Hey everyone I have been doing some research on this cytomel after being prescribed it for an augmentation for antidepressants as well as a low thyroid. I am currently taking 37.5 mcg (25 in the morning then 12.5 around 2-3pm). This is about my 3rd week taken it and I have noticed that if I take it on an empty stomach and don't eat for 2 hours after I feel no affect from it, but if I take it and then eat say 30 mins after I feel it's affects. Has anyone had experience with this. Also is there a certain dosage where the weight loss benefits are at it's peak while the negative impact on the thyroid is at it's lowest. I am not planning on cycling it do to the fact I am prescribed it and most likely will be taking it for a loooooong time or life. I am not overweight at all, probally sitting around 9% 10% BF, but I was previously 6-8%. My diet is clean low carb. I train for boxing 6 days a week, but still notice a lil fat gain (or could it be water?). Anyone with experience with T3 or just hypothyroidism in general I would appreciate some insight.