Taking Clomid at night is a good way to avoid nasty sides if you do experience them. It certainly helped me. I experience headaches, extreme irritability, and sometimes blurred vision but when I started taking it before bed-all gone. Incidently, although I agree Clomid is essential at the end of a cycle, it is hard on the liver. If you look in a medical/pharmacology text elevated liver enzymes is listed as a precaution/side effect during therapy and liver disease is listed as a contraindication. I would interpret that to mean it is not easy on the liver. I'm sure there are other things which are worse though.