Proviron does not hinder hpta recovery

[Juice Authority]

Have you seen this:

http://www.anabolicfitness.net/library/recovery.htm

??????

Yes I have but we're discussing alternatives to clomid therapy, which in part includes Nelson's post cycle formula.

 

[muscleup]

I'm running Proviron@50 mgs per day along with .25 mgs per day of arimidex...I have done this all the way through clomid therapy...I have actually increased my strength post cycle...My questin being, Am I just wasting my arimidex ?...Could the proviron do the trick by itself... ?

 

[Juice Authority]

I'm running Proviron@50 mgs per day along with .25 mgs per day of arimidex...I have done this all the way through clomid therapy...I have actually increased my strength post cycle...My questin being, Am I just wasting my arimidex ?...Could the proviron do the trick by itself... ?

Well, it's hard to say for sure since there is no real concrete evidence that shows Proviron keeps estrogen from binding to the HPTA but Nolva would be a much better option since it accomplishes the same thing without messing up your lipid profile. Nolva actually improves your lipid profile.

 

[muscleup]

Well, it's hard to say for sure since there is no real concrete evidence that shows Proviron keeps estrogen from binding to the HPTA but Nolva would be a much better option since it accomplishes the same thing without messing up your lipid profile. Nolva actually improves your lipid profile.

So you are saying run the Nolva instead of arimidex ?..I was actaully running the Arimidex along with some clen. I'm trying to get rid of or at least reduce some a2 fat deposits that I have acquired from Bulking...

 

[muscleup]

imo, yes. Nolva should work to reduce some of those estrogen related fat deposits. In fact, Nolva is the only anti-e that has clinically been shown the reverse gyno after it's been formed.

I took a blood test after my PCT therapy where I was using 1mg of Arimidex Eod and my HDL was 9 and my LDL was 230.

Arimidex, it is an anti-e. It stops aromatation. Problem is, it will mess up your cholesterol levels.

Arimidex = To Prevent Estrogen Creation

Nolvadex = To Stop Estrogen from Binding

Nolvadex can and will act as a psuedo-estrogen. Arimidex will keep your aromatose activity down to a minimum. Nolva can take the place for estrogenic activities for cholesterol. Which is good! Another noteworthy fact about Nolvadex is that it acts more potently as an estrogen in the liver.

Here's a study showing nolva lowers femara levels in the system when combined.

Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer.

Dowsett M, Pfister C, Johnston SR, Miles DW, Houston SJ, Verbeek JA, Gundacker H, Sioufi A, Smith IE.

Department of Biochemistry, Royal Marsden Hospital, London, United Kingdom.

This study examined whether the addition of tamoxifen to the treatment regimen of patients with advanced breast cancer being treated with the aromatase inhibitor letrozole led to any pharmacokinetic or pharmacodynamic interaction. Twelve of 17 patients completed the core period of the trial in which 2.5 mg/day letrozole was administered alone for 6 weeks and in combination with 20 mg/day tamoxifen for the subsequent 6 weeks. Patients responding to treatment continued on the combination until progression of disease or any other reason for discontinuation. Plasma levels of letrozole were measured at the end of the 6-week periods of treatment with letrozole alone and the combination and once more between 4 and 8 months on combination therapy. No further measurements were done thereafter. Hormone levels were measured at 2-week intervals throughout the core period. Marked suppression of estradiol, estrone, and estrone sulfate occurred with letrozole treatment, and this was not significantly affected by the addition of tamoxifen. However, plasma levels of letrozole were reduced by a mean 37.6% during combination therapy (P<0.0001), and this reduction persisted after 4-8 months of combination therapy. Letrozole is the first drug to be described in which this pharmacokinetic interaction occurs with tamoxifen. The mechanism is likely to be a consequence of an induction of letrozole-metabolizing enzymes by tamoxifen but was not further addressed in this study. It is possible that the antitumor efficacy of letrozole may be affected. Thus, sequential therapy may be preferable with these two drugs. It is not known whether tamoxifen interacts with other members of this class of drugs or with other drugs in combination.

Well thats good cause the Arimidex(Astra Zeneca) is WAY more expensive than the Nolvadex...Karma bro...Thanks

 

[Juice Authority]

So you are saying run the Nolva instead of arimidex ?..I was actaully running the Arimidex along with some clen. I'm trying to get rid of or at least reduce some a2 fat deposits that I have acquired from Bulking...

imo, yes. Nolva should work to reduce some of those estrogen related fat deposits. In fact, Nolva is the only anti-e that has clinically been shown the reverse gyno after it's been formed.

I took a blood test after my PCT therapy where I was using 1mg of Arimidex Eod and my HDL was 9 and my LDL was 230.

Arimidex, it is an anti-e. It stops aromatation. Problem is, it will mess up your cholesterol levels.

Arimidex = To Prevent Estrogen Creation

Nolvadex = To Stop Estrogen from Binding

Nolvadex can and will act as a psuedo-estrogen. Arimidex will keep your aromatose activity down to a minimum. Nolva can take the place for estrogenic activities for cholesterol. Which is good! Another noteworthy fact about Nolvadex is that it acts more potently as an estrogen in the liver.

Here's a study showing nolva lowers femara levels in the system when combined.

Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer.

Dowsett M, Pfister C, Johnston SR, Miles DW, Houston SJ, Verbeek JA, Gundacker H, Sioufi A, Smith IE.

Department of Biochemistry, Royal Marsden Hospital, London, United Kingdom.

This study examined whether the addition of tamoxifen to the treatment regimen of patients with advanced breast cancer being treated with the aromatase inhibitor letrozole led to any pharmacokinetic or pharmacodynamic interaction. Twelve of 17 patients completed the core period of the trial in which 2.5 mg/day letrozole was administered alone for 6 weeks and in combination with 20 mg/day tamoxifen for the subsequent 6 weeks. Patients responding to treatment continued on the combination until progression of disease or any other reason for discontinuation. Plasma levels of letrozole were measured at the end of the 6-week periods of treatment with letrozole alone and the combination and once more between 4 and 8 months on combination therapy. No further measurements were done thereafter. Hormone levels were measured at 2-week intervals throughout the core period. Marked suppression of estradiol, estrone, and estrone sulfate occurred with letrozole treatment, and this was not significantly affected by the addition of tamoxifen. However, plasma levels of letrozole were reduced by a mean 37.6% during combination therapy (P<0.0001), and this reduction persisted after 4-8 months of combination therapy. Letrozole is the first drug to be described in which this pharmacokinetic interaction occurs with tamoxifen. The mechanism is likely to be a consequence of an induction of letrozole-metabolizing enzymes by tamoxifen but was not further addressed in this study. It is possible that the antitumor efficacy of letrozole may be affected. Thus, sequential therapy may be preferable with these two drugs. It is not known whether tamoxifen interacts with other members of this class of drugs or with other drugs in combination.

 

[nadr7891]

My only apprehension about Proviron is, due to its androgenic nature, that it seemingly is pretty rough on the hair... this is further confirmed by some of its users...

Can anyone shed anymore light Proviron with respect to hair loss?

i just came off a short cycle that ended with 30mg Winny ED, 100mg Test Prop EOD and 25-50mg Proviron ED (depending on whether or not fucking was eminent). according to what i've read over the past few months this combination should have been very hard on my hair... but it wasn't. i had no shedding and no visible recession of the hairline, and i have MPB. i would tend to agree with Nelson on the dubious role of DHT in hairloss.

it should be noted that i used every precaution: minoxidil ED, polysorbate 80 ED and finasteride 1mg around EOD (depending on whether or not fucking was eminent).

 

[Nelson Montana]

I'd also add that e related fat deposits, although not necessarily a total myth, are a bit of an exageration. e will increase water retention, which looks fat, but you can lose water. The actual fat thought to be gained from e is usually just good old fashioned fat. On the other hand, proviron does make you hard, but not so much from the actual reduction of e but the lessened water, the incresed free T and the fact that DHT seems to increase muscle hardness. (For reasons I'm not fully sure of).

 

[Deleted member 33117]

I'd also add that e related fat deposits, although not necessarily a total myth, are a bit of an exageration. e will increase water retention, which looks fat, but you can lose water. The actual fat thought to be gained from e is usually just good old fashioned fat. On the other hand, proviron does make you hard, but not so much from the actual reduction of e but the lessened water, the incresed free T and the fact that DHT seems to increase muscle hardness. (For reasons I'm not fully sure of).

Good point. I've noticed the hardening effect when on proviron. Anyone have an answer on why DHT derivatives (such as proviron, primo and winstrol) see to increae muscle hardness? There has to be a reason, anyone have a solid theory on this?

 

[Juice Authority]

Good point. I've noticed the hardening effect when on proviron. Anyone have an answer on why DHT derivatives (such as proviron, primo and winstrol) see to increae muscle hardness? There has to be a reason, anyone have a solid theory on this?

I don't know how solid this theory is but here it goes..

Proviron decreases the total water build-up of the body giving the appearance of muscle hardness. This is most likely due to its reduction in circulating estrogen or perhaps due to the downregulating of the estrogen receptor in muscle tissue.