bw1]

Then again, I've never seen it addressed.

Since orals stop the liver from breaking down the chemicals in the drug, and consequently, causing stress and prohibiting the liver to do its job and filter out impurities, it stands to reason it would also allow other androgens to pass through unfiltered, ergo, if you use an injectable with an oral, it would not break down as quickly. So in a sense, orals make any cycle more productive beyond the actual addition of more drugs.

Any scientists care to elaborate?

Also, Bioperine increases absorption of many compounds. Can this be why such low doses of adex are needed when using POST CYCLE -- which contains bioperine?

Just another factor on the synergy of compounds. There's a lot that has yet to be explored.

I think Synergy of compounds plays more into building good cycles then people realize

 

[OMEGA]

I think Synergy of compounds plays more into building good cycles then people realize

makes ALL the difference in the world

 

[bw1]

makes ALL the difference in the world

I agree...we should put together more info on this and sticky it

 

[Mavafanculo]

The usage of 17alpha-alkylated steroids is strongly linked to elevated total cholesterol, and decreased HDL. So we can at least speculate that the alkylation is allow more then just the aas to pass threw the liver. Fats? if fats what else?

We already know its not the steroid its self because not all steroids have this effect on cholesterol/hdl/ldl.

I dont think its the 17aa that causes the cholesterol problem tho-

- Miotolin is a 17aa oral, and actually RAISES hdl and lowers ldl even at hi does

- if I take 30 mg of 17aa var, my hdl disappears. if I take 60 or 70 mg Dbol, theres only a moderate drop in hdl. if the culprit was 17aa, it would be the reverse

- non 17aa's also cause lipid issues