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Prohormones: The Real Deal

MIKERAZ said:
O you mean 18 as anabolic not more anabolic. i thought you meant 18 percent more . That makes sense , so 1-test is 7 percent as also and methyl-19nor-5-ad is also 7 times AS potent.


1-Test is 2-7 times more potent than testosterone.
methyl-19-nor-5AD is 7 times more potent than methyltest.
methandriol has only 18% of the potentcy of testosterone

Ok now it makes sense, but methyl-19nor-5-ad also would have intrinsic estrogen ability

Just like it must be weak because it is a diol? Mikeraz, you cannot make blind assumptions about the activities of steroids like this. You have no understanding of steroid chemistry, and are basing these judgements soley on what you read on bodybuilding websites.
 
But its in the 5 position ,5 positions are androgenic and estrogenic .


And i still stand by my comment that no Diol EVER assayed out better then its Beta-Hydroxy'd Brotha.

These judgements are based on my knowledge aquired through websites, big catt hh,Animal basically.
 
mike raz=smacked assed animal wannabe with theories based on comic book science....so mikey what do you think about cosmic rays?
 
MIKERAZ said:



Got a problem with that statement. First off 5-ad isnt a potent steroid. Second Methyl-5ad is Methandriol and Methandriol has little to no anabolic properties. Third off it aromatises very very easily and not very anabolic and isnt 7 times more potent.

And to answer the original question besides for `1-t,5ad,4ad no other Pro-Hormones have been methylatyed, i gess the pharm companies learned there lesson after methylating the first to Pro-Hormones , and that lesson is not to waste time on presecuers that arent potent.



Please shut up. You know nothing about the pharmacology and chemistry of steroids. So please, just shut up
 
MIKERAZ said:



You actually never seen me at all so thats a dumb comment.

And notpuff of all the dumb posts from you that takes the cake!.Test is not in anyway a Pro-hormone in anyway!!!! The molecules are diffrent, There actiosn are diffrent .




No mike, notpuff is totally correct. Testosterone is a prohormone to DHT and estradiol.

Fact is, you do not even know the definition of prohormone. Good Lord you don't know anything.
 
w_llewellyn said:


Hence the 18% :rolleyes:

[/B]

Aromatase inhibitors do not help because it is intrinsically estrogenic.



All of the diols are also active steroids, regardless of whethor or not they convert to anything else. Furthermore 1-test is not a diol, but one of the most potent natural steroids ever isolated. It is not a prohormone to anything.

You are clueless, and stuck on a term rarely used outside of supplement advertising. These all classify as steroids. [/B]


JUst to nitpick, we really don't know whether the diols are active intrinisically or not. But thats just semantics anyway. anadrol probably isn't intrinisically active either. Shit, anadrol might very well be a prohormone! Yes, thats no shit. Try that one on for size MikeRaz
 
w_llewellyn said:


1-Test is 2-7 times more potent than testosterone.
methyl-19-nor-5AD is 7 times more potent than methyltest.
methandriol has only 18% of the potentcy of testosterone



Just like it must be weak because it is a diol? Mikeraz, you cannot make blind assumptions about the activities of steroids like this. You have no understanding of steroid chemistry, and are basing these judgements soley on what you read on bodybuilding websites. [/B]


MikeRaz, by nothing more than pure luck (after all if you guess about shit 1000 times you are right once or twice), actually is probably right about the methyl nor-5-diol being estrogenic because the non-methylated nor-5-diol has shown very strong binding to the ER (quite a bit more even than 5-diol)
 
MIKERAZ said:
But its in the 5 position ,5 positions are androgenic and estrogenic .


And i still stand by my comment that no Diol EVER assayed out better then its Beta-Hydroxy'd Brotha.

These judgements are based on my knowledge aquired through websites, big catt hh,Animal basically.

Big Cat and animal are NOT reliable sources of information buddy.

So if what you say about all delta 5 steroids is true then i guess that pregnenolone, diosgenin, and cholesterol are all androgenic and estrogenic too?

Furthermore, methyl-4-AD assayed out MORE anabolic than its beta-hydroxy analog (methyltestosterone). So there goes that theory

Got any more brilliant comments? Be sure to check with your aforementioned sources (aka dumb and dumber) before getting back to us
 
Wow slow down here i never said you dont know any information and are not knowledgable , i do respect your knowledge and innovations allot . But theres also room for the knowledge of animal and others who i get most of my info from.

How in the world is anadrol a prohormone and not have anabolic activity and not have activity ? Anadrol isnt a diol and is beta-hydroxy'd.

And you said the diol's might not have anabolic activity then how in the world could methyl-4ad have activity? if the base isnt anabolic, neither is it methylated cousin.
 
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