Remember to turn of the "restore feature" in windows then remove the spyware/adware. After you have cleaned up the system turn the restore feature back on. (this cheats a poorman's way of cleans any registry entries ...kinda)I have found if spybot S&D can't remote it while running windows in safe mode. You might want to get profession help.
Get rid of Norton. Such a resource hog and AVG does everything better. Running 2 antivirus programs is not advisable. Turn off spysweeper from running all the time. Just csan with it every once in a while. Use that along with spybot and adaware and you will be fine. Be sure in spybot to immunize too.
Also download spywareblaster. It is free and it will sit there and pick off spyware before they are installed.